RU58841 Warning

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  • doke
    replied
    Originally posted by medicalknowhow
    That's a fair point; I wasn't aware there were similar reports. These topical substances that are touted online as to not go systemic, clearly go systemic in at least some users, with literal physical evidence, the least of which is libido alteration. Take care in any case. Cheers
    Many thanks i do not like any of the hair loss drugs but some become so desperate depressed that they will try anything that they read about with some hope of saving or regrowing there hair i still do myself and after many years of trying natural and the topical drugs there is still no miracle out there.
    Not sure if the new BIOSCALIN Attivatore Capillare iSFRP-1 - Hair loss treatment that you apply i think once a week is any good this italian company also has a natural men's energy topical that you use every other day as well, although after the Trinov let down i am not sure if its worth spending money on this product although once a week sounds good if it works that is.

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  • medicalknowhow
    replied
    Originally posted by doke
    There are those who have had the same symptoms with topical minoxidil as well and reported deaths on this substance i would use ru topical anyday to minoxidil as that did make my face bloat and above symptoms you state including headaches dizzy spells.
    That's a fair point; I wasn't aware there were similar reports. These topical substances that are touted online as to not go systemic, clearly go systemic in at least some users, with literal physical evidence, the least of which is libido alteration. Take care in any case. Cheers

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  • doke
    replied
    There are those who have had the same symptoms with topical minoxidil as well and reported deaths on this substance i would use ru topical anyday to minoxidil as that did make my face bloat and above symptoms you state including headaches dizzy spells.

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  • medicalknowhow
    replied
    Originally posted by doke
    I to be honest think your talking nonsense many people on the forums have been using it for many years with no problems and it states that topical use is not systemic this scary nonsense came out about finasteride and dutasteride and to be honest i had more problems with them two drugs orally than topical ru i even tried using topical 2% flutamide when it was available and again right as rain.
    On hair loss web sites loads of scary things have been said with no back up proof.
    People have also been using it and getting heart palpitations, which makes what you just wrote, meaningless. People who have not reported heart problems also have no proof that they aren't doing silent damage; nobody knows, it was never tested properly. RU is over one order of magnitude more potent then all of the substances you just listed, even if you combined them together, so no, a kid licking your head is not at risk in even remotely the same way as they are with RU. Going by anecdotal accounts on internet forums, which is all we have, it is a minority whom have cardiac effects and those who take more than 50mg per day are the bulk of that minority. Anyways, just want to know people are aware of the risks they are taking and not blindly following posts from "Bro scientists" on Bro-science forums. I was a clinical E.P. before taking my new job in 2015, not that it's relevant to unresearched, untested substances not approved for humans and only glazed over two decades ago. Take care in any case. This year was rough.

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  • doke
    replied
    By the way even used 8% topical with no problems but i would not suggest anyone licks your head even with minoxidil in some strengths that you can buy up to 15% which to tell you the truth i would not use only 2-5% the most.

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  • doke
    replied
    I to be honest think your talking nonsense many people on the forums have been using it for many years with no problems and it states that topical use is not systemic this scary nonsense came out about finasteride and dutasteride and to be honest i had more problems with them two drugs orally than topical ru i even tried using topical 2% flutamide when it was available and again right as rain.
    On hair loss web sites loads of scary things have been said with no back up proof.

    Leave a comment:


  • medicalknowhow
    replied
    Originally posted by doke
    These drugs are for research purposes and you use at your own risk i have as sad used ru and also tried spiro topical but finasteride used to be unlicensed in uk for hair loss but i was using it as proscar many years before it was released the only reason that ru failed to come onto the market was not due to safety but the huge costs involved and a takeover of the french pharma and when finasteride came on sale as 1mg the company did not know if they would recoup there costs i have not seen any of the trials on topicals causing harm i believe one person died on topical minoxidil but they may have already died anyway.There was a guy on the hairloss sites that tried oral flutamide and he found he could hardly crawl to the bathroom but he was silly to take that orally.
    When Brian shelton vip was on the forums many years ago we all talked about topical ru and flutamide and he knew a lot about hairloss and the drugs he said that ru was the mother of all antiandrogens like flutamide is but without the systemic side affects.
    But there again its only for your own research purpose and you use it or leave it as said i used it and had no problems and in fact i am in my 60s now and would not hesitate to start back on it and i will say its safer topically than oral dutasteride and finasteride.
    It was not just a financial issue -- it is so much stronger than the other substances you mention that they are not even remotely comparable. If you go systemic with RU, there is no way to even tell what damage you can do, hence it's a gamble, like everything. It would not be allowed in homes because a child licking their hands after touching your head (something that happens all the time in real life) would be a lawsuit waiting to happen. People are not imagining their heart palpitations, people are abusing substances that are not tested properly on humans... it was tested 20 years ago, twice, and that's all. Not everyone is effected, but everyone is roling the dice.

