02-21-2016, 05:13 PM
can someone explain this to me in detail please, it would be much appreciated
02-21-2016, 05:33 PM
Not in detail, but a quick thought:
If cox inhibitors would work in any significant way, people would have realized by now. People with a history of heart attack (a LOT of plus 50 old men) are on a constant dose of aspirin for the rest of their lives. Asprin is a cox-1 and cox-2 inhibitor.
Also you wouldn´t want to mess with cox inhibitors, because cox-1 inhibitors cause ulcers (and if you combine them with pantoprazol etc. you will get the side effects of pantoprazol) and pure cox-2 inhibitors are associated with a higher risk of heart attacks and strokes (although it is debated).