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35YrsAfter
07-07-2013, 10:17 AM
Reputable hair restoration physicians will generally avoid doing a hair transplant on a young man below the age of 29. A lot of young people 17-29 are frustrated that their hair is thinning and/or receding and existing products like Rogaine, Propecia and Avodart generally do not provide (IMO/IPO's) substantial improvement. At Dr. Cole's office, we have encouraged patients to use ACell and PRP treatments during their hair transplant surgeries. We have found that ACell and PRP improves healing. Our recent repair patient came in for photos last week and was shocked at the improvement in his crown area. He had been using Avodart since approx. 2003. He noticed a big improvement in hair shaft diameter after his 2011 ACell / PRP treatment in 2011. Dr. Cole uses the Angel system and his latest PRP adjustments have provided some encouraging results for hair loss sufferers.

Have a look at this video. It is in 720p and you can adjust the quality from the default You Tube setting by hitting the lower "gear" icon. Set to 720p. Also hit the "full screen" button on the lower far right. You can clearly see the improvement in hair shaft diameter. This compares the 2007 photo to the 2013 photo taken just before his 2013 ACell PRP treatment. Please also consider that MPB is progressive so his thinning area should be worse after 6 years rather than improved.

Here is the link to the Video (https://www.youtube.com/watch?v=FlZ_osaP5Yg&feature=c4-overview&list=UUf3bYuBt1lHSrVTZjW1TReA)

35YrsAfter works at Dr. Cole's office
chuck@forhair.com
www.forhair.com (http://www.forhair.com)
Please feel free to email me with any questions

Breaking Bald
07-07-2013, 12:03 PM
Wow...those results are very poor and unclear...

Dan26
07-07-2013, 12:07 PM
brutal...

Breaking Bald
07-07-2013, 12:12 PM
Spend a fortune on painful, bloody injections and get hardly any noticeable results, yeah sign me up...

The before and after picture is completely useless as well. The second 'results' picture is with all the hair combed over the bald spot. Pathetic :rolleyes:

35YrsAfter
07-07-2013, 01:14 PM
Spend a fortune on painful, bloody injections and get hardly any noticeable results, yeah sign me up...

The before and after picture is completely useless as well. The second 'results' picture is with all the hair combed over the bald spot. Pathetic :rolleyes:

The 2007 and the 2013 photos were scaled to the same head size. IF you open the video on a decent computer with good graphics and adjust the quality as I suggest, there is NO question that there is a significant improvement. Male pattern baldness nearly always gets progressively worse. 6 years later there is an improvement in hair shaft diameter. Our patient had been taking Avodart since 2003 and didn't notice a difference in hair shaft thickness and quality until he began having ACell/PRP treatments.

Look at the image below where I circle the two You Tube settings that will offer the two sharpest views. Anyone on a decent computer viewing the 2007 and 2013 side by side can clearly see the improvement in hair shaft diameter.

I challenge you to look at this video again set to the highest quality. The hair does not completely cover the hair as it exits the scalp on either photo. They can be clearly seen. Come back here and tell me you don't see a difference after adjusting the videos quality and you will lose credibility here because the improvement is plain as day to anyone with even a modicum of visual discernment.

35YrsAfter works at Dr. Cole's office
www.forhair.com (http://www.forhair.com)
chuck@forhair.com

greatjob!
07-07-2013, 01:20 PM
I'm curious as to what percentage of people you see responding to the prp/acell treatments. I was contemplating it a few years ago but from what I saw a very small percentage of patients see any improvement and when they did it was very marginal. I just can't see spending $1000-$2000 every 6-12 months to undergo a treatment that more than likely won't do anything for me and if it does it will be a very small improvement

ryan555
07-07-2013, 01:22 PM
Some of you guys just sit around on the Internet all day complaining about your hair loss and rejecting anyone who attempts to try something new to help patients. PRP is not a miracle cure but it is a viable treatment to help one maintain hair, and it definitely has improved the thickness and quality of my existing hair. I applaud Dr Cole and any other doctors who are willing to try non-traditional things to help their patients. We should really stop bad mouthing these guys because they are not the enemy.

Breaking Bald
07-07-2013, 01:30 PM
Yeah there is a difference but it is very minimal and like I say the before/after pic is not great. The first pic is with the hair messed up, second pic the hair is brushed over the bald spot. Are there any potential side effects with this treatment? I've heard it is very bloody and messy?

