• 06-01-2013 04:57 PM
    bigentries
    Quote:

    Originally Posted by Arashi View Post
    Agreed that silence is a very bad sign in this business. Companies with success usually like to boast them ASAP and publicize any favorable interim result as soon as they can. However I don't agree that this pushes back HM 20 years. Don't forget that Jahoda already succeeded at bio-engineering a human hair follicle and have it grow on human skin !! They just need to optimize it and run trials. But 20 years is way too pessimistic here for something that they've already succeeded doing !

    Is it really pessimistic? It means kids born today wouldn't need to worry about baldness!
    Let's be realistic, every company that got to phase II took a decade to get there, I don't see how new possibilities would arrive to the market in, let's say, less than 15 years

    The thing with Aderans is that, I can't see how they could hide good results. If someone was growing hair like that Simpson's episode where Homer got his hair back, in the middle of America, during the internet era, everyone would know it was happening, non-disclosure agreement or not. The only reliable insider 3 years ago said the results were very mediocre

    Being overly optimistic, I think CB is still in the game, and after the acne trials end, everyone will be able to get it off-label
  • 06-01-2013 05:02 PM
    Arashi
    Quote:

    Originally Posted by bigentries View Post
    Is it really pessimistic? It means kids born today wouldn't need to worry about baldness!
    Let's be realistic, every company that got to phase II took a decade to get there, I don't see how new possibilities would arrive to the market in, let's say, less than 15 years

    The thing with Aderans is that, I can't see how they could hide good results. If someone was growing hair like that Simpson's episode where Homer got his hair back, in the middle of America, during the internet era, everyone would know it was happening, non-disclosure agreement or not. The only reliable insider 3 years ago said the results were very mediocre

    Being overly optimistic, I think CB is still in the game, and after the acne trials end, everyone will be able to get it off-label

    But both Team Tokyo and Jahoda et al already, independently succeeded (!!) at bio-engineering a human hair follicle, growing human hair. They already did it ! It's not science fiction, it was already done ! So getting that to market, it should be possible within 10 years.
  • 06-01-2013 05:07 PM
    bigentries
    Quote:

    Originally Posted by Arashi View Post
    But both Team Tokyo and Jahoda et al already succeeded (!!) at bio-engineering a human hair follicle, growing human hair. They already did it ! It's not science fiction, it was already done ! So getting that to market, it should be possible within 10 years.

    Again, you are being overly optimistic. With this kind of news I would have guessed people would be starting to get more realistic

    Remember Dolly? The human genome? they haven't really translated into new treatments. We know a lot more thanks to those achievements, but people were also expecting the first bio-engineered human to arrive in a decade at most
  • 06-01-2013 05:14 PM
    clarence
    Quote:

    Originally Posted by bigentries View Post
    The thing with Aderans is that, I can't see how they could hide good results. If someone was growing hair like that Simpson's episode where Homer got his hair back, in the middle of America, during the internet era, everyone would know it was happening, non-disclosure agreement or not. The only reliable insider 3 years ago said the results were very mediocre

    Let's be scientifically precise here. Homer has telogen effluvium - not MPB - despite what that kind of a horseshoe would suggest in our own universe!!
  • 06-01-2013 05:18 PM
    bigentries
    Quote:

    Originally Posted by clarence View Post
    Let's be scientifically precise here. Homer has telogen effluvium - not MPB - despite what that kind of a horseshoe would suggest in our own universe!!

    No, it's MPB, he was using minoxidil

    Edit: My bad, it was dimoxinil it's evil brother that actually works
  • 06-01-2013 05:25 PM
    Arashi
    Quote:

    Originally Posted by bigentries View Post
    Remember Dolly? The human genome? they haven't really translated into new treatments. We know a lot more thanks to those achievements, but people were also expecting the first bio-engineered human to arrive in a decade at most

    That's not a fair comparison, it's more ethics that kept things back. Scientists are now able to flip on/off any gene in ANY organism, including humans (which IS being done as we speak, for example in a phase II clinical trial to make humans resistant against HIV/AIDS, see http://www.sangamo.com/pipeline/sb-728.html for example). And cloning humans is theoretically possible as well. It's just ethics keeping that back.
  • 06-01-2013 05:30 PM
    Buster
    Quote:

    Originally Posted by clarence View Post
    Let's be scientifically precise here. Homer has telogen effluvium - not MPB - despite what that kind of a horseshoe would suggest in our own universe!!

    Actually he ripped out his own hair each time Marge told him she was pregnant.
    http://i.imgflip.com/1rzub.gif
  • 06-01-2013 05:30 PM
    ryan555
    Anyone who was expecting Histogen to grow thick hair on a bald scalp is delusional. Such a treatment may never exist. However, it clearly seems that HSC is, at the very least, capable of halting hair loss without the side effects of currently available medications. It also appears that it is effective at thickening native hair and even achieving some regrowth. And instead of taking a pill or slathering some gunk on your head every day, you might be able to take this treatment only once or twice a year. That's a pretty big deal.

    As for the people freaking out about the price, this would probably end up being a product like botox - you go in once or twice a year and get a little touch up and then you're done. Like botox, it's not going to be super cheap but it's also not going to be prohibitively expensive. And no, you won't have to travel to their lab to get injections - they'll probably be in every dermatologist office on the planet, along side the botox, the fillers, etc.
  • 06-01-2013 05:36 PM
    bigentries
    Quote:

    Originally Posted by Buster View Post
    Actually he ripped out his own hair each time Marge told him she was pregnant.
    http://i.imgflip.com/1rzub.gif

    I guess as a kid (with full density) was unable to appreciate the beauty of NW3 Homer
  • 06-01-2013 05:37 PM
    Phatalis
    Quote:

    Originally Posted by ryan555 View Post
    Anyone who was expecting Histogen to grow thick hair on a bald scalp is delusional. Such a treatment may never exist. However, it clearly seems that HSC is, at the very least, capable of halting hair loss without the side effects of currently available medications. It also appears that it is effective at thickening native hair and even achieving some regrowth. And instead of taking a pill or slathering some gunk on your head every day, you might be able to take this treatment only once or twice a year. That's a pretty big deal.

    As for the people freaking out about the price, this would probably end up being a product like botox - you go in once or twice a year and get a little touch up and then you're done. Like botox, it's not going to be super cheap but it's also not going to be prohibitively expensive. And no, you won't have to travel to their lab to get injections - they'll probably be in every dermatologist office on the planet, along side the botox, the fillers, etc.

    If this is what it comes to.. histogen simply halts hair loss... as good as fin without sides.. (hopefully better than fin) than in my mind it's still a huge success.

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