• 06-02-2014 05:23 AM
    matlondon
    Dkk1 Stimulate Hair Follicles For Hair Growth When They Appear Dead
    http://hairdresserslivingston.blogsp...loss-2014.html

    sounds good, but i'd like to see some actual stuff we could use.
  • 06-02-2014 06:00 AM
    thechamp
    I wonder if you can block dkk1 topically ?
  • 06-03-2014 04:31 AM
    thechamp
    Why is there no interest in this
  • 06-03-2014 06:15 AM
    Thinning87
    Quote:

    Originally Posted by thechamp View Post
    Why is there no interest in this

    Because this is old news. We ready discussed it. It falls under the research lead by the university of pennysylvenia.
  • 06-03-2014 06:49 AM
    bananana
    this is very, very interesting. Another piece of the puzzle revealed.
  • 06-03-2014 03:04 PM
    rdawg
    Very interesting stuff.

    Clearly multiple ways that scientists are solving the problem, it just seems that clearly safety has to be tested as we are messing with our own bodies proteins and cells.

    I'm really just interested in a bridge treatment right now, Fin/Min aren't strong enough for my agressive hairloss, they only slow it down, I need another anti-androgen like CB or even BIM to hurry up!!
  • 06-03-2014 03:28 PM
    youngin
    You can forget this. This is old news: http://www.ncbi.nlm.nih.gov/pubmed/17657240

    DHT -> DKK-1

    I highly doubt it would be any better than a topical finasteride.
  • 06-03-2014 04:01 PM
    beetee
    Quote:

    Originally Posted by thechamp View Post
    Why is there no interest in this

    I follow a lot of the press releases fairly closely, particularly those from Penn, and I missed this, or at least the potential significance of this. When it comes down to it, all of the stuff we talk about on here is for the most part very theoretical in its effects (for example, there's nothing that says as good as CB or Histogen-style treatments seem like they could be means that they won't encounter some unsolvable problem somewhere down the road), and as long as we're talking about something that's theoretical but seemingly plausibly effective, this is as good a candidate as I've seen.
  • 06-03-2014 05:23 PM
    Swooping
    Doesn't work. They are exploring drugs (and doing clinical trials) which antagonize DKK1 to repress the WNT pathway, DKN-01 and BHQ 880. If it would work i bet they would see some side effect in hair increase.
  • 06-03-2014 05:39 PM
    beetee
    Quote:

    Originally Posted by Swooping View Post
    Doesn't work. They are exploring drugs (and doing clinical trials) which antagonize DKK1 to repress the WNT pathway, DKN-01 and BHQ 880. If it would work i bet they would see some side effect in hair increase.

    Swooping, I'm not sure I follow you. From what you say, it sounds like trials and experiments are underway. When you say it "doesn't work," do you mean you have a gut instinct that it won't work or do you mean that they've tried every likely way to do this and none of them have worked?

    Also, if you could post any links or specifics on trials or experiments related to this, it would be greatly appreciated.

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