N2c creme for hair regrowth

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  • doke
    Senior Member
    • Jun 2009
    • 1464
    #1

    N2c creme for hair regrowth

    Hi guys I have a chance to buy n2c crème for male and female hair regrowth but wonder if im just wasting my money its based on improving collagen and say after a week you will see some improvement and the 100ml bottle should last up to 90 days depending how much you need to use.
    You apply once a day at night and need to use a mild soap shampoo but I would use a sulphate free if I was to try it.
    Its priced at 75 eus including post to uk the link is here www.n2c.world/international I have been sent a brochure and the hair regrowth looks good.
    Tags: None
    • Seuxin
      Senior Member
      • Jan 2014
      • 223
      #2
      Hello,

      I'm actually testing this cream. I begun, march, 29 !
      Will provide news...If any !

        Comment

        • johnnyboots
          Senior Member
          • Feb 2011
          • 143
          #3
          Originally posted by Seuxin
          Hello,

          I'm actually testing this cream. I begun, march, 29 !
          Will provide news...If any !
          Can we get it shipped to USA?

            Comment

            • champpy
              Senior Member
              • Apr 2015
              • 336
              #4
              I dont think this was translated, but it sure does read bad

              "If the person with a balding head is not too old, his/her hair roots are in place and the hair skin can only support the hair to a fluffy size"

              I dont know how much faith id put in a product that uses this sentence in their advertising

                Comment

                • cardib
                  Senior Member
                  • Jan 2016
                  • 128
                  #5
                  immmm., i dont see how improved collagen leads to growth of hair. and plant extracts....come the fuk on, what does that even mean? sounds like snake oil

                    Comment

                    • NeedHairASAP
                      Senior Member
                      • Jul 2011
                      • 1408
                      #6
                      Originally posted by cardib
                      immmm., i dont see how improved collagen leads to growth of hair. and plant extracts....come the fuk on, what does that even mean? sounds like snake oil
                      Actually there is a lot of recent research that says collagen plays a roll.

                      The question is (1) does this actually help with collagen and (2) is a "better" collagen situation for your scalp enough to outweigh the other factors trying to destroy your hair.

                      You need both 1 and 2 to be true for this to work...


                      Science. 2016 Feb 5;351(6273):aad4395. doi: 10.1126/science.aad4395. Epub 2016 Feb 4.
                      Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis.
                      Matsumura H1, Mohri Y1, Binh NT2, Morinaga H1, Fukuda M1, Ito M3, Kurata S4, Hoeijmakers J5, Nishimura EK6.
                      Author information

                      Abstract
                      Hair thinning and loss are prominent aging phenotypes but have an unknown mechanism. We show that hair follicle stem cell (HFSC) aging causes the stepwise miniaturization of hair follicles and eventual hair loss in wild-type mice and in humans. In vivo fate analysis of HFSCs revealed that the DNA damage response in HFSCs causes proteolysis of type XVII collagen (COL17A1/BP180), a critical molecule for HFSC maintenance, to trigger HFSC aging, characterized by the loss of stemness signatures and by epidermal commitment. Aged HFSCs are cyclically eliminated from the skin through terminal epidermal differentiation, thereby causing hair follicle miniaturization. The aging process can be recapitulated by Col17a1 deficiency and prevented by the forced maintenance of COL17A1 in HFSCs, demonstrating that COL17A1 in HFSCs orchestrates the stem cell-centric aging program of the epithelial mini-organ.
                      Copyright © 2016, American Association for the Advancement of Science.





                      J Invest Dermatol. 2015 Oct;135(10):2358-67. doi: 10.1038/jid.2015.187. Epub 2015 May 19.
                      Lack of Collagen VI Promotes Wound-Induced Hair Growth.
                      Chen P1, Cescon M1, Bonaldo P1.
                      Author information

                      Abstract
                      Collagen VI is an extracellular matrix molecule that is abundantly expressed in the skin. However, the role of collagen VI in hair follicle growth is unknown. Here, we show that collagen VI is strongly deposited in hair follicles, and is markedly upregulated by skin wounding. Lack of collagen VI in Col6a1(-/-) mice delays hair cycling and growth under physiological conditions, but promotes wound-induced hair regrowth without affecting skin regeneration. Conversely, addition of purified collagen VI rescues the abnormal wound-induced hair regrowth in Col6a1(-/-) mice. Mechanistic studies revealed that the increased wound-induced hair regrowth of Col6a1(-/-) mice is triggered by activation of the Wnt/β-catenin signaling pathway, and is abolished by inhibition of this pathway. These findings highlight the essential relationships between extracellular matrix (ECM) and hair follicleregeneration, and suggest that collagen VI could be a potential therapeutic target for hair loss and other skin-related diseases.

