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JulioGP
07-08-2015, 11:27 AM
Japanese cosmetic company Shiseido expects to have baldness cure on the market by 2018.

Three more years…

For much of my life I’ve been waiting for this moment. Even throughout my youth I glanced at the hairlines of relatives and wondered what would become of me. At the same time I figured medical science would have to have developed something by the time my hair would start falling out.

However, as I entered my thirties and began to look more and more like an octopus was attacking me when my hair got wet, there still seemed to be no true cure for baldness on the horizon. They were out there cloning sheep and growing ears on the backs of mice, but they still couldn’t give me a little action up top.

And just as I raised my razor to go the Bruce Willis route, a ray of hope shone on my news feed. It said that the cure to baldness actually lies inside me and my delicious stem cells, and that the key to unlocking it would be available in just three more years…


This isn’t some chemical treatment with only a chance of working and slew of side-effects. Nor is this some implant or transplant requiring you to take a leap of faith in your doctor’s artistic sensibilities. It’s a method to kickstart your own hair roots to work like they used to back when people were making money with rock music.

First medical staff will take some cells to reprogram as induced pluripotent stem cells, the scientific breakthrough that won Shinya Yamanaka the Nobel Prize and a fancy new washing machine back in 2012. At the moment it seems fibroblasts are the go-to ones for the job. These can be found in joints and scar tissue. That sounds a wee bit painful but there is already research into alternative methods such as getting them from urine.

Complete here:
http://en.rocketnews24.com/2015/07/08/japanese-cosmetic-company-shiseido-expects-to-have-baldness-cure-on-the-market-by-2018/

rdawg
07-08-2015, 11:30 AM
This is replicel, and let's not get ahead of ourselves, this is a very unproven treatment.

is it possible it works, 100%, but nothing has been proven here.

exciting to watch but don't go too crazy here.

I will admit the treatments have risen alot in the past year or two, alot of treatments starting or coming to the end of their phase II trials(BIM, CB, SM, SETI, Replicel)

JayM
07-08-2015, 11:41 AM
Really?! Have I just read the title of this post and the first line is sheishedo?

Please you have over 200 posts have you not visited the cutting edge section?

Not giving up
07-08-2015, 12:39 PM
i know no one has any real idea, but how much would something like this cost? A painful amount I imagine?

JayM
07-08-2015, 12:44 PM
Maybe but maybe not. And it's all relative really. If it's below 30k which it might be and means you don't lose more and they have improved on there previous results then I would pay it.

Not giving up
07-08-2015, 12:49 PM
I hope you're talking 30k as in US dollars and not British pound!

But yeah, if it provided a teenage hairline and head of hair for life I'd endure and pay that.

Trouse5858
07-08-2015, 12:58 PM
30 thousand dollars? Jesus Christ I'm only 24 there's no way I'd be able to afford that. Guess I'll start robbing banks if it means I can look like Patrick Sharp though...:D

It's2014ComeOnAlready
07-08-2015, 01:03 PM
30 thousand dollars? Jesus Christ I'm only 24 there's no way I'd be able to afford that. Guess I'll start robbing banks if it means I can look like Patrick Sharp though...:D

If it's $30,000, I'd gladly try and get a loan. If it means I don't ever have to worry about hair, or fin again? That is a bargain imo.

Illusion
07-08-2015, 01:07 PM
If it's $30,000, I'd gladly try and get a loan. If it means I don't ever have to worry about hair, or fin again? That is a bargain imo.

Exactly. The peace of mind a cure is going to give you is priceless. Goodbye BDD!

Not giving up
07-08-2015, 01:09 PM
30 thousand dollars is only 15 thousand British pounds (ish) so look at it that way and you've already halved the cost (optimistic logic) :p

Bald Russian
07-08-2015, 01:15 PM
http://en.rocketnews24.com/ - is this site creditable?
Tried to find any other source - nothing.
Many times discussed that new law, allows shisheido (if they started phase 2 this spring) to come into market during phase 2.
Just going from replicell pipeline - they claim that phase 2 will be crossed for one year, and i belive japaneses will make it faster, because japaneses always have ambitions to be first in the world. Even take a worse scenario - japaneses will take 2 years for phase 2. Why author of article wrote that it will be in 2018 and not 2017 for example?
I wish a cure come as soon as possible. Already saving money to be in first lines. Anybody has some contacts with Shisheido to spill the light on this question about their pipeline? Do they have any dedicated page for curing baldness?
Also interesting question - everybody knows that such radical solution is mostly for hard Norwoods, light norwoods like 2-3.5 can use some drugs to save hair. But what gonna do those light norwoods when a cure will come? They have too much hairs for paying a tons of money to cover a small bald spots and in same time they know that sooner or later they will become bald even with drugs (or simply tired of regimen). Are light norwoods will trying to find a way for fast losing hairs with future seeding hair cells? In this situation Norwood 6 looks much more profitably, because he lost his weak hairs and is ready to get full head of hair that resisting to baldness...

Paul73
07-08-2015, 01:29 PM
Really?! Have I just read the title of this post and the first line is sheishedo?

Please you have over 200 posts have you not visited the cutting edge section?

What´s the problem with his post? Maybe Replicel really has something for 2018.

macbeth81
07-08-2015, 01:37 PM
This was posted yesterday. As Rdawg pointed out, this is Replicel's technology, although never stated in the article. Unless Replicel/Sheishedo have drastically improved results, this will be no were near a cure. I wouldn't be surprised if 2018 is delayed unless they start trials soon. Anyway, Japan is late. Wasn't Aderans suppose to be released this year?

Sogeking
07-08-2015, 01:38 PM
What´s the problem with his post? Maybe Replicel really has something for 2018.

They are aiming for stopping hairloss but their treatment will be low on regrowth.

hellouser
07-08-2015, 01:41 PM
If it's $30,000, I'd gladly try and get a loan. If it means I don't ever have to worry about hair, or fin again? That is a bargain imo.

It'd be the best 30,000 dollars I'd spend.... ever. Talk about improving the quality of your life. Priceless.

JayM
07-08-2015, 01:46 PM
Haha I did mean British pounds but I just rolled a figure out there as we just don't know. Sheishedo has a massive set up in Japan and has all the networking ect so who knows. I only rolled 30k cuz after that money your not gonna have much donor left.

Paul73. There is a thread which is like millions of pages long about replicel on this forum. You throw a title like that out and I would expect something more than a company which published some of its first ideas about its treatments in like 2003. I'm not arguing replicel has something, I think they do but this isn't IFLS why say 'cure in 2018!' why not post this link in the replicel threads?

Newbies will click on this and be swayed by buzz words when really they could visit a thread with replicels mediocre results, delayed timelines and revised new timelines.

JulioGP
07-08-2015, 03:14 PM
Isn't a Replicel research. Both companys made a deal and now get together.

For me, there is no sense about the value that you sad, about 30k dollars, because is too expensive. I think that we need more time and all those informations about the price are speculations.

2018 is coming, not an impossible date.

JayM
07-08-2015, 03:27 PM
Wha? Replicel and sheishedo entered into a partnership and because of the regulations in Japan it could be on the Japanese market by 2018. It's the same technology replicel always had. Hopefully the delays mean they have improved the medicore results they had and to be fair they said they have improved the technology. It's all on the replicel/sheishedo thread as mentioned before.

30k was mentioned as a marker for what would be reasonable to pay in terms of getting a nw1. This is because currently if you exhaust the donor area, with a surgeon in the u.k it could cost this amount, maybe more.

You have over 200 posts why have you not read this? They are partners. Replicel have also stated when this passes stage 3 in America, they will look for another partner like sheishedo who specialise in delivering this treatment. Again noted in the other thread.

rdawg
07-08-2015, 03:50 PM
Wha? Replicel and sheishedo entered into a partnership and because of the regulations in Japan it could be on the Japanese market by 2018. It's the same technology replicel always had. Hopefully the delays mean they have improved the medicore results they had and to be fair they said they have improved the technology. It's all on the replicel/sheishedo thread as mentioned before.



that was just the POC results and it showed it definitely did something. They've definitely changed it a bit since then as that was like two years ago and they are just starting phase II now, does anyone have those results handy, i dont recall if they were 6 months after treatment or 12.

either way they definitely impressed sheishedo behind the scenes because you dont get a backer like that without showing proof of results to some extent, look at histogen, they had decent results and couldn't get any funding.

we'll see soon, Replicel is a bit behind some other treatments but there's no reason to scoff at it yet.

JayM
07-08-2015, 04:00 PM
Julio, apologies if my tone came across as rude mate I just felt like this belonged in the replicel/sheishedo thread and without the buzz words of cure ect. To be fair in this article they do keep mentioning IPS cells which is different to the original treatment? But I think someone mentioned it was probably a mistranslation. I think in the latest presentation they gave out last month was the same technique so it most likely is.

To be fair for me its the resistance to androgens which makes me the most excited. If they can do that to the majority of my follicles then great and solve the rest with a HT. 10,000 on the hairline please haha. And if it does that with amazing regrowth then there wont be a HT industry anymore.