35YrsAfter
07-07-2013, 01:37 PM
Some of you guys just sit around on the Internet all day complaining about your hair loss and rejecting anyone who attempts to try something new to help patients. PRP is not a miracle cure but it is a viable treatment to help one maintain hair, and it definitely has improved the thickness and quality of my existing hair. I applaud Dr Cole and any other doctors who are willing to try non-traditional things to help their patients. We should really stop bad mouthing these guys because they are not the enemy.

Thanks ryan555:

Our patient posted in the Hair Transplant area of The Bald Truth Forum. Here are his remarks:

Ljpviper:
"The procedure takes like total maybe two hours. The numbing of the area is a little painful, but not too bad. I washed my hair two days after and my scalp is still a little sore still, nothing major.

I noticed an improvement 2-3 weeks after. My hair is normally brown, it turns very dark brown,almost black. The diameter of the hair shafts increase in the same time frame. I would say month 1 to month 8 are the best in hair quality.

After month 8 it seems to lose some color and thickness. As stated the procedure in 2012 worked better than 2011. I told chuck I may be in the Atlanta area in the next few months. I will stop by the office so they can take some photos."

The Video (https://www.youtube.com/watch?v=FlZ_osaP5Yg&feature=c4-overview&list=UUf3bYuBt1lHSrVTZjW1TReA)

35YrsAfter works at Dr. Cole's office
www.forhair.com (http://www.forhair.com)
chuck@forhair.com

35YrsAfter
07-07-2013, 02:22 PM
Yeah there is a difference but it is very minimal and like I say the before/after pic is not great. The first pic is with the hair messed up, second pic the hair is brushed over the bald spot. Are there any potential side effects with this treatment? I've heard it is very bloody and messy?

Dr. Cole began using PRP because it was proven to promote healing:
Emory Hospital (http://www.emoryhealthcare.org/sports-medicine/procedures/advanced-techniques/prp-therapy.html)

ACell has proven itself as a regenerative product and was approved by the FDA as such. At the very least, ACell improves vascularization and reduces hypopigmentation of the donor extraction sites. We have observed ACell's regenerative advantages as well.

I began losing my hair at an early age and would have had ACell and PRP treatment back then if it had been available. Insignificant improvement?... Our patient told me he was pleasantly shocked at his improved hair caliber. If he thought the improvement was insignificant, I doubt he would return every year for more ACell / PRP treatments. Untreated, MPB over a 6 year span will nearly always progress toward significant visible hair loss. The fact that our patient's hair looks better after 6 years is noteworthy.

To me this is huge in light of the promises of Histogen and other technologies that haven't materialized.

There are questions. Does Rogaine or Avodart enhance the effectiveness of ACell/PRP? When Dr. Cole and other top hair restoration physicians get a significant result, the thought process is: How can we improve that result?

To me this progress is exciting, particularly for men between the age of 17 and 29. I remember as a young man when I first noticed my hair loss. It was like my life fast-forwarded from young to middle age in a matter of a few years.

If we can hold back hair loss in young men, we will see an improvement in self confidence and quality of life.

35YrsAfter works at Dr. Cole's office
www.forhair.com (http://www.forhair.com)
chuck@forhair.com

Dan26
07-07-2013, 03:07 PM
Considering the cost, and the fact the patient was on avodart and rogaine, it doesn't seem to add to much to the arsenal of a young guy with aggressive hairloss. The fact there were at least considerable positive results is encouraging though. I personally would love to see it's effectiveness without fin/minox, because the fact that it gave a long time sufferer (who has aggressive loss), cosmetically significant results, is encouraging. But again, the cost, and the fact that we haven't gauged its effectiveness as a true stand alone treatment, is unfortunate.

PayDay
07-07-2013, 03:34 PM
In all honestly the pictures do suck, but people don't have to be so hostile to make their point. It's clear that the guy in the video is pleased, why try to bring him down?

35YrsAfter
07-07-2013, 03:45 PM
Considering the cost, and the fact the patient was on avodart and rogaine, it doesn't seem to add to much to the arsenal of a young guy with aggressive hairloss. The fact there were at least considerable positive results is encouraging though. I personally would love to see it's effectiveness without fin/minox, because the fact that it gave a long time sufferer (who has aggressive loss), cosmetically significant results, is encouraging. But again, the cost, and the fact that we haven't gauged its effectiveness as a true stand alone treatment, is unfortunate.

Our Patient has used Rogaine for many years. He began using Avodart in 2003. He didn't notice a significant increase in his hair shaft diameter before he began with the ACell / PRP treatments in 2010.

