View Full Version : Topical Finasteride/RU

06-22-2013, 05:11 PM
Two questions. Is RU topical? and has anyone tried finasteride as a topical solution? As it could have less sides being more localized in the scalp? I am a chemist so I am quite interested in anyones experience


"The potency of RU58841 was comparable to that of hydroxyflutamide. From this result, topical application of RU58841, which is considered to be a potential therapy for skin diseases, may induce systemic side effects. However, RU58841, on topical application, revealed a potent increase in density, thickening, and length of hair in the macaque model of androgenetic alopecia, whereas no systemic effects were detected. Together our results suggest that RU58841 may have potent antagonism to the wt AR (wild type androgen receptor) and could be considered as a topically applied active anti-androgen for the treatment of androgen-dependent skin disorders, such as acne, androgenetic alopecia, and hirsutism."