JulioGP
07-08-2015, 04:47 PM
Take it Easy My friend, no problem.

Sometimes I do not have time to read all the forum threads, as a matter of extreme interest to all, I decided to share this information. I had not found the subjects in the generic posts. Anyway, I hope this scientific breakthrough actually reach the market soon. We are all anxious.

baldybald
07-08-2015, 08:57 PM
http://youtu.be/oKRwlNuDMU0

http://youtu.be/-p0Hvrx093I

Very interesting!

By the way the videos were taken from hair loss cure website.

Betoce
07-08-2015, 09:34 PM
Hi everyone,
everytime I see this video from Shiseido, i have a issue to understand, what they are saying when: "hereditary baldness cant use our technology".. After all, Male pattern baldness is an androgenetic alopecia... hereditary baldness.

luiza
07-09-2015, 03:31 AM
These news are spreading worldwide. I am from Brazil (although now I live in Australia) and everybody there thinks the cure for baldness was found because Shiseido news.

I sent Replicel an email around 2 months ago (they will actually reply if you send it) and asked about regrowth. They said that the method is focused on stoping further hair loss and not giving regrowth. However they claim their technology is also able to form NEW follicles, aside from waking up the dormant ones we already have. So I wonder if increasing the number of injections won't lead to a full head of hair. I know it would be pricey but as you are saying, if it would give me back all hair I had before, I would gladly pay for that.

For example, if we got only 15% of regrowth with this, maybe we would just need around 7 injections to form new follicles and get 100% satisfaction? (I'm not saying it will be possible and I'm excluding the possibility of it being dangerous, I'm just wondering)

Being a 22 years old girl losing her hair since the age of 14, it is hard not to be both anxious and excited about it.

What do you guys think?

Arieux
07-09-2015, 03:49 AM
However they claim their technology is also able to form NEW follicles, aside from waking up the dormant ones we already have.


They confirmed it also on their facebook fanpage yesterday:


will the cure for hairloss work for only awakening the dormant follicles or also to create new follicles ? I mean what for those people which have no follicles left ?


Thank you for your question. Our animal models showed both happening and we have designed our phase 2 trial to include biopsies from some of the subjects so we can look beneath the skin to analyze how the cells react to dormant hair follicles and if new follicles are created. We anticipate starting our phase 2 trial before the end of this year.

And when it comes to price, there was a long discussion on *** about it based on one interview from 2014: http://video.foxbusiness.com/v/3775771951001/new-fix-for-tendon-injuries/?#sp=show-clips
About minute 3, he claimed, that estimated cost of the treatment inluding cell cultivation will be around 3-5k dollars. But this price refers to their treatment of tendon injuries, nevertheless it is good orientation point. They have never showed the price for treating baldness, because it will be dependent on the doses. And dosing problem will be analysed exactly in their phase starting this year.

luiza
07-09-2015, 04:21 AM
That's good, Arieux! Is it in Replicel's or Shiseido's page?!
I want to believe it is the cure but at the same time I am afraid of having high hopes and then getting disappointed :(



And when it comes to price, there was a long discussion on *** about it based on one interview from 2014: http://video.foxbusiness.com/v/3775771951001/new-fix-for-tendon-injuries/?#sp=show-clips
About minute 3, he claimed, that estimated cost of the treatment inluding cell cultivation will be around 3-5k dollars. But this price refers to their treatment of tendon injuries, nevertheless it is good orientation point. They have never showed the price for treating baldness, because it will be dependent on the doses. And dosing problem will be analysed exactly in their phase starting this year.

If it will be around $5k per treatment and I would get more and more hair with every treatment, I would definitely pay for 5 sessions or even more hahah I just want my hair back :(

TooMuchHairWontKillYou
07-09-2015, 04:51 AM
That's good, Arieux! Is it in Replicel's or Shiseido's page?!
I want to believe it is the cure but at the same time I am afraid of having high hopes and then getting disappointed :(




If it will be around $5k per treatment and I would get more and more hair with every treatment, I would definitely pay for 5 sessions or even more hahah I just want my hair back :(

i dont want to dissappoint you but i dont think that if 1 treatment gives you 15% regrowth then 2 treatments will give you 30%

if it works like that i will apply a lot of minox and will get all of my hair back :d

lacazette
07-09-2015, 05:23 AM
Hey Luiza, we really know how it hurts to loose our hair, and it's even more difficult for a young woman like you but there's hope for the future! ;)

Sisheido sounds promising, especially if they ameliore the replicel process in those clinical trials ( I saw on an article that their researchers have big knowledge in hair loss and could add their competence to enhance the product)(that's why maybe we heard about iPS cell now unlike before)
But don't put all your hopes on them, luckily there's other treatments that are in phase2/3 and sounds promising also for the near future (wnt pathway drug, setipiprant drug, stem cells therapies). Treatments that will help us to stop hair loss, and hopefully with good regrowth. I'll tell you more about them when I have time, but if you search here or on internet you will find info on them

And those treamtments will help us to wait until the real cure like 'follicular neogenesis' treament. that thing will create complete new functional follicles for us. that will take longer in time but it will be the end of our problem ( US army begin soon clinical trial for Bioprinted skin graft ( a complete new skin, with new glands and new hair follicles that are working normally. They say in their patents that it will work for burned skin but also for hair loss), there's also few companies that are working on follicle neogenesis for hairloss
There's also the '3D cell culture' thing, researchers have succcesfully grow a new hair follicle with replicating dermal papilla cells,etc.. (Sandford and burnam researchers ) they said they think they could go in clinical trial in two years from now ( to perfect their method, and see the cancer safety before they tried on humans)
Those things will be the 'real cure', but maybe things like sisheido, histogen, samumed, etc that will come sooner , these treatments alone or in combination with good HT or even smp will work enough for us to have a decent haircut and live a normal life without being anxious everyday about our hair.

So it's promising for future but for the moment we have nothing of them lol Do you check your hormones level? your thyroid? your vitamins,zinc? do you take any treatment? Does your hair loss is aggressive, you already see your scalp? maybe with some research you could find a factor that accelerate your hair loss, and if you find it you could slow the process of hair loss. It could help you to wait until new treatments

good luck sista hehe we feel your pain ;)

luiza
07-09-2015, 07:15 AM
i dont want to dissappoint you but i dont think that if 1 treatment gives you 15% regrowth then 2 treatments will give you 30%

if it works like that i will apply a lot of minox and will get all of my hair back :d

Well, minox will never create new follicles but I reckon you are right, it won't be like that, that's just me trying to be optimistic lol

luiza
07-09-2015, 07:35 AM
Hey Luiza, we really know how it hurts to loose our hair, and it's even more difficult for a young woman like you but there's hope for the future! ;)

Sisheido sounds promising, especially if they ameliore the replicel process in those clinical trials ( I saw on an article that their researchers have big knowledge in hair loss and could add their competence to enhance the product)(that's why maybe we heard about iPS cell now unlike before)
But don't put all your hopes on them, luckily there's other treatments that are in phase2/3 and sounds promising also for the near future (wnt pathway drug, setipiprant drug, stem cells therapies). Treatments that will help us to stop hair loss, and hopefully with good regrowth. I'll tell you more about them when I have time, but if you search here or on internet you will find info on them

Thank you for your answer ;) it is really such a nightmare for us to live like that (even though I don't think the shaved look looks bad on most of the man :P but I definitely don't have this option haha)



And those treamtments will help us to wait until the real cure like 'follicular neogenesis' treament. that thing will create complete new functional follicles for us. that will take longer in time but it will be the end of our problem ( US army begin soon clinical trial for Bioprinted skin graft ( a complete new skin, with new glands and new hair follicles that are working normally. They say in their patents that it will work for burned skin but also for hair loss), there's also few companies that are working on follicle neogenesis for hairloss
There's also the '3D cell culture' thing, researchers have succcesfully grow a new hair follicle with replicating dermal papilla cells,etc.. (Sandford and burnam researchers ) they said they think they could go in clinical trial in two years from now ( to perfect their method, and see the cancer safety before they tried on humans)
Those things will be the 'real cure', but maybe things like sisheido, histogen, samumed, etc that will come sooner , these treatments alone or in combination with good HT or even smp will work enough for us to have a decent haircut and live a normal life without being anxious everyday about our hair.

I believe hair multiplication is what we will first call a cure cause it will give hair even for people with issues like scar tissue. However every single forum I go I see people saying that this is all bullshit and the cure will always be 10 years aways. That actually makes me sad cause I've been throwing all my youth away because of my hair and it seems that it never changes :(
Are they actually going to do trials? I had lots of hope in Dr Lauster and his team but I never find any news about them and it seems they only test it in mice, tell us it works and then stop researching lol It really hurts me :(
I was thinking about just shaving my head and getting a hair system but my hair now is not THAT bad to go into that route, so I'm thinking maybe I should wait for these new treatments to come. But what I really want is a cure, obviously.



