PGD2 or DHT

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  • gutted
    replied
    Originally posted by Aston
    It is a fact that it causes hair loss, but their hypothesis's for why it happens are rubbish, according to what i know. Plus that looks like a typical snake oil site. They are exploiting a fact by providing a guess-level explanation and selling random products.

    It is also a fact that dietary cholesterol doesn't generally raise your cholesterol.





    I am currently eating liberal amounts of meat and butter every day and my cholesterol is lower than it was when i was avoiding it like the plague.
    Therefore, there is no "paradox", as they tout. Low cholesterol levels diminish the production of the upstream metabolites (cortisol and prog), while specialized tissues like hair follicles and the prostate convert all the T they can get into DHT without brakes, despite the increasing amounts of serum E2 the organism releases to compensate. (The imbalance comes from the difference between serum molecules (cortisol and preg) and locally produced DHT. Low cholesterol reduces serum hormones more than the locally produced ones.)
    im aware the body produces its own cholesterol, and any dietery cholesterol would result in lower amounts of the bodies own endegonous production of cholesterol to maintain the balance.

    However, beta sitosterol/niacin is another drug that is used to lower cholesterol also.

    When i was on them both i experienced hair loss in the mpb regions and the typical mpb itch. This is fact. Im thinking 5 alpha reductase enzymic activity was very high for some reason.

    cholesterol lowering drugs - statins, also have a side effect of hair loss.

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  • Aston
    replied
    Originally posted by gutted
    any thoeries as to why lowering cholesterol via cholesterol lowering drugs would cause hair loss? this is fact.
    It is a fact that it causes hair loss, but their hypothesis's for why it happens are rubbish, according to what i know. Plus that looks like a typical snake oil site. They are exploiting a fact by providing a guess-level explanation and selling random products.

    It is also a fact that dietary cholesterol doesn't generally raise your cholesterol.





    I am currently eating liberal amounts of meat and butter every day and my cholesterol is lower than it was when i was avoiding it like the plague.
    Therefore, there is no "paradox", as they tout. Low cholesterol levels diminish the production of the upstream metabolites (cortisol and prog), while specialized tissues like hair follicles and the prostate convert all the T they can get into DHT without brakes, despite the increasing amounts of serum E2 the organism releases to compensate. (The imbalance comes from the difference between serum molecules (cortisol and preg) and locally produced DHT. Low cholesterol reduces serum hormones more than the locally produced ones.)

    Leave a comment:


  • 2020
    replied
    hair loss is not the same as MALE PATTERN hair loss.... no drug can actually cause MPB

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  • gutted
    replied
    Originally posted by Aston
    I am pretty sure all of their hypothesis's are rubbish, but yeah, the link is there.
    The key is in the production rates. Cholesterol first goes into supporting the cortisol line. If that isn't being handicapped by the thyroid activity, it counteracts DHT.
    any thoeries as to why lowering cholesterol via cholesterol lowering drugs would cause hair loss? this is fact.

    they state at the bottom of the page -

    "There is a real paradox with anti-cholesterol agents. Some can lead to side effects at scalp level: irritations, pruritus, itchiness and… hair loss ! "

    this is also experienced with mpb.

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  • Aston
    replied
    I am pretty sure all of their hypothesis's are rubbish, but yeah, the link is there.
    The key is in the production rates. Cholesterol first goes into supporting the cortisol line. If that isn't being handicapped by the thyroid activity, it counteracts DHT.

    Leave a comment:


  • gutted
    replied

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  • 2020
    replied

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  • Kirby_
    replied
    Originally posted by gutted
    yeah i know these people are brainwashed.

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  • gutted
    replied
    Originally posted by 2020
    I'm almost positive that the number of seb glands gets to be ACQUIRED from PGD2 or whatever and not your genetics. You didn't have that many seb glands before you started balding...


    looool



    10char

    Leave a comment:


  • 2020
    replied
    Originally posted by gutted
    they're scalp skin make up is gentically determined to contain only a few seb glands per cm2!
    I'm almost positive that the number of seb glands gets to be ACQUIRED from PGD2 or whatever and not your genetics. You didn't have that many seb glands before you started balding...

    Originally posted by gutted
    it could also be something like those people probably having the strain of bacteria in thier intestines that produce eqoul, which help keeps dht levels homeostatic/balanced.
    didn't you say that this equol thing wouldn't work yesterday?

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  • gutted
    replied
    heres something i found that s very intresting - http://www.ncbi.nlm.nih.gov/pubmed/12581424

    it probably explains why nw7's are able to achieve regrowth with benaxoprofen.

    it slowly repairs the scarring.
    i wouldnt be surprised if blocking cox2 is the answer to scarless healing.

    Leave a comment:


  • gutted
    replied
    Originally posted by 2020
    what people? Me? How are we brainwashed? There is just too much evidence suggesting that lifestyle has no impact on MPB whatsoever...

    I said this before: WHEN ALL YOU HAVE IS A HAMMER, EVERYTHING LOOKS LIKE A NAIL.
    You people think everything causes MPB... ****'s sake there is actually a discussion on IH forums going on right now that discusses HOW OCEAN WATER HELPS REGROW HAIR... SERIOUSLY
    lifestyle probably causes many many diseases, the thing with getting evidence to support lifestyle is the cause of these diseases is very very hard to do. how would you do it???

    anyway get back to topic, this thread aint about diet.

    Leave a comment:


  • gutted
    replied
    Originally posted by 2020
    ok so what's the non-genetic secret that lets those millions of extremely unhealthy people keep their hair?
    lol what dont you understand what im saying?

    they're scalp skin make up is gentically determined to contain only a few seb glands per cm2!


    it could also be something like those people probably having the strain of bacteria in thier intestines that produce eqoul, which help keeps dht levels homeostatic/balanced.

    Leave a comment:


  • 2020
    replied
    Originally posted by gutted
    intresting diagram.

    yeah i know these people are brainwashed.
    what people? Me? How are we brainwashed? There is just too much evidence suggesting that lifestyle has no impact on MPB whatsoever...

    I said this before: WHEN ALL YOU HAVE IS A HAMMER, EVERYTHING LOOKS LIKE A NAIL.
    You people think everything causes MPB... ****'s sake there is actually a discussion on IH forums going on right now that discusses HOW OCEAN WATER HELPS REGROW HAIR... SERIOUSLY

    Leave a comment:


  • gutted
    replied
    Originally posted by Aston
    Just notice how cholesterol is the starting point of steroid production. http://upload.wikimedia.org/wikipedi...enesis.svg.png

    And that representation is grossly incomplete!

    Also, it's useless to reply to 2020's troll posts...
    Some people can only understand one concept at a time. If you mention diet and metabolism, genetics cease to exist and every fat guy becomes a perfect way to debunk actual logic. Either that or someone's paying them.

    Edit: mineral deficiencies can cause a decrease in hormone production as well (Zinc is the famous one). You can eat the perfect USDA healthy diet and have leaky gut (due to grain toxins) and therefore chronic inflammation and autoimmune disorders, coupled with mineral deficiency due to soil depletion and low cholesterol due to the nutritionist scare...
    intresting diagram.

    yeah i know these people are brainwashed.

    Leave a comment:

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