To me it's not hard to imagine an 18 year old who is beginning to show MPB thinning to "go back in time" 4 years with PRP / ACell treatments. Imagine regular treatments providing a gradual improvement over time rather having things go all to hell in the opposite direction to Norwood 5 or 6 by age 30. Perhaps this is overly optimistic, but knowing Dr. Cole, he is going to continue to improve these treatments.

Look on the bright side, when I was a teenager, there was absolutely no hope for young men with hair loss. I still recall the sinking feeling. Rogaine wasn't even available.

35YrsAfter works at Dr. Cole's office

Breaking Bald
07-07-2013, 04:07 PM
In all honestly the pictures do suck, but people don't have to be so hostile to make their point. It's clear that the guy in the video is pleased, why try to bring him down?

I agree, I didn't mean to come across as hostile so I apologise, I've just had a really bad few days dealing with hair loss and honestly I'm just sick to death of staring at before/after pics, researching treatments and being dragged down with all of the disagreements, misinformation and confusion within this industry. I'm 23 and I dread to think how many countless hours of my life I have spent looking for answers, only to be disappointed :/

35YrsAfter
07-07-2013, 04:36 PM
In all honestly the pictures do suck, but people don't have to be so hostile to make their point. It's clear that the guy in the video is pleased, why try to bring him down?

Honestly, the photos are excellent. The video is in 720p. By default, You Tube shows videos at a low resolution. By setting the video to 720p hi-def and hitting the fullscreen button, the photos are very clear on a reasonably decent computer and monitor.

I heard complaints about how the hair is combed. At high resolution the hairs can CLEARLY be seen exiting from the scalp and the shafts can clearly be seen to be thicker.

Please look at the attached image and follow the instructions on the image. Watch the video again at 720p set to full screen. It is obviously clear that there is improvement in hair shaft diameter. The hair shafts are NOT concealed where they exit the scalp.

Take a look again with the proper settings. VIDEO (https://www.youtube.com/watch?v=FlZ_osaP5Yg&feature=c4-overview&list=UUf3bYuBt1lHSrVTZjW1TReA)

35YrsAfter works at Dr. Cole's office

StayThick
07-07-2013, 04:53 PM
There are no studies or efficient evidence that PRP has any positive impact on hair.

PRP has been available for many years in other applications. The application of hair is still relatively new with more and more doctors no longer even offering the procedure. That alone speaks volumes.

I, myself had it done 6 months ago. I can't say it did much of anything, not even maintenance. For $1k, it's not worth me trying it again. For those that wish to try it, by all means. I was desperate for anything to work so I had it done.

I don't regret it, but for those looking for regrowth or for that "home run" treatment... This is not for you. Save your money.

0ptimist
07-07-2013, 05:03 PM
Chuck,

You seem to be avoiding the question as to the efficacy of PRP + Acell in general. It's nice to have an example, but one case study is insufficient to make a judgment. For all we know, Viper may be only one out of a hundred patients who saw improvement. Or his result could be typical. We just don't know with the limited information you are providing.


The fact that you won't given any indication as to what percentage of Dr. Cole's patients achieve success with PRP + Acell is troubling. Any additional information would be appreciated.

Thanks.

0ptimist
07-07-2013, 05:04 PM
StayThick, can you tell us any more information about your procedure. Did it involve both PRP + Acell?

Breaking Bald
07-07-2013, 05:18 PM
Chuck,

You seem to be avoiding the question as to the efficacy of PRP + Acell in general. It's nice to have an example, but one case study is insufficient to make a judgment.

+1
10 char

35YrsAfter
07-07-2013, 06:37 PM
Chuck,

You seem to be avoiding the question as to the efficacy of PRP + Acell in general. It's nice to have an example, but one case study is insufficient to make a judgment. For all we know, Viper may be only one out of a hundred patients who saw improvement. Or his result could be typical. We just don't know with the limited information you are providing.


The fact that you won't given any indication as to what percentage of Dr. Cole's patients achieve success with PRP + Acell is troubling. Any additional information would be appreciated.

Thanks.

Dr. Cole began using ACell because it's an FDA approved regenerative product that improves the appearance of FUE donor extraction sites. It reduces hypopigmentation and improves blood vessel formation. We are also seeing on average around 50% follicle regeneration in the donor areas where ACell is used. I believe Dr. Cole began using PRP to improve healing.

I got an email on Saturday from a patient who just had beard hair extractions. He said the extraction sites disappeared after 4 days, and healing was much quicker than his experience with previous surgeries where ACell and PRP were not used.