So it's promising for future but for the moment we have nothing of them lol Do you check your hormones level? your thyroid? your vitamins,zinc? do you take any treatment? Does your hair loss is aggressive, you already see your scalp? maybe with some research you could find a factor that accelerate your hair loss, and if you find it you could slow the process of hair loss. It could help you to wait until new treatments

good luck sista hehe we feel your pain ;)

My hair loss is the female pattern one but it was definitely triggered by stress. I was only 14 when it started and I was going through a lot. At that time I lost around 60% of my hair. With a lot of treatments (such as vitamins, minoxidil, hormones, etc) I got around 30% back, so I still miss 30% of my hair haha it doesn't look so bad (except for the crown) and I can hide it but it is a hassle having to hide it everyday and not being able to style it (cause there's not enough hair).

Well, good luck for all of us :) thank you!!

FooFighter
07-09-2015, 07:37 AM
Hey Luiza, we really know how it hurts to loose our hair, and it's even more difficult for a young woman like you but there's hope for the future! ;)

Sisheido sounds promising, especially if they ameliore the replicel process in those clinical trials ( I saw on an article that their researchers have big knowledge in hair loss and could add their competence to enhance the product)(that's why maybe we heard about iPS cell now unlike before)
But don't put all your hopes on them, luckily there's other treatments that are in phase2/3 and sounds promising also for the near future (wnt pathway drug, setipiprant drug, stem cells therapies). Treatments that will help us to stop hair loss, and hopefully with good regrowth. I'll tell you more about them when I have time, but if you search here or on internet you will find info on them

And those treamtments will help us to wait until the real cure like 'follicular neogenesis' treament. that thing will create complete new functional follicles for us. that will take longer in time but it will be the end of our problem ( US army begin soon clinical trial for Bioprinted skin graft ( a complete new skin, with new glands and new hair follicles that are working normally. They say in their patents that it will work for burned skin but also for hair loss), there's also few companies that are working on follicle neogenesis for hairloss
There's also the '3D cell culture' thing, researchers have succcesfully grow a new hair follicle with replicating dermal papilla cells,etc.. (Sandford and burnam researchers ) they said they think they could go in clinical trial in two years from now ( to perfect their method, and see the cancer safety before they tried on humans)
Those things will be the 'real cure', but maybe things like sisheido, histogen, samumed, etc that will come sooner , these treatments alone or in combination with good HT or even smp will work enough for us to have a decent haircut and live a normal life without being anxious everyday about our hair.

So it's promising for future but for the moment we have nothing of them lol Do you check your hormones level? your thyroid? your vitamins,zinc? do you take any treatment? Does your hair loss is aggressive, you already see your scalp? maybe with some research you could find a factor that accelerate your hair loss, and if you find it you could slow the process of hair loss. It could help you to wait until new treatments

good luck sista hehe we feel your pain ;)

Stem cells are still at an early stage of development unfortunately. It will need probably another 20-30 years to get quality therapies. They have amazing potential, but still many things we do not know about them. It is a long way to bring sucessful and safe therapy to the market and it is not so easy like we think. Around 90% of stem cell research is done on mouse, because they have potential to be cancer tumors if we don’t know how to control them.


The best source of stem cells (embryonic stem cell) are still part of a lot controversy and limited research.

luiza
07-09-2015, 08:11 AM
If it takes 30 years I'll be 52 when it comes out haha not good news :( I wont even care this much about hair (or maybe I wll)

luiza
07-09-2015, 08:13 AM
I know it might sound crazy but what about Biofibre implants? I KNOW it was banned in USA in the past and it is considered dangerous, so no one even thinks about it, but I mean, what about in the future?
If they can do fake breast implants, fake teeth implants and all other stuff, why not hair? I mean, it could be improved.
I know hair is something more complex cause we can't have the same hairs forever and they have to shed and regenerate but if they could do something that sheds like our own hair over time and just needs to be maintained, maybe it would work?
I don't mean I would do it now but lately they are using reversible knots and it is said to cause rejection in less than 2% of users. It is getting famous in Italy and Japan, so maybe they will improve this technology.

I obviously want something that us actually mine and will grow and regenerate but I can't wait for 20 or 30 years and I think we might have other options soon and no one is considering them now.

Again, guys, I'm not saying it is safe, I'm saying it COULD be safer in the future. :)

Hemo
07-09-2015, 08:20 AM
The quote from their facebook page basically confirms the "cure" talk is total BS and up in the air...they admit they still don't know how dormant follicles will react, which to me is the main factor when discussing a true cure.

lacazette
07-09-2015, 08:53 AM
[QUOTE=FooFighter;211988]Stem cells are still at an early stage of development unfortunately. It will need probably another 20-30 years to get quality therapies. They have amazing potential, but still many things we do not know about them. It is a long way to bring sucessful and safe therapy to the market and it is not so easy like we think. Around 90% of stem cell research is done on mouse, because they have potential to be cancer tumors if we don’t know how to control them.

I think you're too much pessimistic dude . Stem cells progress in an exponential way, and at a speed level incredibly higher than those last 20 years. Researchers already overcomed the controversy issue, as they don't need embryonic cells anymore. They needed them for duplicate them in any precise cell they want. But now it's our own cells that they're using (and found how to duplicate them in the type of cell they want) so no more controversy problem
and look all the progress on recent published studies , you'll be suprise. Some of them find a way of purification of cells that lead to quasi no cancer risks, others found a method to do all that cell culture 100 times cheaper than actual methods, and many things like that if you search.

I could be right with you for the "real cure" in 20 years, but not for safe stem cell therapies. they are already in advanced clinical trials, without side effects for the moment, like histogen, shisheido. And if you look their approval timeline in japan : http://www.google.fr/imgres?imgurl=http%3A%2F%2Fjbpress.ismedia.jp%2Fmw imgs%2F6%2Fa%2F650%2Fimg_6a6d2c2f88a38ea25fbc42e67 2d4e703188672.jpg&imgrefurl=http%3A%2F%2Fjbpress.ismedia.jp%2Farticl es%2F-%2F39710&h=500&w=650&tbnid=auOKEqCM2qWb2M%3A&zoom=1&docid=DEIJWsrMVzuZ7M&ei=5xqLVaatC8rSU7-qkZgJ&tbm=isch&iact=rc&uact=3&dur=254&page=1&start=0&ndsp=16&ved=0CCEQrQMwAA

bro it changes a lot in term of timeline. they just have to prove safety, and could have an approval even before the end of phase 2!
So let's prepare travelling, cause if something comes out, it will arrive in europe/usa for mainstream use 5/10 years after japan for sure ( unless Cures century bill change the fda regard on regenerative medecine)

With that dude you can't be over pessimistis and think it will be like these last 20 years we lived before, you also add the things like for exemple

the Wnt pathway world,really promising, with a product that is finishing his phase 2, or

the US army that begin clinical trial for bioprinted skin grafts ( with new functional hair follicles), bioprinteed organs that is in terrific progress
"New advancements create opportunities for everything from 3D printable skin, stem cells and other minute medical applications. According to IDTechEx analysts, the 3D printing medical market is expected to expand by 365% to $867m by 2025. With the advancement of bioprinting, the medical market could reach up to $6bn in 10 years. Now this is an industry to invest time in.

bim,seti, and other drugs,pilloscopy that could lead with no scar and better yield HT,etc..

well we don't need THE real cure, if just one comes out with good results, in combination with actual treatments, I'm sure we could have not the john Travolta hair cut haha but at least a decent one,and to wait more peacefully 10 or 20 more years for the end of this nightmare :)

I like that phrase héhé :
bill gates "We always overestimate the change that will occur in the next two years and underestimate the change that will occur in the next ten."

Trenblastoise
07-09-2015, 10:10 AM
I see this coming up here and there.
"Its so bad to lose hair.." I agree. "...especially if you are a girl/woman"
I don't really agree there, they might be more affected by it emotionally, tho I don't really think so given we have several users who has been here showing serious depression.

But my point is simply, the women I have come across who has lost their hair or in the progress of it still easily acquire physical intimacy. Take a short balding guy for instance, they usually struggle hard with getting women. I just haven't come across any woman who has had it difficult finding a sexual or intimate partner, it seems to me a lot of their problems are just in their head.

I don't wish to discredit that they feel bad, obviously it is a big loss, as it is for men, but I just haven't been presented with the rational reasoning of why it is so much worse for women. Even if you got hair as a male you will often have to put up lots of resources to get with a women, they simply swipe yes/no with no need to hold up an interesting conversation. Least in my country and based on my experience anyway. Maybe it is different out there, maybe in your countries it is the women who must gather their courage and start chatting with the men with the risk of rejection if she isn't funny or pretty enough, then certainly hair loss on top off it would be a big blow as you are competing with the other women.