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  • doke
    replied
    These drugs are for research purposes and you use at your own risk i have as sad used ru and also tried spiro topical but finasteride used to be unlicensed in uk for hair loss but i was using it as proscar many years before it was released the only reason that ru failed to come onto the market was not due to safety but the huge costs involved and a takeover of the french pharma and when finasteride came on sale as 1mg the company did not know if they would recoup there costs i have not seen any of the trials on topicals causing harm i believe one person died on topical minoxidil but they may have already died anyway.There was a guy on the hairloss sites that tried oral flutamide and he found he could hardly crawl to the bathroom but he was silly to take that orally.
    When Brian shelton vip was on the forums many years ago we all talked about topical ru and flutamide and he knew a lot about hairloss and the drugs he said that ru was the mother of all antiandrogens like flutamide is but without the systemic side affects.
    But there again its only for your own research purpose and you use it or leave it as said i used it and had no problems and in fact i am in my 60s now and would not hesitate to start back on it and i will say its safer topically than oral dutasteride and finasteride.

    Leave a comment:


  • medicalknowhow
    replied
    Originally posted by doke
    Hi guys i remember in the 90s before finasteride became available a mens hair magazine editor said that finasteride was so dangerous as men were using it off label and after many years many men have been using minoxidil and getting side affects as we know it was a blood pressure drug made from rats urine, now ru was tested on humans but did not come to market but it was tested alongside topical flutamide that was systemic unless he sintov gel was used and ru was said to be non systemic and safe in topical form i have used it with no problems but i think the the problem is lack of available tested product as we do not know what is in a premade or the powder although its supposed to be 99% pure but that is still not proof to me.
    I think it was more about finance and that finasteride came onto the market it was tested on humans and it was not safety why it did not come to market as the french company got taken over and i think another pharma company has it now.As a non steroidal drug its safe but any drug could cause side affects i ingested as said i myself am not using it now but would still use in the future until a new topical antiandrogen becomes available by the way i think some complained that eucapil caused them side affects we know that finasteride does orally in some.
    The two Human trials were almost 20 years ago. There is a reason it is not intended for Human use. Find someone online unlucky enough to have the sudden onset chest pains and high blood pressure/palpitations and then send them a message months later -- you will find that "zero" of them ever recovered. I have asked users over one year past their cessation date and they are unchanged and merely "learned to live with it" so the palpations become "the new normal". Doctors have no course of action for this undocumented and unresearched chemical castration of the heart tissue via receptor blockage. Reality is tough. It looks safe on paper, to idiots. To people who aren't idiots, it looks like a gamble, at best, where you won't know if your heart will bug out or not until you try, while morons write "but I've been using it for 3 years and only my pee pee doesn't work, my heart is fine".

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  • doke
    replied
    Hi guys i remember in the 90s before finasteride became available a mens hair magazine editor said that finasteride was so dangerous as men were using it off label and after many years many men have been using minoxidil and getting side affects as we know it was a blood pressure drug made from rats urine, now ru was tested on humans but did not come to market but it was tested alongside topical flutamide that was systemic unless he sintov gel was used and ru was said to be non systemic and safe in topical form i have used it with no problems but i think the the problem is lack of available tested product as we do not know what is in a premade or the powder although its supposed to be 99% pure but that is still not proof to me.
    I think it was more about finance and that finasteride came onto the market it was tested on humans and it was not safety why it did not come to market as the french company got taken over and i think another pharma company has it now.As a non steroidal drug its safe but any drug could cause side affects i ingested as said i myself am not using it now but would still use in the future until a new topical antiandrogen becomes available by the way i think some complained that eucapil caused them side affects we know that finasteride does orally in some.