Dr. Cole recently received an invitation to participate in a PRP study. Even the doctor to doctor hair transplant publication we receive, recently commented on the lack of PRP studies. There really aren't any formal studies that I'm aware of. Should there be? Of course. I was excited about our patient's improvement. He is excited. It worked for him and we will do our best to determine how to make these treatments as effective as possible.

Of course it needs to be determined which PRP formulation is most effective. Dr. Cole uses the Angel system that allows for many variations in the concentration. Also, how effective is PRP without ACell? Any study needs to be standardized. Do Avodart and Rogaine enhance the effects? These are questions that need to be answered.

35YrsAfter
07-07-2013, 07:02 PM
There are no studies or efficient evidence that PRP has any positive impact on hair.
PRP has been available for many years in other applications. The application of hair is still relatively new with more and more doctors no longer even offering the procedure. That alone speaks volumes.

When PRP treatment doesn't work, it benefits everyone to determine why. I posted our patient interview so he could talk about medications he currently uses. In the video, he mentions Rogaine and Avodart. He also mentioned that he had the best result from the treatment he had in 2012 as opposed to his first treatment in 2011. Dr. Cole used a different PRP / ACell formulation in 2012.

I was 18 once and remember the depressing proposition of being bald by the time I was 30. It was a sinking sense of despair, like years were about to be trimmed off of my life. Most reputable hair restoration physicians won't perform a hair transplant on any man under 26-29. I'm thinking from my own perspective... If I were 21 again (in 2013), I would consider Rogaine and PRP /ACell treatment. I'm not sure about Avodart but there are many people who swear by it. I'm considering ACell / PRP treatment at my advanced age. I need help in my donor area with regards to density.

35YrsAfter works at Dr. Cole's office

0ptimist
07-07-2013, 07:04 PM
You gave a percentage for donor regeneration with Acell, but we are asking for this kind of average with regards to PRP + Acell as a stand alone treatment.

Can you give us an estimate of the success rate for PRP + Acell as a stand alone treatment? I don't mean to be a broken record here, but this is kind of important for those who are considering the treatment.

35YrsAfter
07-07-2013, 07:14 PM
The other day at work I was depressed because of a remark someone made about my hair looking thin in the back. I'm still self conscious about the appearance of my hair. I'm a tough case. I went home that night and mentioned to my wife that I was feeling down about my hair and she said come to think of it, your hair really sucks, can I have a divorce?

Just kidding. She said, you look fine it's no big deal. It's great to have someone in your life who loves you the way you are. There ARE some great women out there and some women even find baldness sexy. I had a lady tell me that not long ago.

35YrsAfter works at Dr. Cole's office

35YrsAfter
07-07-2013, 07:24 PM
You gave a percentage for donor regeneration with Acell, but we are asking for this kind of average with regards to PRP + Acell as a stand alone treatment.

Can you give us an estimate of the success rate for PRP + Acell as a stand alone treatment? I don't mean to be a broken record here, but this is kind of important for those who are considering the treatment.

Tomorrow I will provide as much information on stand alone PRP / ACell success rates as we have available. Most of our patients who have PRP / Acell treatments receive it with their FUE surgery.

No broken record impressions here. People should be skeptical and ask questions.

35YrsAfter works at Dr. Cole's office

Conpecia
07-07-2013, 08:34 PM
I am in the Atlanta area and am 28 years old. I'm not too far along in my mpb (NW2.7 with thinning crown) and would love to benefit from this treatment even if that means simply keeping my hair as is. I take Rogaine foam and am experimenting with pgd2 blockers, but the only DHT blocker I can handle is keto. I'd gladly document my results in a similar fashion as the guy in the video. If nothing else it would give us another case study...

35YrsAfter
07-08-2013, 08:13 AM
Conpecia:

I will speak with Dr. Cole today and get more information. Dr. Cole didn't ask me to create a video in order to sell PRP / ACell treatments. I was excited about our patient's results as he is and decided to shoot and post the video on my own, to illustrate a point of study worthy of further investigation. In other words, over a 6 year period, this man's hair loss should have been worse, not improved. Can we duplicate this result? That's why I included in the video, mention of the medications our patient is taking.

Sorry to be repetitious, but the question in my mind relates to Rogaine and Avodart enhancing the effects of ACell / PRP treatments.

I just asked our RN how many patients we have seen in the last year having stand-alone ACell / PRP treatments. She told me 4, perhaps 5. As I mentioned earlier, Dr. Cole began using ACell and PRP because both products provide improved healing. In other words, nearly all of our patients who have received ACell / PRP treatments have had the treatments on their FUE surgery day.