Again I don't wish to take away any of the suffering women go through, or men. I just haven't heard the reasoning why and it would be interesting if someone here could point it out or their opinion of it I don't mean to offend:) Maybe someone can enlighten me or give me some further insight.

luiza
07-09-2015, 10:25 AM
I see this coming up here and there.
"Its so bad to lose hair.." I agree. "...especially if you are a girl/woman"
I don't really agree there, they might be more affected by it emotionally, tho I don't really think so given we have several users who has been here showing serious depression.

But my point is simply, the women I have come across who has lost their hair or in the progress of it still easily acquire physical intimacy. Take a short balding guy for instance, they usually struggle hard with getting women. I just haven't come across any woman who has had it difficult finding a sexual or intimate partner, it seems to me a lot of their problems are just in their head.

I don't wish to discredit that they feel bad, obviously it is a big loss, as it is for men, but I just haven't been presented with the rational reasoning of why it is so much worse for women. Even if you got hair as a male you will often have to put up lots of resources to get with a women, they simply swipe yes/no with no need to hold up an interesting conversation. Least in my country and based on my experience anyway. Maybe it is different out there, maybe in your countries it is the women who must gather their courage and start chatting with the men with the risk of rejection if she isn't funny or pretty enough, then certainly hair loss on top off it would be a big blow as you are competing with the other women.

Again I don't wish to take away any of the suffering women go through, or men. I just haven't heard the reasoning why and it would be interesting if someone here could point it out or their opinion of it I don't mean to offend:) Maybe someone can enlighten me or give me some further insight.

Hair loss is definitely more acceptable for men. I know people make jokes when you are already balding in your early twenties and I know it also affects you. But women are seen as sick when they lose their hair. It is much more rare for us and we have less options than you. We can't take finasteride, we can't just don't give a **** and shave it off. It is sociable not acceptable.
I have always had long hair (I still do) and used to do many styles with it. And now I just can't do anything cause it looks crap.
I'm not a short hair person and my mum keeps telling me I should get a short haircut. It bothers me a lot.

When men are seen with thinning hair people usually make jokes. When it comes to women people ask you what's going on. I was asked once if I was treating for cancer. Trust me, it is awful. I'm not saying you guys should do it and I know it must be hard but if I was a man and had the option of getting my head shaved, I would have done it years ago cause it screws me up so badly I can't even explain.
And yes, I have developed depression and anxiety because of this. When it was worse than what is now I had my girl friends telling me I was really strong and they wouldn't know how to deal with it. Hair is one of the most important things for us. We love to be able to change it and style it. It is part of our identity and most of girls at my age like to keep it long.

Maybe you don't see many depressed female users cause as I said, it is more rare for women to get bald, even though it has been changing lately.

Also, for me it is not about how men see me. I still get a lot of attention from men and I have a really supportive boyfriend. The problem is how I see myself. If I don't know how to love myself and be confident, I don't know how someone else will.
If you are a bald guy and still have lots of confidence you will easily get girls, cause that's what we like in men, no matter how they look. Trust me. :)

Dench57
07-09-2015, 10:33 AM
Agree with the lady above. Hairloss is ****ing awful for all of us but it's much worse for women.

Trenblastoise
07-09-2015, 10:42 AM
Hair loss is definitely more acceptable for men. I know people make jokes when you are already balding in your early twenties and I know it also affects you. But women are seen as sick when they lose their hair. It is much more rare for us and we have less options than you. We can't take finasteride, we can't just don't give a **** and shave it off. It is sociable not acceptable.
I have always had long hair (I still do) and used to do many styles with it. And now I just can't do anything cause it looks crap.
I'm not a short hair person and my mum keeps telling me I should get a short haircut. It bothers me a lot.

When men are seen with thinning hair people usually make jokes. When it comes to women people ask you what's going on. I was asked once if I was treating for cancer. Trust me, it is awful. I'm not saying you guys should do it and I know it must be hard but if I was a man and had the option of getting my head shaved, I would have done it years ago cause it screws me up so badly I can't even explain.
And yes, I have developed depression and anxiety because of this. When it was worse than what is now I had my girl friends telling me I was really strong and they wouldn't know how to deal with it. Hair is one of the most important things for us. We love to be able to change it and style it. It is part of our identity and most of girls at my age like to keep it long.

Maybe you don't see many female depressed users cause as I said, it is more rare for women to get bald, even though it had been changing lately.

Sure, I agree it is more rare. On options I don't know. You claim you can't take finasteride but there was one here who did. Regardless taking you at face value, it's much more acceptable for women to wear wigs and hair systems. I have also encountered several women who have just shaved it off, and have seen several of them in the media hailed as gods.

I too can't do much with my hair, I have one style that's okay, and that's the way it is. Some men make jokes of their own hair loss, but often there is a lot of emotion behind it they put up a tough face to hide it. You can't be a whining man or you get no where, you need to be confident no matter what -- which women does not, plenty of women with no confidence have no problems getting mates because they are the ones swiping and not going up and risking their reputation.


You can't simply shave it and be fine, you need to have certain traits to look well with it, a good jaw, good head shape, good facial aesthetics, tall, tan and muscly. You don't need all:) Likewise it screws me up more than I can explain, I have zero contact with women anymore, it's no point, it's just rejections. And those who don't have insane standards and give little if anything back for me anyway, I know there are tons of men without hair and great success (But also seen bald women with great success). Anyway by all means I don't object to many of them going through depression and emotional pain - but what are the _actual_ consequences? Can you still get along with a man? Do you find yourself having to put lots and lots of resources and rejections to get with men or is it even "impossible"? I don't mean to offend you as I have already stated, I just want some insight in why it is supposedly "much worse" for women. I am thankful for your post, it explains some of the mindset I thought a woman could have!

It sucks to get asked if you are sick. I have on two occasions been made fun of in front of a group of people(First time was my ex, second time was my father), not an experience I would wish on anyone:)

I am sorry for your suffering hopefully we get something good here eventually. I suppose most here should prepare some money for it:)

luiza
07-09-2015, 11:15 AM
Sure, I agree it is more rare. On options I don't know. You claim you can't take finasteride but there was one here who did. Regardless taking you at face value, it's much more acceptable for women to wear wigs and hair systems. I have also encountered several women who have just shaved it off, and have seen several of them in the media hailed as gods.

I too can't do much with my hair, I have one style that's okay, and that's the way it is. Some men make jokes of their own hair loss, but often there is a lot of emotion behind it they put up a tough face to hide it. You can't be a whining man or you get no where, you need to be confident no matter what -- which women does not, plenty of women with no confidence have no problems getting mates because they are the ones swiping and not going up and risking their reputation.


You can't simply shave it and be fine, you need to have certain traits to look well with it, a good jaw, good head shape, good facial aesthetics, tall, tan and muscly. You don't need all:) Likewise it screws me up more than I can explain, I have zero contact with women anymore, it's no point, it's just rejections. And those who don't have insane standards and give little if anything back for me anyway, I know there are tons of men without hair and great success (But also seen bald women with great success). Anyway by all means I don't object to many of them going through depression and emotional pain - but what are the _actual_ consequences? Can you still get along with a man? Do you find yourself having to put lots and lots of resources and rejections to get with men or is it even "impossible"? I don't mean to offend you as I have already stated, I just want some insight in why it is supposedly "much worse" for women. I am thankful for your post, it explains some of the mindset I thought a woman could have!

It sucks to get asked if you are sick. I have on two occasions been made fun of in front of a group of people(First time was my ex, second time was my father), not an experience I would wish on anyone:)

I am sorry for your suffering hopefully we get something good here eventually. I suppose most here should prepare some money for it:)

First, I wouldn't see any problem if I met a man who wears a hair system (a wig would be weird though. I find it weird even for women). You guys say it is seen as ridiculous for a guy to use a piece but trust me, it is not. It just means you rather have hair and you don't like the shaved look.
I've seen many men saying they would lose their masculinity if they wore a hair system LOL
I think you guys kind of start losing your confidence and stop approaching women and then are not able anymore to realise the way we think. I can tell you 90% of girls won't mind if you wear hair. You guys are the ones who create a scenario in your minds where a girl will dump you when she finds out you are wearing a piece. If you wear hair and shows confidence as you weren't wearing anything, we will not mind.
I understand it's not just like "shave it off and done, solved!". I know a great body helps. But I am in good shape and it wouldn't help much having a good body but being bald when you are a girl hahah
I was thinking about wearing hair but I still have quite "a lot" of my bio hair to just jump into that route. It is so hard to decide when you are in the middle of the line :(

The girls who shave it off and are happy with it are usually girls that don't suffer from hair loss haha I wanted to shave my head once in life to feel how it is but not because I have to! That's the point, we feel abnormal and sick :( I've never seen a girl going through hair loss and accepting the idea of shaving.