    Leave a comment:


  • medicalknowhow
    replied
    Originally posted by telogen
    I've been doing RU continuously for almost 3 years. Majority high dosages 100mg+.
    I've only experienced drop in libido and weaker ejeculation, which is expected when blocking your DHT. Heart failure and lung scarring sounds like pure scaremongering from guys too afraid of using the drug.
    You're a moron. I dissected cadavers for six years at a research institute in Sydney just to give you an idea. "Guys too afraid of using the drug" -- please don't breed. RU is one of the most dangerous drugs in its class, hence it was immediately banned, because having it in a household setting where children could put their hands in their mouth after touching "daddies head" would have entirely unknown consequences. Even when symptoms are silent or "only libido" it is still blocking the respiration of cells. You clearly have no idea how cardiomyocytes work or what they are, so please, punch yourself in the face. Yes, RU directly causes "most likely" irreversible heart damage for which there is no treatment, because it is not mechanical ischemia. Once you alter the function of the heart at a chemical level in such an acute fashion with such a strong compound, there is no mechanism for it to "bounce back". You can take RU at 50mg per day for years and not know you're killing heart cells and altering ventricular function, or you can have a genetic expression that hides the damage you've done. For saying what you said, you are a waste of space and you know bugger all about human physiology. Kindly go F yourself.

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  • medicalknowhow
    replied
    Originally posted by brazil123
    Hello “helpneeded”! Did you find and solution? I would like to know if there’s any news on your case, because i have been experiencing some chest discomfort and also hypertension. Please contact me and lets help each other. I can send you my e-mail if you want to
    Hi brazil123; hope you are doing ok -- My "friend's rat" accidentally ingested a small amount of RU but didn't think anything of it, due to the short half-life (this was a silly conclusion as once it reaches "all associated" receptors on a systemic level, nobody has data on how fast the damage is done to heart tissue and how severe it is) he was also using 1ml per day at 5% concentration for 2 years... Within a few days of the accident, his blood pressure went into the hypertensive zone and never recovered. Heart palpitations made sleep extremely difficult from that day on into perpetuity. He didn't realise it was due to the accident until having a "lightbulb" moment a week after he was not able to sleep, and had a dental surgery appointment where they informed him his blood pressure was way above his usual (he was always 117-124/78 before this, every time, like clockwork and 138-147/94 from then on after) There was no resolution and the damage appears to be permanent. He was in perfect health with mandatory physicals every 12 months due to occupation, right up unto the accident. His resting heart rate immediately changed from 52 to 60 and stayed at that new level. Did your heart condition continue for the past few months? I'm assuming yes, as the last person I discussed the case with has had heart palpitations for the 6 months following cessation of the RU and no sign of improvement, they merely grew accustomed to their palpitations. People don't believe it can do this because they're uninformed. Heart palpitations are well reported at varying doses, and now the cases where seemingly permanent damage occurs have been made apparent.

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  • brazil123
    replied
    Originally posted by Helpneeded
    Hi guys,

    After taking Ru 3 times I seem to be experiencing cheat pains/discomfort, shortness or breath, fatigue and sternum/back aches. Symptoms seem to come and go. I rush to hospital twice on the weekend and did an EGC, ECHO, xray and blood test all pass all test. I have no history of anxiety or stress or hypochondriac nature …or any family history of heart problems … I also visited a cardiologist and he couldn't find anything... which seems to be a theme with other customer who've taken RU. I want to ensure I don't cause any long term heart problems, so I'm writing to here to ask and warn people who have been on or thinking about taking RU : (….

    HELP---I really do need help here, can any one who has taken RU advise or someone in the medical field familiar with Androgen blockers advise how I can remedy the side effects asap as I don't want any long term health issues.
    Hello “helpneeded”! Did you find and solution? I would like to know if there’s any news on your case, because i have been experiencing some chest discomfort and also hypertension. Please contact me and lets help each other. I can send you my e-mail if you want to

    Leave a comment:


  • brazil123
    replied
    Hello “helpneeded”! Did you find and solution? I would like to know if there’s any news on your case, because i have been experiencing some chest discomfort and also hypertension. Please contact me and lets help each other. I can send you my e-mail if you want to

    Leave a comment:


  • doke
    replied
    In the trials of ru58841 topical it was said there was no systemic affects that's why it was it was considered safe other anti androgen's such as topical flutamide were systemic in there actions.

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