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Guys roaccutane treatment played with our retinoids receptors, it's mega highdose of vitamin A that change things in our body for life
Now look a study presentation from researchers at the " 2015 North American Hair Research Society Scientific Meeting" :
Alterations of vitamin A metabolism and signaling in central, centrifugal, cicatricial alopecia patients
CCCA: Central Centrifugal Cicatricial Alopecia (CCCA) is a form of scarring alopecia on the scalp that results in permanent hair loss. Hair loss is slowly progressive. While some persons do not have symptoms, tenderness, itch and burning are common. Hair breakage may also be an early sign of CCCA.
Histopathology reveals a lymphocytic inflammatory infiltrate (inflammatory cells) around the infundibulum (base of the hair follicle), and fibrosis (scarring). Premature desquamation (peeling) of the inner root sheath is a common feature.
this study also talk about CCCA when retinoid metabolism is altered:
Guys we have this ****in shit!!!Maybe in combination with some AGA, but we definitly have to fight against this CCCA.
On a webiste, They say as we don't know the cause, there's not targeted treatment for CCCA, but here are some of treatments:
Treatment options for CCCA include anti-inflammatory agents such as:
◾Potent topical steroids (eg clobetasol) or intralesional steroids
◾Calcineurin inhibitors: tacrolimus ointment, pimecrolimus cream
◾Tetracyclines (eg doxycycline 100 mg twice daily, taken for several weeks to months)
◾Hydroxychloroquine
◾Ciclosporin.
But in our case we know that our CCCA comes from altered retinoid receptors, so maybe we can find a more targeting strategy
Well it's complete new world, we need to help each others guys, if you who also think like me that our altered retinoid metabolism REALLY HAVE AN IMPACT OUR HAIR LOSS. And try to inhibite the consequences.
The study is clear and comes from high researchers:
Alteration of vitaminA metabolism= CCCA!!!
I believe them , we need to do something!
Now look a study presentation from researchers at the " 2015 North American Hair Research Society Scientific Meeting" :
Alterations of vitamin A metabolism and signaling in central, centrifugal, cicatricial alopecia patients
CCCA: Central Centrifugal Cicatricial Alopecia (CCCA) is a form of scarring alopecia on the scalp that results in permanent hair loss. Hair loss is slowly progressive. While some persons do not have symptoms, tenderness, itch and burning are common. Hair breakage may also be an early sign of CCCA.
Histopathology reveals a lymphocytic inflammatory infiltrate (inflammatory cells) around the infundibulum (base of the hair follicle), and fibrosis (scarring). Premature desquamation (peeling) of the inner root sheath is a common feature.
this study also talk about CCCA when retinoid metabolism is altered:
Guys we have this ****in shit!!!Maybe in combination with some AGA, but we definitly have to fight against this CCCA.
On a webiste, They say as we don't know the cause, there's not targeted treatment for CCCA, but here are some of treatments:
Treatment options for CCCA include anti-inflammatory agents such as:
◾Potent topical steroids (eg clobetasol) or intralesional steroids
◾Calcineurin inhibitors: tacrolimus ointment, pimecrolimus cream
◾Tetracyclines (eg doxycycline 100 mg twice daily, taken for several weeks to months)
◾Hydroxychloroquine
◾Ciclosporin.
But in our case we know that our CCCA comes from altered retinoid receptors, so maybe we can find a more targeting strategy
Well it's complete new world, we need to help each others guys, if you who also think like me that our altered retinoid metabolism REALLY HAVE AN IMPACT OUR HAIR LOSS. And try to inhibite the consequences.
The study is clear and comes from high researchers:
Alteration of vitaminA metabolism= CCCA!!!
I believe them , we need to do something!
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