Everyone has to be confident, no matter if they are woman or man. I can make boys come to me without moving a finger but I can't make them stay when I feel shit all the time. I'm having some problems with my boyfriend lately cause I'm always moody because of my hair and even though he doesn't see any problem he tells me I'm always pretty but much more when I'm confident. That's the whole point. :)

Sorry for my bad English :P

FooFighter
07-09-2015, 11:27 AM
[QUOTE=FooFighter;211988]Stem cells are still at an early stage of development unfortunately. It will need probably another 20-30 years to get quality therapies. They have amazing potential, but still many things we do not know about them. It is a long way to bring sucessful and safe therapy to the market and it is not so easy like we think. Around 90% of stem cell research is done on mouse, because they have potential to be cancer tumors if we don’t know how to control them.

I think you're too much pessimistic dude . Stem cells progress in an exponential way, and at a speed level incredibly higher than those last 20 years. Researchers already overcomed the controversy issue, as they don't need embryonic cells anymore. They needed them for duplicate them in any precise cell they want. But now it's our own cells that they're using (and found how to duplicate them in the type of cell they want) so no more controversy problem
and look all the progress on recent published studies , you'll be suprise. Some of them find a way of purification of cells that lead to quasi no cancer risks, others found a method to do all that cell culture 100 times cheaper than actual methods, and many things like that if you search.

I could be right with you for the "real cure" in 20 years, but not for safe stem cell therapies. they are already in advanced clinical trials, without side effects for the moment, like histogen, shisheido. And if you look their approval timeline in japan : http://www.google.fr/imgres?imgurl=http%3A%2F%2Fjbpress.ismedia.jp%2Fmw imgs%2F6%2Fa%2F650%2Fimg_6a6d2c2f88a38ea25fbc42e67 2d4e703188672.jpg&imgrefurl=http%3A%2F%2Fjbpress.ismedia.jp%2Farticl es%2F-%2F39710&h=500&w=650&tbnid=auOKEqCM2qWb2M%3A&zoom=1&docid=DEIJWsrMVzuZ7M&ei=5xqLVaatC8rSU7-qkZgJ&tbm=isch&iact=rc&uact=3&dur=254&page=1&start=0&ndsp=16&ved=0CCEQrQMwAA

bro it changes a lot in term of timeline. they just have to prove safety, and could have an approval even before the end of phase 2!
So let's prepare travelling, cause if something comes out, it will arrive in europe/usa for mainstream use 5/10 years after japan for sure ( unless Cures century bill change the fda regard on regenerative medecine)

With that dude you can't be over pessimistis and think it will be like these last 20 years we lived before, you also add the things like for exemple

the Wnt pathway world,really promising, with a product that is finishing his phase 2, or

the US army that begin clinical trial for bioprinted skin grafts ( with new functional hair follicles), bioprinteed organs that is in terrific progress
"New advancements create opportunities for everything from 3D printable skin, stem cells and other minute medical applications. According to IDTechEx analysts, the 3D printing medical market is expected to expand by 365% to $867m by 2025. With the advancement of bioprinting, the medical market could reach up to $6bn in 10 years. Now this is an industry to invest time in.

bim,seti, and other drugs,pilloscopy that could lead with no scar and better yield HT,etc..

well we don't need THE real cure, if just one comes out with good results, in combination with actual treatments, I'm sure we could have not the john Travolta hair cut haha but at least a decent one,and to wait more peacefully 10 or 20 more years for the end of this nightmare :)

I like that phrase héhé :
bill gates "We always overestimate the change that will occur in the next two years and underestimate the change that will occur in the next ten."

Yes, and all that have been done on mouse:)

We are still far away from practical use.

iPS stem cells are not that powerful like embryonic stem cells and 99% of stem cells die in body after 2-3 days.

Arieux
07-09-2015, 11:37 AM
As far as I know, besides of preclinical animal studies, replicel safety has been confirmed in phase 1 which was conducted on human subjects. And this technology will be available, according to japan law, after safe data from phase II (2018).

Joan
07-09-2015, 12:13 PM
I see this coming up here and there.
"Its so bad to lose hair.." I agree. "...especially if you are a girl/woman"
I don't really agree there, they might be more affected by it emotionally, tho I don't really think so given we have several users who has been here showing serious depression.

But my point is simply, the women I have come across who has lost their hair or in the progress of it still easily acquire physical intimacy. Take a short balding guy for instance, they usually struggle hard with getting women. I just haven't come across any woman who has had it difficult finding a sexual or intimate partner, it seems to me a lot of their problems are just in their head.

I don't wish to discredit that they feel bad, obviously it is a big loss, as it is for men, but I just haven't been presented with the rational reasoning of why it is so much worse for women. Even if you got hair as a male you will often have to put up lots of resources to get with a women, they simply swipe yes/no with no need to hold up an interesting conversation. Least in my country and based on my experience anyway. Maybe it is different out there, maybe in your countries it is the women who must gather their courage and start chatting with the men with the risk of rejection if she isn't funny or pretty enough, then certainly hair loss on top off it would be a big blow as you are competing with the other women.

Again I don't wish to take away any of the suffering women go through, or men. I just haven't heard the reasoning why and it would be interesting if someone here could point it out or their opinion of it I don't mean to offend:) Maybe someone can enlighten me or give me some further insight.

I'm 52 and feel that it's worse for ANYONE, male or female, who is young (teens, 20s) to lose hair. Luiza, you and I are both not at the point of needing to wear hair, so we truly do not know how we are going to feel when (if) we get there. If it were common to see women with shaved/bald heads, I don't think it would be as easy as you think to just shave it off. We, like men, would need good facial aesthetics to pull it off. I, for one, do not have that and would NEVER, EVER walk around bald in public. Plus, we have the advantage of wearing makeup to detract from facial flaws, whereas men do not. My son is 20 and losing hair fast. It's going to be tough for him to pull off the bald look. I feel way worse for him than I do for myself. I, too, feel far worse for all those who are having their youth robbed from them due to this disease. I had mine with a full head of hair, and I wish to God everyone I read about on these forums did too.

GSD
07-09-2015, 12:26 PM
women still have make up.....

balding since 16.. and yes it sucks when people think that ur 10 years older :/

FooFighter
07-09-2015, 12:54 PM
women still have make up.....

balding since 16.. and yes it sucks when people think that ur 10 years older :/

People on forums must stop acting like b*tches, because there are much worst diseases. Lets go and ask people how they live with heart failure, stroke, cancer, paralyzed, blind, autism and other very painful diseases. I will be much more happy if i see cure for these kind of diseases than MPB. Yes, its nice to have full head with hair, but that is not my priority in life.

TooMuchHairWontKillYou
07-09-2015, 01:03 PM
People on forums must stop acting like b*tches, because there are much worst diseases. Lets go and ask people how they live with heart failure, stroke, cancer, paralyzed, blind, autism and other very painful diseases. I will be much more happy if i see cure for these kind of diseases than MPB. Yes, its nice to have full head with hair, but that is not my priority in life.

daaat logic :facepalm

bigentries
07-09-2015, 01:37 PM
First, I wouldn't see any problem if I met a man who wears a hair system (a wig would be weird though. I find it weird even for women)

"Hair system" is a fancy name for a wig.

You are delusional if you think 90% of women wouldn't care about a hair system. The social stigma is brutal for men wearing systems.

Hell, I recently met someone that was outed as a user and I can tell you he became a walking joke for the women that know him

This forum is more into new treatments. There are others where people mostly go to vent, and believe me, some guys have been dumped because of their hair loss

Illusion
07-09-2015, 02:05 PM
I'm 52 and feel that it's worse for ANYONE, male or female, who is young (teens, 20s) to lose hair. Luiza, you and I are both not at the point of needing to wear hair, so we truly do not know how we are going to feel when (if) we get there. If it were common to see women with shaved/bald heads, I don't think it would be as easy as you think to just shave it off. We, like men, would need good facial aesthetics to pull it off. I, for one, do not have that and would NEVER, EVER walk around bald in public. Plus, we have the advantage of wearing makeup to detract from facial flaws, whereas men do not. My son is 20 and losing hair fast. It's going to be tough for him to pull off the bald look. I feel way worse for him than I do for myself. I, too, feel far worse for all those who are having their youth robbed from them due to this disease. I had mine with a full head of hair, and I wish to God everyone I read about on these forums did too.

Yeah, it kinda sucks when you're 17 and are already forced to go on dutasteride just for maintaining the hair you have right now.

It's funny because when I see people in their late 20's (or older) coming to this forum and b!tching about them having receded to a NW2, I really have very little respect for them. They've had their youth with a good head of hair, they don't know really know how devastating hair loss can be.

macbeth81
07-09-2015, 02:11 PM
As far as I know, besides of preclinical animal studies, replicel safety has been confirmed in phase 1 which was conducted on human subjects. And this technology will be available, according to japan law, after safe data from phase II (2018).

To expand, Replicel extended Phase I/IIa trials and will take final safety measures in 2016. This will provided data over 60 months (5 years). Although the sample size is small (19), it should give some idea regarding safety.


Regarding the side topic, I saw a photograph posted a week ago on another forum of a woman without limps. She was young and had an otherwise great body. The males responding said they would "bang that". So if a woman without limbs can get affection, do young women without hair really have it harder?

