Safe to Drink Red Wine while on Finasteride? - Bald Truth Talk - Hair Loss, Hair Transplant and Hair Restoration Community

iwannakeephair1674

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Safe to Drink Red Wine while on Finasteride?

05-30-2012, 08:54 PM

The following link shows that red wine can inhibit CYP3A4 enzyme, similar to the way grapefruit juice does (only not as much). Is it truly safe to take Finasteride and to enjoy a small glass of dry red wine once a day?

Mechanism-based inactivation of human cytochrome P450 3A4 by grapefruit juice and red wine - PubMed

http://www.ncbi.nlm.nih.gov/pubmed/9496718

Grapefruit juice is well documented to cause clinically significant increases in the plasma concentrations of many therapeutic agents. These interactions are believed to be mediated via inhibition of intestinal cytochrome P-450 3A4 (CYP3A4) by flavonoids and/or other chemicals in grapefruit juice, a …

Also, I've read that Ketoconazole inhibits CYP3A4 enzyme too. I wonder how much is absorbed into your body when you use a 1mm scalp roller before you use Nizoral 2%.
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