We have 3 companies working on topical "side free" finasteride equivalents

[burtandernie]

It probably will but like fin its not usually the case. Stopping hair loss is the most you can count on and any growth is just a lucky bonus. Most times the regrowth is not that cosmetically significant anyways its not like most guys are jumping ahead norwood levels or anything.
I would think CB basically does the same thing, but anything is really possible until we see more. It just really hurts to think about 3 more years with just finasteride as you option for prevention

I agree about why propecia did not turn out that well and I think a topical that has no chance at sexual sides will do a lot better. I dont think the idea of taking a drug in general sits that well for most guys just to keep hair and ever that might be a losing battle long term. If CB or one of these topicals could become over the counter someday next to rogain that is the big win I think. It will be much easier to get, and the cost will come down when it sells in mass because people dont need to see a doctor to get it

[deuce]

How do we know it will not regrow hair. I have seen fin regrow hair many times, and Cb is suppose to work better than fin.

[Tenma]

There must be a reason they all go for acne first. The idea that they are literally all so retarded they haven't figured out alopecia has a market is not credible.

I suspect it is that they recognise how hard it is to get regrowth in alopecia, which makes it difficult to market. Propecia is regarded as a disappointment in terms of sales, and was so even before the sexual sides became big news. Unfortunately, "spend $100 a month to probably slow down your hair loss" just isn't a strong advertising statement.
.

I think you are spot on here. Propecia sales were/are crappy. the influence of some factors played a significant role

1. the side effects histeria
2. you could buy the generic form and save money
3. minimal regrowth

Point 1 and 2 wont be a problem for cb or sb-204.

Still, we must remember that this sort of second generation antiandrogens will be hair keepers rather than regrowers.

Topicals stopping dht effects locally are the logical next step in aga treatments. we really need them succeeding in coming to the market.

[Vox]

OMG, what the hell is it with all these biotechs being so obsessed with treatments for acne? Cosmo Pharmaceuticals did this too; acne first, hair loss later. Are they completely stupid?

No, they simply need money and the need it now.

Acne can be reasonably managed today and it affects mostly adolescents, boys and girls, which are very sensitive about their looks. On the other hand, hair loss, even in the extreme unfortunate case where it starts so early, is almost never a concern at teen age. It is also well known that hair loss is a very tough nut to crack.

Q.E.D.

[Pate]

ASC-J9 is progressing so slowly it's almost going backwards. It took 4 years just to get from Phase 2a to 2b. At that rate they'll never get to Alopecia trials. I remember it was big news on the forums in 2009 ish, but seems to have stagnated to such a point some here don't even seem to have known about it.

I think they are having problems finding a partner for it. Unsurprisingly, since the acne market is already well catered for.

There must be a reason they all go for acne first. The idea that they are literally all so retarded they haven't figured out alopecia has a market is not credible.

I suspect it is that they recognise how hard it is to get regrowth in alopecia, which makes it difficult to market. Propecia is regarded as a disappointment in terms of sales, and was so even before the sexual sides became big news. Unfortunately, "spend $100 a month to probably slow down your hair loss" just isn't a strong advertising statement.

Whereas improvement in acne actually seems to be a selling point for people. As evidenced by the fact the acne market is flooded with both products and advertising.

Oh well, we just have to accept that. Put our faith in Cosmo who are the only guys who seem both interested enough and financially powerful enough to push it through.

[HARIRI]

I believe in Finasteride efficiency in stopping hair loss and growing vellus hair too. I had most of my hair grown back in 2007 however the sexual sides killed my love life and confidence. I really wish and pray that one of these companies to successfully produce a topical Finasteride which does not cause any sexual sides. I find it hard to believe though especially that it will be absorbed by the skin into the blood. However I'm not a scientist and maybe someone over here can explain how will they manage to do it (Topical Finasteride with sexual sides)!

[hellouser]

acne already has two very good products right now benzoyl peroxide and isotretinoin. they both can cure acne. no cures for alopecia though

The fat corporate d-bags in the biotechs are borderline retarded for throwing in ANOTHER acne treatment. I wanna strangle someone right now.

[kobefan234]

OMG, what the hell is it with all these biotechs being so obsessed with treatments for acne? Cosmo Pharmaceuticals did this too; acne first, hair loss later. Are they completely stupid?

acne already has two very good products right now benzoyl peroxide and isotretinoin. they both can cure acne. no cures for alopecia though

[lilpauly]

Somebody help me find the foam for asc ! Cb blocks dht from attacking the scalp, asc completely destroys it

[hellouser]

We need it now. We are screwed without a vehicle. I expect May to be a big month with all these announcements.

I'd say DEMAND would get you further than simply expecting.

[deuce]

We need it now. We are screwed without a vehicle. I expect May to be a big month with all these announcements.

[hellouser]

Its tough to not ask yourself what took so long? Why couldnt any of these 3 treatments been started on like 5 or 10 years ago? Waiting years for any of these is a long time to watch hair die that probably wont ever come back. The idea of taking a drug like propecia really doesnt sit too well with me though and long term your just going to switch to one of those once its out anyways so why bother starting propecia? We dont know if hair saved on propecia will transfer over to whatever other thing comes out. Seems it would but who knows
Yeah though in like 5 years assuming these pan out MPB will be a much easier problem to deal with and maybe even preventable with few if any sides. Once that day happens MPB is in a sense cured for people that still have hair at least.

It most definitely will 'transfer'. Your logic would support the notion that taking finasteride for 10 years and immediately stopping would suggest that you'd immediately experience hair loss of 10 years right after quitting.

[burtandernie]

Its tough to not ask yourself what took so long? Why couldnt any of these 3 treatments been started on like 5 or 10 years ago? Waiting years for any of these is a long time to watch hair die that probably wont ever come back. The idea of taking a drug like propecia really doesnt sit too well with me though and long term your just going to switch to one of those once its out anyways so why bother starting propecia? We dont know if hair saved on propecia will transfer over to whatever other thing comes out. Seems it would but who knows
Yeah though in like 5 years assuming these pan out MPB will be a much easier problem to deal with and maybe even preventable with few if any sides. Once that day happens MPB is in a sense cured for people that still have hair at least.

[hellouser]

I notice ASC-J9 has completed phase II trials for acne. Is there a possibility the acne formulation could be used off label for hair loss?

OMG, what the hell is it with all these biotechs being so obsessed with treatments for acne? Cosmo Pharmaceuticals did this too; acne first, hair loss later. Are they completely stupid?

[Thinning@30]

I guess it is good that more companies are working on hair loss solutions.

The sad reality though is that all these things are years away from being commercialized. Also, while topical AAs might completely eliminate hair loss, I don't think they will do much for high norwoods who have already lost much of their hair. Those folks will have to wait for a stem cell solution or donor replication.

I notice ASC-J9 has completed phase II trials for acne. Is there a possibility the acne formulation could be used off label for hair loss?