Another point is that society is sympathetic toward women suffering, especially younger, otherwise pretty women. There was an article on CNN this week regarding a cave collapse in Washington. The article mentioned that the age and sex of the dead was unknown. Yes, it matters that much. Today headlines read "Body of Woman, 34, Killed in Washington Ice Cave Collapse ..." and "34-year-old woman's body recovered from ice cave collapse". Enough said.

JayM
07-09-2015, 02:20 PM
It's great to hear that they are getting those trialists back in and I think this what the comment on there facebook page meant by them taking biopsies. But I mean if they walk in with the same/Better amount of hair before the treatment after 5 years then it will certainly be uplifting.

macbeth81
07-09-2015, 02:28 PM
Sorry, I don't know if they are checking hair growth after 5 years. Their trial is registered on clinicaltrials.gov and it doesn't mention analyzing hair growth at 60 months, only safety data.

https://clinicaltrials.gov/ct2/show/NCT01286649?term=trichoscience&rank=1

Trouse5858
07-09-2015, 02:39 PM
Regarding the side topic, I saw a photograph posted a week ago on another forum of a woman without limps. She was young and had an otherwise great body. The males responding said they would "bang that".

This has my mind in a goddamn pretzel. How the f*ck does one have a 'nice' body sans arms and legs or are you just being totally facetious?

macbeth81
07-09-2015, 03:06 PM
This has my mind in a goddamn pretzel. How the f*ck does one have a 'nice' body sans arms and legs or are you just being totally facetious?

Otherwise nice body.

Search "She doesn't look half bad - GIF on Imgur" you can find the same photograph (in bikini, no nudity).

NeedHairASAP
07-09-2015, 03:58 PM
"Hair system" is a fancy name for a wig.

You are delusional if you think 90% of women wouldn't care about a hair system. The social stigma is brutal for men wearing systems.

Hell, I recently met someone that was outed as a user and I can tell you he became a walking joke for the women that know him

This forum is more into new treatments. There are others where people mostly go to vent, and believe me, some guys have been dumped because of their hair loss

They didn't get dumped because of their hair loss

They got dumped because they are literally unrecognizable after hair loss... i.e. ugly

It's not the process, it's the result.

If your gf gained 100 pounds and looked legit unrecognizable and uncomparable to her former self-- you'd most likely dump her.

The painful thing is, you're fat girlfriend could have cut back on the cupcakes, whereas you are genetically programmed to look like a walking corpse and there is nothing you can do about it

JayM
07-09-2015, 05:11 PM
Sorry, I don't know if they are checking hair growth after 5 years. Their trial is registered on clinicaltrials.gov and it doesn't mention analyzing hair growth at 60 months, only safety data.

https://clinicaltrials.gov/ct2/show/NCT01286649?term=trichoscience&rank=1

It would Deffo be stupid not to though. And you would visually be able to see if someone has balded after 5 years.

JulioGP
07-10-2015, 02:32 AM
Indeed this news cheered the whole world. I want to believe that when they say the word "cure," they refer to something that has already been caused and can be reversed. Some mentioned that in fact this treatment would be to prevent Baldness, which I do not. If it was that they did not announce as a cure but as "definitive prevention." Anyway, we can only wait scenes of later chapters.

Trenblastoise
07-10-2015, 02:53 AM
I'm 52 and feel that it's worse for ANYONE, male or female, who is young (teens, 20s) to lose hair. Luiza, you and I are both not at the point of needing to wear hair, so we truly do not know how we are going to feel when (if) we get there. If it were common to see women with shaved/bald heads, I don't think it would be as easy as you think to just shave it off. We, like men, would need good facial aesthetics to pull it off. I, for one, do not have that and would NEVER, EVER walk around bald in public. Plus, we have the advantage of wearing makeup to detract from facial flaws, whereas men do not. My son is 20 and losing hair fast. It's going to be tough for him to pull off the bald look. I feel way worse for him than I do for myself. I, too, feel far worse for all those who are having their youth robbed from them due to this disease. I had mine with a full head of hair, and I wish to God everyone I read about on these forums did too.

Yeah this is pretty much on point with what I think. What I am trying to say is there is a difference between how you feel, the emotional pain you take, and the consequence. I do agree, the younger you are the harder as well.


First, I wouldn't see any problem if I met a man who wears a hair system (a wig would be weird though. I find it weird even for women). You guys say it is seen as ridiculous for a guy to use a piece but trust me, it is not. It just means you rather have hair and you don't like the shaved look.
I've seen many men saying they would lose their masculinity if they wore a hair system LOL
I think you guys kind of start losing your confidence and stop approaching women and then are not able anymore to realise the way we think. I can tell you 90% of girls won't mind if you wear hair. You guys are the ones who create a scenario in your minds where a girl will dump you when she finds out you are wearing a piece. If you wear hair and shows confidence as you weren't wearing anything, we will not mind.
I understand it's not just like "shave it off and done, solved!". I know a great body helps. But I am in good shape and it wouldn't help much having a good body but being bald when you are a girl hahah
I was thinking about wearing hair but I still have quite "a lot" of my bio hair to just jump into that route. It is so hard to decide when you are in the middle of the line :(

The girls who shave it off and are happy with it are usually girls that don't suffer from hair loss haha I wanted to shave my head once in life to feel how it is but not because I have to! That's the point, we feel abnormal and sick :( I've never seen a girl going through hair loss and accepting the idea of shaving.

Everyone has to be confident, no matter if they are woman or man. I can make boys come to me without moving a finger but I can't make them stay when I feel shit all the time. I'm having some problems with my boyfriend lately cause I'm always moody because of my hair and even though he doesn't see any problem he tells me I'm always pretty but much more when I'm confident. That's the whole point. :)

Maybe it is somewhat geographic but the girls here dig long hair usually. I don't know precisely how they would feel about men wearing hair systems but I can imagine they think it is "weird". I am glad you at least have it easy to pick up boys and it is about your own mindset to keep them.

Anyway thanks for your posts, leaving this thread now. Hope these companies figure out something. Take care:)

Vox
07-10-2015, 04:23 AM
... whereas you are genetically programmed to look like a walking corpse and there is nothing you can do about it
Perhaps true but brutal to say it nonetheless. :D

lupero83
07-10-2015, 06:09 AM
Maybe it's a cure
In this podcast replicel he said it was a matter of frequency and dosage.

http://www.midasletter.com/midas-letter-financial-radio-podcast/replicel-life-sciences-inc-tsx-vrp-vp-lee-buckler-podcast-interview/
You can not compare this with chlorine dioxide and scams

Never before have we seen serious phase 2 trials

Sorry for my bad English

JayM
07-10-2015, 06:51 AM
If it makes all follicles androgen resistant and no more hairs end up falling out because of androgenic alopecia then it's a cure of the symptoms if you're at NW1 and decide to get this done. Not that I think anyone would because you would only realise once you're thinning. But to be fair society's habbits can change if they know a preventative treatment is out there. 5k is 5k when your father and uncle are nw7's right.

Again that interview was posted on the replicel thread. I would tell anyone here who isn't familiar go there and read it. Might know where we are at.

We have products in phase 2 right now for hairloss so I dunno what you mean there.

karxxx
07-10-2015, 08:11 AM
this replicell
useless
norwood7
I just hope Burhan university
Hair Stem Cells

burtandernie
07-10-2015, 04:57 PM
Why anyone would even mention the word MPB and cure in the same sentence I dont know. What proof is there it cures anything? You would think after hundreds of years people would be a bit cautious about ever claiming something cures MPB other than snake oil salesman.
When this is proven to work and its factual that MPB has been cured in many men than maybe let me know. Until then its all a pipe dream as its been the last hundred years

Swooping
07-10-2015, 07:48 PM
That's great Fievel Mousekewitz is very happy.

hellouser
07-11-2015, 12:58 AM
Why anyone would even mention the word MPB and cure in the same sentence I dont know. What proof is there it cures anything? You would think after hundreds of years people would be a bit cautious about ever claiming something cures MPB other than snake oil salesman.
When this is proven to work and its factual that MPB has been cured in many men than maybe let me know. Until then its all a pipe dream as its been the last hundred years

One of my coworkers told me to try meditation to treat my tinnitus....

I find that pretty insulting.

People are just taking us for a ride and make us into a joke.

Desmond84
07-12-2015, 01:14 AM
Did Replicel really use the word "Cure". Oh my. Is this the Replicel hype 2.0 starting to form!

I honestly didn't think we would be in this situation in 2015! How disappointing.

At least give us a new breed of rats with an afro! All that research could surely be put into some use. Right guys LOL

http://4.bp.blogspot.com/-29ccKscFA6s/T5sA98DXejI/AAAAAAAAAFo/Vj4yeZZfBKE/s1600/Afro+Mouse.jpg

thejack
07-12-2015, 02:49 AM
One of my coworkers told me to try meditation to treat my tinnitus....

