• 09-05-2012 10:12 AM
    Ball D
    Do I really need all that Fin???
    Being a young guy who has only recently started the balding process, I would assume that my DHT levels have only gone up a small amount to warrant this small amount of thinning.

    Since I wasn't balding before this DHT increase, is it safe to assume that I do not need to lower my DHT levels by as much as 70% as Fin does?

    Would a better outcome not be to lower my DHT levels with Fin to a degree that corresponds to the amount they have increased in the past year or so? Say, if they have increased 15% should I not try a Fin dosage that lower DHT by 15%?

    :o
  • 09-05-2012 10:21 AM
    gutted
    Quote:

    Originally Posted by Ball D View Post
    Being a young guy who has only recently started the balding process, I would assume that my DHT levels have only gone up a small amount to warrant this small amount of thinning.

    Since I wasn't balding before this DHT increase, is it safe to assume that I do not need to lower my DHT levels by as much as 70% as Fin does?

    Would a better outcome not be to lower my DHT levels with Fin to a degree that corresponds to the amount they have increased in the past year or so? Say, if they have increased 15% should I not try a Fin dosage that lower DHT by 15%?

    :o

    spot on. maintain the balance or you will pay for it with your hair. Of course merck do not reccomend this as the trial was designed for one dosage.
  • 09-05-2012 11:10 AM
    Tracy C
    Ball D,

    You really need to pose questions like this to a doctor. I agree that a lower dose for some guys should make sense - but I'm not a doctor.
  • 09-05-2012 11:58 AM
    clandestine
    Lower dosage does not mean lowered DHT reduction. Research.
  • 09-05-2012 12:16 PM
    Ball D
    Quote:

    Originally Posted by clandestine View Post
    Lower dosage does not mean lowered DHT reduction. Research.

    Minimum effective dose of Fin is .2mg, which has been found to be as effective as 1mg or 5mg. That is it suppresses up to 70% DHT.

    So somewhere between .0mg and .2mg there is going to be an amount that suppresses say, 30%. Logical, no?

    But humour me, what research are you referencing?
  • 09-05-2012 12:37 PM
    clandestine
    Quote:

    Originally Posted by Ball D View Post
    Minimum effective dose of Fin is .2mg, which has been found to be as effective as 1mg or 5mg. That is it suppresses up to 70% DHT.

    So somewhere between .0mg and .2mg there is going to be an amount that suppresses say, 30%. Logical, no?

    But humour me, what research are you referencing?

    Tough to say; finasteride does not necessarily act logically, given its fairly flat response curve, even for doses as small as 0.01mg.

    "Scalp skin DHT levels declined significantly by 13.0% with placebo and by 14.9%, 61.6%, 56. 5%, 64.1%, and 69.4% with 0.01, 0.05, 0.2, 1, and 5 mg doses of finasteride, respectively. Serum DHT levels declined significantly (P <.001) by 49.5%, 68.6%, 71.4%, and 72.2% in the 0.05, 0.2, 1, and 5 mg finasteride treatment groups, respectively."

    Also, with such low doses, you would need to consider the dissolution of pills in ethanol perhaps in order to administer with any accuracy.
  • 09-05-2012 12:57 PM
    2020

» IAHRS

hair transplant surgeons

» The Bald Truth

» Recent Threads

How can I promote my own business?
08-31-2022 01:29 PM
Last Post By samibaceri
Today 01:30 AM
Dr Woods doinf European tour?
09-15-2012 03:44 AM
by didi
Last Post By kathysmith
Today 01:29 AM
teeth bleaching near me
11-21-2023 07:05 AM
Last Post By KenyaFuentes
Yesterday 01:34 PM
The Mane Event for Thursday, June 15th, 2023
06-15-2023 02:59 PM
Last Post By gisecit34
Yesterday 02:15 AM