New breakthrough

GOD PLEASE GEORGE COTSARELIS

http://www.medpagetoday.com/Dermatol...matology/31755

Hmmm......

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Whether blocking the GPR44 receptor would allow the regrowth of hair after balding -- or just prevent balding in the first place -- remains an open question. It also remains to be seen whether inhibiting the receptor would have any effect in humans.

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Originally Posted by gmonasco

Hmmm......

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Sounds like you would have to keep applying this stuff regularly to stop your hair from falling out or to grow and keep hair. Would be ok if they had a tablet option but a topical would mean you would get your hair back but it would be covered in greasy crap all the time.

I wasn't able to read the entire article.. i'm at work and it blocks part of it..

Quick question, is this treatment ( if it's true ) only for existing follicles, or will it work on bald men.

Thanks.

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Originally Posted by sausage

Sounds like you would have to keep applying this stuff regularly to stop your hair from falling out or to grow and keep hair. Would be ok if they had a tablet option but a topical would mean you would get your hair back but it would be covered in greasy crap all the time.

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Sounds like a treatment using knowledge from these discoveries would have to be regular, yes. But it doesn't necessarily mean it'd have to be daily, or twice daily. Far too early to tell. Still, it's a very welcome breakthrough, and I hope it leads to creation of more (and better) treatments before too long.

Seems like the same old story. Nothing too exciting. Replicel excites me more than this.

If it works then great, but needs to be a topical that we don't have to use regularly....or hopefully they can treat this orally.

You know how much rubbish an baldness-article is by the amount of 'may' they use.

You read these kind of articles about 500 times a year. Don't hold your breath for it.

There are so many potential cures around at the moment that pretty much all claim to be available within 5 years......

Will any of them work...We can only hope. What annoys me is that if one of these treatments is significantly successful at getting our hair back and keeping it then it will be bitter sweet for me as I will probably into my 30's and ideally I needed it 10 years ago. I was born 10 years to frigging early!

So whats currently in progress to potentially cure as all in the near future:

Theres this thing reported in this thread.
Theres some fat cell injection.
Theres Replicel.
Theres Histogen.
..........

Sausage,

Being very insecure in my 20's because of bad acne I didn't get around to doing nearly as much as I'd liked. Now 32 and balding rapidly I'd still be enthusiastic about a cure for baldness as I believe someone in their 40's would be too. Still, if it comes around in 5 years I'll probably make a snide comment or two about it coming later than I'd liked.

Interesting article, good read. Hopefully blocking that receptor doesn't affect much else.

Interesting thing here is how Niacin(Perscription Niaspan) increase PGD2 at the skin level causing the sever flush. Although in the prescribing info and post marketing reports DO NOT show hair loss as a side effect.

Thoughts

i wonder why we have not seen a single before/after pic of any of these "breakthrough treatments".. could it be because none of them actually work.. sad :(

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Originally Posted by ravegrover

i wonder why we have not seen a single before/after pic of any of these "breakthrough treatments"

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Because they aren't "treatments"; they're biological discoveries that may or may not lead to effective treatments for hair loss someday.

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http://www1.actelion.com/en/scientis...tipiprant.page

Ongoing phase 3 trial for controlling GPR44 receptor for curing asthma.
i wonder these conductors are also looking at hair growth.if not, costarelis and others should inform them about their discovery, so we wouldn't need a seperate trial for hair growth.

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Originally Posted by ohnolosingit

Interesting thing here is how Niacin(Perscription Niaspan) increase PGD2 at the skin level causing the sever flush. Although in the prescribing info and post marketing reports DO NOT show hair loss as a side effect.

Thoughts

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This is the most interesting point raised out of all the talk about PGD2. If there are already drugs out their that increase and decrease PGD2 levels for various ailments, there must be some indication if these are affecting hair to any significance as a side affect?

Historically ,scientific research in Medicine is also usually very SERENDIPITOUS. There is usually never a 'quick fix' cure, medically speaking.
Yes baldness has always been around but has there ever been so much SERIOUS focus on finding a viable treatment for it before,,especially with the latest technology available. Technology, i might add,that is EVOLVING and growing all the time. Look up the history of Polio and how it had been around forever. Not until the 'community' at large had set out to destroy it, hypothetically it would still be a scourge to this day.
Look ahead to our horizon with positive eyes people.