I find that pretty insulting.

People are just taking us for a ride and make us into a joke.

How is that insulting?

Sogeking
07-12-2015, 03:44 AM
Did Replicel really use the word "Cure". Oh my. Is this the Replicel hype 2.0 starting to form!

I honestly didn't think we would be in this situation in 2015! How disappointing.

At least give us a new breed of rats with an afro! All that research could surely be put into some use. Right guys LOL


I think they are playing semantics here or trying to push their own definition of cure.
They stated on couple of occasions that their aim is to "immunize" follicles susceptible to hair loss by injecting their DSC cells from the donor region immune to DHT. that way they would halt the hair loss but won't offer much in terms of regrowth.
However so far the effect of immunization that is supposedly the direct result of their treatment is unproven.

baldybald
07-12-2015, 03:52 AM
This is hair loss guys! It is a beast and difficult to find a solution that easily. Can we get a cure in 10 years? I do not think so :(

breakbot
07-12-2015, 04:53 AM
One of my coworkers told me to try meditation to treat my tinnitus....

I find that pretty insulting.

People are just taking us for a ride and make us into a joke.

Haaha man you made my day!! Let the people laugh at you. You deserve it.

It's2014ComeOnAlready
07-12-2015, 02:01 PM
Did Replicel really use the word "Cure". Oh my. Is this the Replicel hype 2.0 starting to form!

I honestly didn't think we would be in this situation in 2015! How disappointing.

At least give us a new breed of rats with an afro! All that research could surely be put into some use. Right guys LOL.

"Cure" is a big word to throw around. For many, if it means never losing hair again, then that's a cure.

Full reversal is definitely something different.

Tenma
07-12-2015, 02:53 PM
"Cure" is a big word to throw around. For many, if it means never losing hair again, then that's a cure.

Full reversal is definitely something different.

+1

BoSox
07-12-2015, 03:46 PM
Hair line restored in 3 years or less? Seems too good to be true. I hope we know for sure in the next year.

burtandernie
07-12-2015, 05:35 PM
I dont think we are far from a cure in terms of never losing anymore hair. I mean its almost possible with existing stuff for most people. The next batch of stuff maybe with CB should be able to stop MPB at the very least hopefully a lot more than that.

mcarpenter089
07-13-2015, 02:52 AM
Hey bro, i have tinnutus also. It really sucks being a sufferer of hair loss, and dealing with tinnutus which has no cure!!!!! Looks like we are a pretty rare breed of screwed. I hope to god 2018 will be a cure even tho the odds are against us, god is with us! Keep hope alive.

Gremlin142
07-13-2015, 02:41 PM
Hair transplants cost so much today because of the amount of time, material and people that are put into making them successful. If they could remove a piece of the scalp, re-grow cells from it and then re-inject my guess is this is going to be much less labour intensive. If that is the case, then why not sell the treatment for a much lower price? Economies of scale. Apple is not the biggest company in the world cause it sells iPhones for $10,000 a piece. Get real, use your head for something other than losing hair.

TooMuchHairWontKillYou
07-13-2015, 02:48 PM
Hair transplants cost so much today because of the amount of time, material and people that are put into making them successful. If they could remove a piece of the scalp, re-grow cells from it and then re-inject my guess is this is going to be much less labour intensive. If that is the case, then why not sell the treatment for a much lower price? Economies of scale. Apple is not the biggest company in the world cause it sells iPhones for $10,000 a piece. Get real, use your head for something other than losing hair.

Learn enonomics... supply/demand

Dimoxynil
07-13-2015, 04:06 PM
Hair transplants cost so much today because of the amount of time, material and people that are put into making them successful. If they could remove a piece of the scalp, re-grow cells from it and then re-inject my guess is this is going to be much less labour intensive. If that is the case, then why not sell the treatment for a much lower price? Economies of scale. Apple is not the biggest company in the world cause it sells iPhones for $10,000 a piece. Get real, use your head for something other than losing hair.

I phones may not be 10k but they're extortionately expensive compared to other phones that basically do the same thing.

Trouse5858
07-13-2015, 06:28 PM
iPhones are "cheap" because they're made for pennies on the dollar through outsourced borderline sweatshop labor.

Im not sure hair transplants could follow a similar business model.

JayM
07-13-2015, 06:41 PM
Just to add iPhones aren't really the best in terms of specs for the price you pay. As with anything, just do your research before you commit.

nohawk
07-13-2015, 06:58 PM
who gives a shit ...

nameless
07-13-2015, 08:38 PM
Why in the &%$# are we talking about cell phones?

Gremlin142
07-14-2015, 09:10 AM
Learn enonomics... supply/demand

How many more people could buy the treatment for $5000 than could for $30,000? Have you ever looked at the supply and demand curves and figured out where the profit maximization point is? (Hint: It's not in the top left corner) Thank you for educated input....

hellouser
07-14-2015, 09:43 AM
I phones may not be 10k but they're extortionately expensive compared to other phones that basically do the same thing.

That's a TERRIBLE example. Everyone knows Apple's products are artificially inflated;

$3,000 for a computer with specs of a PC that costs $1,500. They charge $600 for a 32gb RAM upgrade when in reality it costs only $200 (for better quality ram too).

BoSox
07-14-2015, 10:44 AM
Cost is the last thing on my mind. We need a cure, we can discuss cost later.

TooMuchHairWontKillYou
07-14-2015, 11:34 AM
How many more people could buy the treatment for $5000 than could for $30,000? Have you ever looked at the supply and demand curves and figured out where the profit maximization point is? (Hint: It's not in the top left corner) Thank you for educated input....

First of all muuch more people will afford 5k than 30k (including me)
Then.. I'm pretty good in economics unlike English lol :)

I said supply/demand because it is the only real reason why RCH-01 could have high price, not the labour and other factors. They wont handle quantity demanded on the low price.

And sorry if I was rude in previous comment :)

brocktherock
07-14-2015, 02:06 PM
Look at boob jobs and ass implants. That's something that answered countless women's prayers and it still took a while to catch on. I don't think the majority of bald guys know what replicel is and probably won't until it blows up

joachim
07-19-2015, 04:44 PM
i found this comment on the other HS forum:

On March 20th at 12:00 noon local time, RepliCel’s Chief Medical Officer, Dr. Rolf Hoffmann and licensing partner Shiseido Company Ltd.’s, Dr.’s Manabu Ohyama and Jiro Kishimoto, will be presenting at the 14th Congress of the Japanese Society for Regenerative Medicine (JSRM) 2015 in Yokohama, Japan. Leading the discussion will be Dr. Manabu Ohyama who will talk on the “Use of human induced pluripotent stem cells for the generation of hair inductive dermal cells.”



this was news to me. i thought the recent news article confused iPS cells with the normal DSC cells replicel is using, but now it seems, half of the article is true.
so it seems shisheido is indeed experimenting with iPS cells, too.
this could be huge, in my opinion. on the other side, it may tell us that replicels current DSC cell multiplication process isn't sufficient yet, otherwise there wouldn't be a need to go the way through iPS cells.
to date we still don't know how efficient the DSC multiplication works. are they facing the same gene expression problems like with DP cells or did they find a workaround for that? if we only could know.

hellouser
07-19-2015, 06:53 PM
Look at boob jobs and ass implants. That's something that answered countless women's prayers and it still took a while to catch on. I don't think the majority of bald guys know what replicel is and probably won't until it blows up

They didn't catch on because those procedures are out of vanity. Baldness solutions are trying to retain something we've been born with and take away from our identity.

nameless
07-19-2015, 07:22 PM
i found this comment on the other HS forum:

On March 20th at 12:00 noon local time, RepliCel’s Chief Medical Officer, Dr. Rolf Hoffmann and licensing partner Shiseido Company Ltd.’s, Dr.’s Manabu Ohyama and Jiro Kishimoto, will be presenting at the 14th Congress of the Japanese Society for Regenerative Medicine (JSRM) 2015 in Yokohama, Japan. Leading the discussion will be Dr. Manabu Ohyama who will talk on the “Use of human induced pluripotent stem cells for the generation of hair inductive dermal cells.”



this was news to me. i thought the recent news article confused iPS cells with the normal DSC cells replicel is using, but now it seems, half of the article is true.
so it seems shisheido is indeed experimenting with iPS cells, too.
this could be huge, in my opinion. on the other side, it may tell us that replicels current DSC cell multiplication process isn't sufficient yet, otherwise there wouldn't be a need to go the way through iPS cells.
to date we still don't know how efficient the DSC multiplication works. are they facing the same gene expression problems like with DP cells or did they find a workaround for that? if we only could know.

We will find out in October at the hair loss congress.

