ruxolitinib

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  • 09-22-2016 11:37 AM
    ducu72
    ruxolitinib
  • 09-22-2016 03:17 PM
    BoSox
    Pray this works for AGA not just AA.
  • 09-23-2016 03:54 PM
    allTheGoodNamesAreTaken
    I thought this stuff weakens your immune system...
  • 09-24-2016 05:22 PM
    beetee
    "We expect JAK inhibitors to have widespread utility across many forms of hair loss based on their mechanism of action in both the hair follicle and immune cells," said Dr. Christiano.
  • 09-25-2016 01:02 PM
    BoSox
    Quote:

    Originally Posted by beetee View Post
    "We expect JAK inhibitors to have widespread utility across many forms of hair loss based on their mechanism of action in both the hair follicle and immune cells," said Dr. Christiano.

    So basically, we're cured.
  • 09-27-2016 08:30 AM
    Swooping
    Quote:

    Originally Posted by BoSox View Post
    So basically, we're cured.

    Ain't you cured already by TRX2 though? :D
  • 09-27-2016 09:46 AM
    BoSox
    Quote:

    Originally Posted by Swooping View Post
    Ain't you cured already by TRX2 though? :D

    Ugh, that was below the belt.

    Save us christianoooooooooo
  • 09-27-2016 02:10 PM
    Ruby
    Have any of you priced what ruxolitinib costs? I just googled it and seems to be around $11K for 60 pills. Ouch!

    https://www.drugs.com/price-guide/jakafi
  • 09-28-2016 05:02 PM
    beetee
    Quote:

    Originally Posted by BoSox View Post
    Ugh, that was below the belt.

    Save us christianoooooooooo


    :D
  • 09-28-2016 05:11 PM
    beetee
    The whole pricing thing would probably be a wait and see thing if they started using it for this application. My assumption is that that price factors in that insurance would be paying for it if it was being used for its original application. Since HL would likely be considered cosmetic, I think the great majority of insurance companies would not pay for it. However, I don't know if it would ultimately be cheaper, the same, or more expensive than the price that website lists.

    Take it for granted that every super rich balding SOB will be on board as soon as this comes out, so the company could rely on guaranteed sales from that segment no matter how high they priced it. Or they may decide that there's a lot of married family men that would buy it if it was reasonably priced but not if it's super expensive, so to increase the overall consumer base (and thereby get more profits) they might price it more reasonably.

    One thing to think about though is how high nearly all drug companies have been jacking up their prices the last few years, even for life-and-death drugs; most of us have seen in the news some outrage about that (which hasn't often led to the drugs being dramatically reduced in price), but unfortunately I think a lot of people would look at this as something purely cosmetic, elective, and somewhat frivolous, and I don't think there would be a lot of outrage among the non-balding community (the jerks!) no matter how high it was priced.
  • 09-29-2016 10:02 PM
    BoSox
    Does anybody have a guess on how soon we will know if this works for AGA? It just seems too good to be true.
  • 09-30-2016 04:58 AM
    BoSox
    Nevermind, they are testing it first quarter 2017.

    Godspeed.
  • 10-01-2016 04:37 AM
    wolfbeaver
    Source?
  • 10-02-2016 01:31 PM
    beetee
    Quote:

    Originally Posted by BoSox View Post
    Nevermind, they are testing it first quarter 2017.

    Godspeed.

    Bosox, could you provide a source, please? Not doubting you at all, but that's very good news and it would be great to see where the info came from. Thanks!
  • 10-02-2016 04:45 PM
    BoSox
    Quote:

    Originally Posted by beetee View Post
    Bosox, could you provide a source, please? Not doubting you at all, but that's very good news and it would be great to see where the info came from. Thanks!

    I'm trying to find it, somebody on hairloss2020 site commented they will start first quarter 2017, and had link. I'll look for it.
  • 10-03-2016 02:20 PM
    beetee
    Quote:

    Originally Posted by BoSox View Post
    I'm trying to find it, somebody on hairloss2020 site commented they will start first quarter 2017, and had link. I'll look for it.

    Cool, thanks a lot. Also, did you notice if it said the clinical was for AA or AGA applications?
  • 10-03-2016 02:58 PM
    BoSox
    Quote:

    Originally Posted by beetee View Post
    Cool, thanks a lot. Also, did you notice if it said the clinical was for AA or AGA applications?

    He mentioned AGA, I can't seem to find the source now. So I guess you cant take my word for it. Hopefully they will test it soon.
  • 10-04-2016 06:00 AM
    Skin
    Quote:

    Originally Posted by BoSox View Post
    He mentioned AGA, I can't seem to find the source now. So I guess you cant take my word for it. Hopefully they will test it soon.

    I've seen it too.

    Nasa rs is the poster who linked it.
  • 10-04-2016 06:21 AM
    Skin
    http://www.aclaristx.com/pipeline

    Here it the link to potential trials on mpb. With compliments to nasa rs of end hair loss 2020.
  • 10-05-2016 04:47 PM
    beetee
    Quote:

    Originally Posted by Skin View Post
    http://www.aclaristx.com/pipeline

    Here it the link to potential trials on mpb. With compliments to nasa rs of end hair loss 2020.

    Thanks! Am I missing something or does the link just say that they're in preclinical work in regards to AGA? I'm wondering where the 2017 timeframe came from. That would be good to know.
  • 07-13-2019 10:19 PM
    Guide
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