Desmond -- Update us on your topical fin experiment?

Hi brother I've been meaning to update everyone here on topical finasteride but never got the chance to. So here it goes:

We have been compounding topical finasteride for over a year now for a lot patients. Over this time, I've done a lot of research, so here's all you need to know. Making topical fin, CB, Minox or even RU is so easy you would not believe! All you need is:

1. Your active ingredient
2. Suitable solvent
3. Espumil foaming solution

Here's the link to Espumil:


That's all. For example to make topical fin:
Crush your Finasteride tablets
Dissolve in alcohol (solvent)
Filter using a filter paper
Add to Espumil solution
Poor into a foaming bottle.
Voila

Thats it. It works and at least 20 ppl that I personally know of are using it.

Here's a video to help you do it:



Hope that helps everyone if you have questions about calculations, how much to put in, etc let me know and I'll post a thorough step by step protocol.

Cheers,

Des

where are the after photos of this guy?

works the same as ingesting it?

Sides?

Hey Desmond ! About CB, Versapro and HRT cream is to forget ??? Espumil is a better vehicle ?? Thanks

What's the advantage here ? That you'd need to use less fin ?

does anyone know the topical ml you need to apply to inhibit a percent of serum DHT? Does it go systemic less then oral? I guess I also wonder what is the benefit to doing this work and going topical over internal?

Great, Desmond, you're here. Thanks much for the instructions. A few specific questions for you...

1. You said 20 people are using it and it works. Do you mean 20 people who had side effects on oral finasteride are using topical finasteride effectively but WITHOUT side effects? Avoiding side effects of the pill is really what we're interested in here.

2. Do you believe H&W's liposomal version makes sense, and is likely to make a difference compared to other formulations? (Particularly with regard to avoiding side effects?)


Also, this is the 2007 paper on liposomal topical finasteride that someone cited: http://www.ncbi.nlm.nih.gov/pubmed/18161632

The full paper -- which I can't make heads or tails of -- is here: https://www.scribd.com/doc/307372835...al-finasteride

Maybe someone can interpret that for us.

Does Hasson & Wong have topical propecia? Will they precribe it to patients who have not had a hair transplant? And anyone out there who cut propecia in a half dose everyday 0.5mg per day instead of 1.0 mg.

Desmond!!! Thank goodness you are back man. I really missed you posting on here! Anyway, I have a question. I had terrible side effects when I used finasteride. Do you think that this topical finasteride would give me the same side effects?

Wouldn't something like this increase the absorption of topical finasteride into the bloodstream since finasteride is already lipophilic? Also, any indication that this would be available to consumers and not just pharmacists? This is the first time I'm hearing about this.

Okay guys, let me blow your minds with the information we dug up and presented to the dermatologists in our area! Back in 1995 when Merck was testing Finasteride for AGA, they also ran a small trial of 52 patients using very low-dose topical finasteride! This trial used Finasteride in 0.005% concentration and ran for 16 months! Can you believe it! It was minuscule doses and guess what happened

This study was later published in 1997 and is titled:

Topical finasteride in the treatment of androgenic alopecia. Preliminary evaluations after a 16-month therapy course



The size of the balding reduced, terminal hair count increased while in the placebo group it all went to negatives. Surprise surprise. They even collected plasma DHT level data and it was barely changed but the hairloss improved.

Now I don't why the topicals since then were being prepared in 1% concentrations which is higher than the oral dose you take but that is most probably why ppl experience sides even on topical fin.

For those that don't know I am a compounding pharmacist and we have patients using topical fin in many different strengths ranging from 0.05% all the way to 0.1% and they all seem to be happy with it.

So don't lose hope. Finasteride may still be a viable option for you. You just have to go down the topical route in very low doses.

Sorry I meant between 0.005% to 0.1% Missed a zero there LOL

Now with regards to liposomal delivery. That is very interesting indeed. If you are able to get it then by all means go ahead and try it. Unfortunately as far as I'm aware liposomal drug delivery is a very complicated process and can not be made in a compounding pharmacy. If you can't access that then go right ahead and try this method instead.

Cheers,

Des.