ACell and PRP show great promise in my opinion. Further studies will definitely be worth the effort.

35YrsAfter works at Dr. Cole's office

0ptimist
07-08-2013, 04:14 PM
Thanks for the additional info. Chuck. We know Viper got good results. Do you have any indication as to the results of the other 3-4 people who had stand alone PRP + Acell treatment?

35YrsAfter
07-09-2013, 09:38 AM
Thanks for the additional info. Chuck. We know Viper got good results. Do you have any indication as to the results of the other 3-4 people who had stand alone PRP + Acell treatment?

We had five stand-alone ACell / PRP patients within the last year. I was able to reach two today by phone, other than our patient I posted. One of the men I spoke with said he noticed an improvement behind his hairline in the frontal area. He is a patient with reasonably thick hair on top and does the treatments for maintenance. Our other patient I spoke with on the phone noticed some benefit but nothing dramatic. I asked our two patients what medications they were taking. Both use Rogaine but neither use Propecia or Avodart.

We are seeing early growth and excellent healing when ACell and PRP are used on the day of FUE surgery. See 3 1/2 month post-op photo below. Our patient had 2840 FUE grafts placed on 03-20-13.

35YrsAfter also posts as CITNews and works at Dr. Cole's office
Cole Hair Transplant
1045 Powers Place
Alpharetta, Georgia 30009
Phone 678-566-1011
Please feel free to call or email me with any questions.

0ptimist
07-09-2013, 04:00 PM
Thanks for the information Chuck. Good to know your office is having success with the procedure.

antman
07-09-2013, 07:01 PM
You gave a percentage for donor regeneration with Acell, but we are asking for this kind of average with regards to PRP + Acell as a stand alone treatment.

Can you give us an estimate of the success rate for PRP + Acell as a stand alone treatment? I don't mean to be a broken record here, but this is kind of important for those who are considering the treatment.

I have some results for PRP

http://i.imgur.com/JKmXNME.png
http://i.imgur.com/wgJ2ebi.png

Source:
Enhanced effect of platelet-rich plasma containing a new carrier on hair growth (Takikawa et al, 2011)
Full study
https://www.dropbox.com/s/hxbnj9mf15tc8tz/Enhanced%20Effect%20of%20Platelet-Rich%20Plasma%20Containing%20a%20New%20Carrier%20o n%20Hair%20G.pdf

FearTheLoss
07-09-2013, 07:20 PM
so that's saying you should have 5 prp injections per 12 months?

35YrsAfter
07-10-2013, 06:04 AM
so that's saying you should have 5 prp injections per 12 months?

There is no question that PRP is effective. The question remaining is... How do we improve the results of PRP therapy? Dr. Cole uses ACell with his PRP and administers ACell / PRP mostly during FUE surgery because of the improved healing these two products provide our patients.

The benefits of ACell during FUE surgery include:
1.) Reduced hypopigmentation of the extraction sites.
2.) Increased blood vessel formation.
3.) Follicle regeneration 10% to 70% average around 50%

The benefits of PRP during FUE surgery include:
1.) Quicker healing
2.) Earlier transplanted hair growth
3.) Increase in hair shaft diameter overall.


Is PRP currently effective enough to justify the cost and inconvenience of multiple stand-alone treatments per year? IMO, I would personally consider one treatment per year. Other men and women with hair loss may be fine with two, three, perhaps four treatments per year.

35YrsAfter also posts as CITNews and works at Dr. Cole's office
Cole Hair Transplant
1045 Powers Place
Alpharetta, Georgia 30009
Phone 678-566-1011
Please feel free to call or email me with any questions.

0ptimist
07-14-2013, 09:26 AM
Chuck,

If you are seeing donor regeneration on that level, it is a monumental breakthrough in hair restoration.

Can you provide some before and after photographs documenting this regeneration?

35YrsAfter
07-15-2013, 07:36 AM
Chuck,

If you are seeing donor regeneration on that level, it is a monumental breakthrough in hair restoration.

Can you provide some before and after photographs documenting this regeneration?

We are working to improve the effectiveness of ACell. The patient in our most recent study healed so well that after 3 months the extraction sites could not be located even with bright lighting and magnifying loupes. In past studies there was minimal scarring but enough that under strong lighting and magnification, we were able to locate the extraction sites to see hair growing from them. More studies are in the works.

35YrsAfter also posts as CITNews and works at Dr. Cole's office
Cole Hair Transplant
1045 Powers Place
Alpharetta, Georgia 30009
Phone 678-566-1011
Please feel free to call or email me with any questions.