And I think that this year would be a better year than last year was to send one of us to the congress to gather information. I do believe that this year will be the year that a cure for hair loss will be announced. Finally!

lupero83
07-20-2015, 05:31 AM
replicel has posted this link on your facebook http://www.cosmeticsdesign-asia.com/Formulation-Science/We-ve-found-a-cure-for-baldness-says-Shiseido

BoSox
07-20-2015, 06:07 AM
replicel has posted this link on your facebook http://www.cosmeticsdesign-asia.com/Formulation-Science/We-ve-found-a-cure-for-baldness-says-Shiseido

They better freaking deliver. We've heard those "baldness cure" claims for far to long. It's about time we have the real thing!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! !!!!!!!!!!!

baldybald
07-20-2015, 07:14 AM
They better freaking deliver. We've heard those "baldness cure" claims for far to long. It's about time we have the real thing!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! !!!!!!!!!!!
Well, the good thing that they understand the cause of hairloss and how to fix it according to their video and that what makes me optimistic. In the case of Aderans, it did not show a lot of explanation of their work. Oh hey BoSox you finally changed your profile picture!!

Hair Bear
07-20-2015, 08:50 AM
The article follows the same format as every other touted "cure" and offers very little substance at all therefore I would not pin my hopes onto this article in itself.

I'm very hopeful that the research pays off and we do see a cure by said date but realistically its a big ask. (one must also consider worldwide adaptation, price and general accessibility in your region by skilled professional.
Sadly by three years time I will be fully sporting the old man look on top and given that I could never commit to the shave it I'm stuck playing solitaire on the weekdays and the fiddle on the weekends. :D

BoSox
07-20-2015, 11:19 AM
Well, the good thing that they understand the cause of hairloss and how to fix it according to their video and that what makes me optimistic. In the case of Aderans, it did not show a lot of explanation of their work. Oh hey BoSox you finally changed your profile picture!!

Agreed.

rdawg
07-20-2015, 11:28 AM
Are they going to be at the world hair congress in Miami? hopefully someone around their can go!

I'd imagine they have something to present then, as the trials should be starting up soon in the US.

very intriguing company and product, had pretty mediocre results after proof of concept but it was 3 years ago, they clearly changed something or at least saw an improvement later on, as a company doesnt usually invest alot of money like that for no reason.

definitely a big name to watch, other than CB, SM, BIM, SETI etc. 2015 is an interesting year to say the least!

mcarpenter089
07-31-2015, 11:25 AM
Really?! Have I just read the title of this post and the first line is sheishedo?

Please you have over 200 posts have you not visited the cutting edge section?

I think you should just be optimistic man.

JayM
07-31-2015, 01:09 PM
I'm very optimistic about new treatments. I was annoyed because of people reading that news article and loads of new threads opening up like the cure is here. Despite the fact having a massive in depth thread about replicel. You can find all the information you want in the replicel section it just takes time to read.

I have every hope replicel works believe me.

Renee
07-31-2015, 01:30 PM
I hope it works but I'm very cautious. Look at how much difficultly tsuji, jahoda/christiano, linder/lauster/ atac are having in trying to crack the final stage (I'm praying they have now) It may be a maintenance cure but that will take a very long time to follow patients and make that claim.

Gremlin142
01-28-2016, 06:01 PM
That's a TERRIBLE example. Everyone knows Apple's products are artificially inflated;

$3,000 for a computer with specs of a PC that costs $1,500. They charge $600 for a 32gb RAM upgrade when in reality it costs only $200 (for better quality ram too).

Eat your words. Right again! However, I really appreciate your interview with Histogen. Top notch, great info received.

tedwuji
02-04-2016, 02:04 PM
If it takes 30 years I'll be 52 when it comes out haha not good news :( I wont even care this much about hair (or maybe I wll)

time to buzz it like GI Jane!

jamie77
07-19-2016, 07:19 AM
I noticed I was going bald, I panicked and turned the internet upside down in search of a solution and tried lots of products and weird things but none worked. a friend who used to tease me about the hair (in a bid to tease me further) bought a product from Africa during his travels and he mockingly gave me as a present.I tried it and the result is unbelievable. infact he had to call his contacts in Africa to get in touch with the manufacturers. I know how frustrating and confidence-sapping being bald is that's why I took this painstaking mission to reveal to any who wants to try it. you can contact the manufacturers on (abiomoigho@gmail.com)I hope this message helps.

Dench57
07-19-2016, 07:23 AM
I noticed I was going bald, I panicked and turned the internet upside down in search of a solution and tried lots of products and weird things but none worked. a friend who used to tease me about the hair (in a bid to tease me further) bought a product from Africa during his travels and he mockingly gave me as a present.I tried it and the result is unbelievable. infact he had to call his contacts in Africa to get in touch with the manufacturers. I know how frustrating and confidence-sapping being bald is that's why I took this painstaking mission to reveal to any who wants to try it. you can contact the manufacturers on (abiomoigho@gmail.com)I hope this message helps.

Is it by any chance a Nigerian prince who just needs my account number and PIN to send me $100k?

joachim
07-19-2016, 11:06 AM
I noticed I was going bald, I panicked and turned the internet upside down in search of a solution and tried lots of products and weird things but none worked. a friend who used to tease me about the hair (in a bid to tease me further) bought a product from Africa during his travels and he mockingly gave me as a present.I tried it and the result is unbelievable. infact he had to call his contacts in Africa to get in touch with the manufacturers. I know how frustrating and confidence-sapping being bald is that's why I took this painstaking mission to reveal to any who wants to try it. you can contact the manufacturers on (abiomoigho@gmail.com)I hope this message helps.

lol @ all nigerian scammers. it couldn't be more obvious.

SebaURU
07-19-2016, 11:08 AM
Is it by any chance a Nigerian prince who just needs my account number and PIN to send me $100k?

Must be the same ;)

allTheGoodNamesAreTaken
07-19-2016, 08:08 PM
I noticed I was going bald, I panicked and turned the internet upside down in search of a solution and tried lots of products and weird things but none worked. a friend who used to tease me about the hair (in a bid to tease me further) bought a product from Africa during his travels and he mockingly gave me as a present.I tried it and the result is unbelievable. infact he had to call his contacts in Africa to get in touch with the manufacturers. I know how frustrating and confidence-sapping being bald is that's why I took this painstaking mission to reveal to any who wants to try it. you can contact the manufacturers on (abiomoigho@gmail.com)I hope this message helps.


**** off liar.

yagazooci
07-21-2016, 10:19 AM
http://finance.yahoo.com/news/replicels-cell-therapy-pattern-baldness-120000877.html

SebaURU
07-21-2016, 11:27 AM
http://finance.yahoo.com/news/replicels-cell-therapy-pattern-baldness-120000877.html

They don`t inform when is going to start this clinical trial? :(

I hope it works!
If trials starts in 2017 and works, when do you think would be launched to the market?

SebaURU
07-21-2016, 11:39 AM
More information
http://replicel.com/wp-content/uploads/2015/02/Phase-I-Interim-Analysis-Nov-2012.pdf

Vox
07-21-2016, 12:39 PM
More information
http://replicel.com/wp-content/uploads/2015/02/Phase-I-Interim-Analysis-Nov-2012.pdf
I am afraid this is old news. They talk about Phase IIb clinical trial expected to start in late 2012 ...

hairy
07-21-2016, 04:27 PM
It says "starting now" in there. More here:

http://www.hairlosscure2020.com/so-its-shiseidoreplicel-versus-rikentsuji-at-the-kobe-biomedical-innovation-cluster-kbic/






They don`t inform when is going to start this clinical trial? :(

I hope it works!
If trials starts in 2017 and works, when do you think would be launched to the market?

SebaURU
07-22-2016, 03:03 AM
It says "starting now" in there. More here:

http://www.hairlosscure2020.com/so-its-shiseidoreplicel-versus-rikentsuji-at-the-kobe-biomedical-innovation-cluster-kbic/

Replicel on Twiteer posted they are starting clinical trials in second half of 2016

nameless
07-22-2016, 10:19 AM
I don't understand why people are excited about this. Replicel gave some results from an earlier study and the regrowth was lousy. They do not even grow as much hair as minox + propecia.

KOORII
07-29-2016, 06:07 PM
Actually they're looking for volunteers if you live in Germany or Austria
http://replicel.com/contact-us/clinical-trial-information/

KOORII
07-29-2016, 06:08 PM
Actually they're looking for volunteers if you live in Germany or Austria
http://replicel.com/contact-us/clinical-trial-information/

SebaURU
07-31-2016, 05:31 AM
I really don't know what to think about Replicel. They talk about 5% 19,6% and 24% of increasing hair, but you have to consider what amount of hair are in the baseline. For example, if in the baseline you have only 100 hairs in all your scalp and the increase is 24%, that´s shit! and increasing doses doesn't really means that will increase the amount of hair.

ShookOnes
07-31-2016, 07:44 PM
I really don't know what to think about Replicel. They talk about 5% 19,6% and 24% of increasing hair, but you have to consider what amount of hair are in the baseline. For example, if in the baseline you have only 100 hairs in all your scalp and the increase is 24%, that´s shit! and increasing doses doesn't really means that will increase the amount of hair.


24% is a godsend to pretty much everyone else so..