                        Comment

                        • rbrown
                          Member
                          • Feb 2013
                          • 61
                          #7
                          I have read in this forum that every single hair (follicle included) should be considered as a single human organ. Maybe there is a cream out there that can grow human organs but i haven't heard of it. So my hopes are on stem cells or 3D printings. Creams and shampoos might help with the blood circulation on your skull but so far they have failed to treat hair loss.

                            Comment

                            • nobs
                              Member
                              • Mar 2016
                              • 30
                              #8
                              My experience has been that anything "natural" marketed towards hairloss is usually a scam or will do almost nothing to improve your hairloss situation. I've tried pretty much the whole kitchen sink in regards to hairloss including saw palmetto, topical saw palmetto, green tea, topical green tea extract, beta sitosterol, curcumin, biotin, carnitine, you name it. Also, anything with one study that was performed in India under lousy controls posted on pubmed is not enough proof that something works.

                                Comment

                                • doke
                                  Senior Member
                                  • Jun 2009
                                  • 1464
                                  #9
                                  Originally posted by Seuxin
                                  Hello,

                                  I'm actually testing this cream. I begun, march, 29 !
                                  Will provide news...If any !
                                  Hi Seuxin is the cream greasy? and how are you using it as I wonder if you use with oral finasteride you may get increased results.

                                    Comment

                                    • doke
                                      Senior Member
                                      • Jun 2009
                                      • 1464
                                      #10
                                      Originally posted by NeedHairASAP
                                      Actually there is a lot of recent research that says collagen plays a roll.

                                      The question is (1) does this actually help with collagen and (2) is a "better" collagen situation for your scalp enough to outweigh the other factors trying to destroy your hair.

                                      You need both 1 and 2 to be true for this to work...
                                      Many thanks for your info on collagen I think L Oreal did some work on this.

                                        Comment

                                        • doke
                                          Senior Member
                                          • Jun 2009
                                          • 1464
                                          #11
                                          Originally posted by johnnyboots
                                          Can we get it shipped to USA?
                                          Hi Johnny you should go to n2c web site and phone one of the numbers I in uk contacted the Netherlands number and ordered through paypal.

                                            Comment

                                            • doke
                                              Senior Member
                                              • Jun 2009
                                              • 1464
                                              #12
                                              Just a note why not wait before buying the cream to see how we get on with it unless you really do not mind a gamble which over the years we all have been sucked into stuff that does not do a lot.
                                              As I have ordered mine I am still sceptical it will work but never say never as only trying it will convince me and if I do get some results you can trust I will tell you straight away.
                                              In the brochure it says you should see something in just a week of using as I have been slowly been receading over many years and maybe in the advanced stage of mpb then if I see anything it would be a miracle haha but as said you never know.

                                                Comment

                                                • Seuxin
                                                  Senior Member
                                                  • Jan 2014
                                                  • 223
                                                  #13
                                                  Hello guys,

                                                  The cream is not greasy and nice to apply. Btw, i apply just on my bald temples.
                                                  No, i don't use topical finasteride, i use oral finasterid.
                                                  I'm day 14, will do pictures soon and compare with zoom...

                                                    Comment

                                                    • Futurocabeludo
                                                      Member
                                                      • Oct 2014
                                                      • 86
                                                      #14
                                                      I've ordered mine.

                                                        Comment

                                                        • allTheGoodNamesAreTaken
                                                          Senior Member
                                                          • Aug 2015
                                                          • 330
                                                          #15
                                                          Originally posted by Futurocabeludo
                                                          I've ordered mine.
                                                          I thought you were pushing a product you were adamant was working a few months or a year ago...

                                                            Comment

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