Where are the phase IIb results for Bimatoprost?

[luca10]

It would be the happiest day of my life

[It's2014ComeOnAlready]

You guys are going to think I'm nuts, but I'm starting to wonder if Allergan is going to announce bim August 6th at their Q2 earnings conference call.

I say this because poster, "bornthisway" says that he heard from a dermatologists office that claims to work closely with Allergan says they plan on releasing a hair loss product based on bimatoprost as early as this summer. BiqqieSmalls is a shareholder of Allergan stock, and he spoke with Investor Relations back in May, and they said, they haven't released results, even to shareholders. The then asked then when, and they responded "in a few months." When he asked what was taking so long, they said it was because of the "complexity of bimatoprost."

I think it's possible that we might either see results, or some sort of announcement. I think they've been holding back because a) people will be trying to get their hands on it before the release b) the acquisition of Kythera and setipiprant. There is a lot going on behind the scenes, and since Allergan seems very determined to dominate medical aesthetics, they are going to want to cover the entire hair loss market by having the new minoxidil and propecia, but only more effective, and without the sides.

Keep a look out. I think it's possible.

[BiqqieSmalls]

Does anyone know when Actavis/Allergan plans to release their 2015 Q2 report?

[champpy]

I really hope this SCALP treatment they may have will do something. I for one tried the 0.03% for about 4 months and I cant really see any growth at all. Nothing significant at all, which sucked. Thought I would at lease get a few new hairs, id even settle for some vellus.

But alas , nothing.

[It's2014ComeOnAlready]

A little bit of fin (microdoses a few times a week) plus bim could go a really long way.

[Justinian]

Im worried about bim for one reason. It is a hair growth stimulant. If it works shouldnt it work to regrow hair, with or without seti? I mean i understand that these two may work better in conjunction we each other but if you are already maintaining with fin or dut, you wouldnt need seti, so why wouldnt bim alone be of some help?
Minox is sold as a growth stimulant . We use fin to help maintain that growth.
why is it bims release is dependant on seti? Sad to say but it leads me to think that bim alone is not that great afterall

Hopefully someone can set me straight on this

Bim should work alone... But think of it like this: bim is pressing the gas pedal of a car and seti is releasing the brake pedal. If you just use bim, you have the gas pedal down but the brake pedal is pressed too so you won't be going too fast.

This is just speculation from one article I read, so this analogy may or may not apply until they are tested.

[champpy]

Im worried about bim for one reason. It is a hair growth stimulant. If it works shouldnt it work to regrow hair, with or without seti? I mean i understand that these two may work better in conjunction we each other but if you are already maintaining with fin or dut, you wouldnt need seti, so why wouldnt bim alone be of some help?
Minox is sold as a growth stimulant . We use fin to help maintain that growth.
why is it bims release is dependant on seti? Sad to say but it leads me to think that bim alone is not that great afterall

Hopefully someone can set me straight on this

[It's2014ComeOnAlready]

2014, you're starting to sound like a conspiracy theorist. You can theorize all you want but none of it matters until results and/or a product is released. I'm as eager as everyone else here but we just have to sit back and wait.

LOL Yea thanks

[Hemo]

2014, you're starting to sound like a conspiracy theorist. You can theorize all you want but none of it matters until results and/or a product is released. I'm as eager as everyone else here but we just have to sit back and wait.

[It's2014ComeOnAlready]

I really wish that bim wasn't like minoxidil where you stop using and your hair just falls out lol. I don't know if this is old news or not, but I just saw my derm again two days ago and she is usually up on hair treatments and what not. She said that last she heard, there was a treatment (bim) that had good results, but the company was trying to get around the hyper pigmentation effects it had. It is known in the eye lash application, but I guess it was also affecting the scalp too.

hmm, well if it happens already with an approved drug, I wonder if it's that big of a deal. Also, I'd take hyperpigmentation on my scalp over dark circles around the eyes like you get with minox.

[It's2014ComeOnAlready]

lol 2014, I really love most of your posts. You keep the forum positive and are optimistic and I share your optimism that we will have better treatments in the future..but come on man, to suggest they already started phase III secretly is a little absurd.

Thank you, thank you lol. I'm not saying "secret," just not posted to clinicaltrials.gov for the reasons I have posted. I don't think it's that absurd. Is it really that much of a big deal not to post to a publicly accessible website? They don't need to recruit, and there is strong reason to believe their work will be stolen and/or used before it has had a chance to pass trials. There would be an incentive to omit posting in this case.

You really think the FDA would say no? They would be protecting consumers if they said yes.

[Ziggyz123]

I really wish that bim wasn't like minoxidil where you stop using and your hair just falls out lol. I don't know if this is old news or not, but I just saw my derm again two days ago and she is usually up on hair treatments and what not. She said that last she heard, there was a treatment (bim) that had good results, but the company was trying to get around the hyper pigmentation effects it had. It is known in the eye lash application, but I guess it was also affecting the scalp too.

[FearTheLoss]

lol 2014, I really love most of your posts. You keep the forum positive and are optimistic and I share your optimism that we will have better treatments in the future..but come on man, to suggest they already started phase III secretly is a little absurd.

[It's2014ComeOnAlready]

I came across an interview with David Pyott, and Jim Cramer from a few years ago, and they began talking about latisse etc. Pyott (former CEO of Allergan) said that before Latisse was even released, people were trying to get their hands on it. This would also be a problem for the mpb version.

Now, with regard to bim for the scalp - yes, in this instance, people would try and get their hands on it as well, and they could. Not only that, but as many of you know, Allergan has been in recent legal battles with companies who can make generic bim.

(I am completely speculating here, but I think I could be right in this instance)
So, to prevent people from buying this stuff themselves, or other companies/labs attempting to distribute bim at the right concentration, Allergan has kept completely quiet about the phase 2b trial. At the same time, they have quietly progressed with phase 3, and with the FDA's permission, have not posted a registered trial on clinicaltrials.gov.

I believe this is possible because they've already recruited participants from previous trials, and have the necessary amount for a phase 3 (meaning, there is no need to post as a recruitment tool). Also, this would prevent people from trying to get their hands on this drug before it came out, as well as the companies/labs who would seek to do the same. I believe this sort of arrangement could be made in this instance, in order to protect consumers from testing an unregulated chemical on themselves. I think given the FDA's stance on safety, this is a possibility. Allergan's experienced this sort of attempt with Latisse before it came out, and now that the drug is actually in the market, all the more likely and possible.

Every time, it seems when someone from a hair loss forum attempts to ask about the trial or drug, the person they speak with acts like they've never even heard of it. They're not guarding a failure. Allergan is too big of a company at this point to be afraid of a failed drug or trial.

Yes, the FDA sticks by the rules, but big pharma, and FDA work together. If a company producing a drug has very good reason (like the safety of others, and the protection of a company's ability to make money) to not post to the clinical trials website, I believe the FDA would certainly allow a small accommodation such as this.

[rdawg]

It's an interesting combination for sure, I dont think seti was what they were after as you guys have stated but was part of the package that appealed to them doing the buyout.

this is good news though, Allergans is a big, powerful company and has alot of money to fund into this stuff and BIM and Seti are two very interesting and seemingly effective products.

at the very least we get results in early 2016, but I think there will be some kind of announcement with these two in the next few months here.

All in all, nothing ultra-positive, but we at least have some reason to be optimistic and 100% big news, good or bad will be coming to us very soon with CB, SM, BIM and SETI all moving to the next phase or finishing up their next phase within the next 6 months.