Propecia erectile dysfunction effect is real folks

[Notbaldyet]

placebo

ED, ejaculatory disorders,
and decreased libido were more frequently
observed in finasteride- than placebo-treated men
(15% vs. 7%, respectively). The PREDICT trial
showed that the incidence ofEDand reduced libido
were similar between the finasteride and doxazosin
groups. In the PCPT, in which 18,882 men were
enrolled for 7 years of finasteride therapy versus
placebo, approximately 28.9% of men discontinued
therapy in the placebo group compared with 36.8%
in the finasteride group (P < 0.001). Reduced ejaculate
volume, ED, loss of libido, and gynecomastia
were more common in the finasteride group
(P < 0.001).

--
ED is highly psychological. However, the probability between effects in placebo and non placebo groups is statistically significantly different.

i must also add that gynecomastia is an objective finding.

[brentipold]

As you obviously have no substantive argument to offer beyond the ad hominem, you merit no serious attention.

There's a forum full of ppl devastated by fin.. What other reason do I need? NONE!!! Blood tests don't lie, and they disprove all of the mumbo jumbo you speak of, so do me a favor and stop talking about things you know absolutely NOTHING about.

[gmonasco]

i did. it costs $35. did you?

Indeed I did. And I noted how often subjects who were given placebos still reported problems with diminished libido or erectile dysfunction.

[gmonasco]

You're obviously one of the lucky idiots that it doesn't effect.

As you obviously have no substantive argument to offer beyond the ad hominem, you merit no serious attention.

[brentipold]

I guess not.. I guess you're the real genius around here then huh?

[Notbaldyet]

read it

i did. it costs $35. did you?

[gmonasco]

crap. its real. i can't believe i took this shit.

Here's a helpful hint: If you're going to reference a medical journal article, you should try actually reading it first.

[gmonasco]

There also tons of people waiting in the dark because they are embarrassed about the problem. its not as subjective as you may think.

You apparently don't understand the meaning of "subjective."

[Notbaldyet]

crap. its real. i can't believe i took this shit.

J Sex Med. 2010 Dec 22. doi: 10.1111/j.1743-6109.2010.02157.x. [Epub ahead of print]
Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido and Erectile Dysfunction and Depression in a Subset of Patients.
Traish AM, Hassani J, Guay AT, Zitzmann M, Hansen ML.

Departments of Biochemistry and of Urology, Boston University School of Medicine, Boston, MA, USA Center for Sexual Function/Endocrinology Lahey Clinic, Northshore, Peabody, MA, USA Centre for Reproductive Medicine and Andrology/Clinical Andrology Domagkstrasse 11 University Clinics Muenster, Germany Department of OB/GYN, Stavanger University Hospital, Stavanger, Norway.
Abstract
Introduction.  5α-reductase inhibitors (5α-RIs), finasteride and dutasteride, have been approved for treatment of lower urinary tract symptoms, due to benign prostatic hyperplasia, with marked clinical efficacy. Finasteride is also approved for treatment of hair loss (androgenetic alopecia). Although the adverse side effects of these agents are thought to be minimal, the magnitude of adverse effects on sexual function, gynecomastia, depression, and quality of life remains ill-defined. Aim.  The goal of this review is to discuss 5α-RIs therapy, the potential persistent side effects, and the possible mechanisms responsible for these undesirable effects. Methods.  We examined data reported in various clinical studies from the available literature concerning the side effects of finasteride and dutasteride. Main Outcome Measures.  Data reported in the literature were reviewed and discussed. Results.  Prolonged adverse effects on sexual function such as erectile dysfunction and diminished libido are reported by a subset of men, raising the possibility of a causal relationship. Conclusions.  We suggest discussion with patients on the potential sexual side effects of 5α-RIs before commencing therapy. Alternative therapies may be considered in the discussion, especially when treating androgenetic alopecia. Traish AM, Hassani J, Guay AT, Zitzmann M, and Hansen M. Adverse side effects of 5α-reductase inhibitors therapy: Persistent diminished libido and erectile dysfunction and depression in a subset of patients. J Sex Med **;**:**-**.

© 2010 International Society for Sexual Medicine.

[kal-el1975]

Short story on me. Started thinning at 24. Got on Propecia 1mg daily and been on it for 11 yrs. Had great results at around the 1 1/2 year mark as all thinning went away. Stayed pretty much about the same until about year ago when thinning started back up slowly.

Sides included definite decrease in libido which eventually went away after a few months of starting. Also less firm erections in my opinion. Even as recently as a few months ago when I stopped taking it for a month they got better it seemed. So gives me hope that if I do stop taking it any potential effects should go.

No major sides but it does do something to you even if you tolerate it well.

[brentipold]

There also tons of people waiting in the dark because they are embarrassed about the problem. its not as subjective as you may think.

[norc]

That's not valid reasoning, because:

a) The sample is self-selecting. People are far more likely to post about experiencing side effects than they are to post that they aren't experiencing any side effects.

b) Sexual dysfunction (the most commonly reported side effect) has a huge psychological/psychosomatic aspect to it, so one cannot validly assume that propecia users who report experiencing it are actually being physically affected by the drug in that regard.

I certainly agree with this. Reports on side effects are somewhat subjective. Is there a way to measure this objectively?

[brentipold]

People who say that its all in their head are just kidding themselves. When I had my libido, there was nothing stopping me from having or wanting sex. If someone said if you drink milk you'll get sexual side effects, it wouldnt have any affect on me neither. The whole aspect of "its all in your head" is just ridiculous and those who don't experience the side effects cant speak to any of this because they arent affected by it.

[Thinning@30]

I've stated this in other threads, but personally, I think that Propecia's sexual side effects are underreported for the following reasons:

1. Most Propecia users are men who are taking it for prostate problems rather than MPB. These men tend to be older, in many cases past their sexual primes, so they are probably less likely to notice a decrease in sexual performance. If they do, they may falsey attribute it to general ageing, or to whatever other medications/medical problems they have rather than the Propecia. Older men who are using Propecia for MPB may do the same.

2. Sexual dysfunction is a very emotional subject. My guess is that most men are loathe to admit to any decline in performance, even to themselves. Furthermore, it is an extremely awkward thing to discuss, even in a confidential, clinical setting when it is being done for the good of science.

[gmonasco]

All the hair loss forums i'm a part of, i see at least 1/3 of those ppl get side effects from the drug. If it were the 2%, you'd rarely see a case of it.

That's not valid reasoning, because:

a) The sample is self-selecting. People are far more likely to post about experiencing side effects than they are to post that they aren't experiencing any side effects.

b) Sexual dysfunction (the most commonly reported side effect) has a huge psychological/psychosomatic aspect to it, so one cannot validly assume that propecia users who report experiencing it are actually being physically affected by the drug in that regard.