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07-23-2012 04:21 AM
#1761
Originally Posted by yeahyeahyeah
I think 2020 shouldnt get HSC when it comes out.
I don't know what's happened to 2020. He's gone all crazy recently.
He used to bring up very good info on mechanisms of baldness and whatnot. Now he's just downtalking histogen.
HSC it's better than we all thought to be. The question is if it'll work on everyone !
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07-23-2012 04:39 AM
#1762
2020 if baldness is your main concern with becoming a steroid pumped superman then surely you should be on other forums that are all awaiting cures for the dozen other side effects associated with steroid use, namely liver tumours and heart attacks.
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07-23-2012 04:41 AM
#1763
Talking about Histogen... when is Spencer going to have another interview with Gail? It's been over 2 years...
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07-23-2012 04:59 AM
#1764
Do you think Spencer could ask one of the researchers from one of the major companies their opinion on combining solutions from different companies in a separate clinical trial?
Lets say Histogen combine solutions with Replicel and conduct a phase I trial in say 20 patients?... the research for both solutions is there, we have mountains of it from over 30 years.
Would this be possible? I know they are competitors but perhaps merging they could actually come up with a treatment better than every other company in trials today, it would also work wonders for them financially.
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07-23-2012 09:52 AM
#1765
Senior Member
Originally Posted by Maradona
I don't know what's happened to 2020. He's gone all crazy recently.
He used to bring up very good info on mechanisms of baldness and whatnot. Now he's just downtalking histogen.
not crazy. just the more I research, the more disappointed I become in those future treatments...
Originally Posted by Maradona
HSC it's better than we all thought to be. The question is if it'll work on everyone !
if it works the way I described in previous posts then no. Bald spots will fail to respond to "growth factors" just like they fail to respond to your body's own growth factors due to upregulated COX-2 enzyme.
Is it a coincidence that strong anti-inflammatories, botox, and thymosin grow hair like crazy?
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07-23-2012 10:06 AM
#1766
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07-23-2012 10:10 AM
#1767
Originally Posted by 2020
if it works the way I described in previous posts then no. Bald spots will fail to respond to "growth factors" just like they fail to respond to your body's own growth factors due to upregulated COX-2 enzyme.
Is it a coincidence that strong anti-inflammatories, botox, and thymosin grow hair like crazy?
You have been reading far too many Iron_Man posts.
2 years ago he said wnt ligands would have no impact on hair growth but he was talking rubbish - over that time Histogen have proved him wrong and wnt proteins have also reversed grey hair.
A regular NSAID can be used as a COX-2 inhibitor, you can try celecoxib (Celebrex), valdecoxib (Bextra), parecoxib (Dynastat), lumiracoxib - to see if it brings you back to NW1 but I doubt it will.
(Although I believe some were taken off the market because Merck fabricated some of the clinical trials' data surrounding the analgesic effects of the drugs - leading many to encounter fatal cardiovascular complications, some of the products were taken off the market.
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07-23-2012 10:20 AM
#1768
Originally Posted by 2020
not crazy. just the more I research, the more disappointed I become in those future treatments...
if it works the way I described in previous posts then no. Bald spots will fail to respond to "growth factors" just like they fail to respond to your body's own growth factors due to upregulated COX-2 enzyme.
Is it a coincidence that strong anti-inflammatories, botox, and thymosin grow hair like crazy?
Maybe you should leave this to the professionals.
Your research at best is novice.
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07-23-2012 10:26 AM
#1769
Senior Member
Originally Posted by UK_
"Rejuvenate and repair hair follicle".... sighs... the follicle is fine. Leave follicles alone
Originally Posted by UK_
You have been reading far too many Iron_Man posts.
2 years ago he said wnt ligands would have no impact on hair growth but he was talking rubbish - over that time Histogen have proved him wrong and wnt proteins have also reversed grey hair.
right but they didn't make any injections into bald spots where inflammation is upregulated the most.
Also another question: how long will these results last? What makes them think that your body will take over once these growth factors "wear off"?
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07-23-2012 10:36 AM
#1770
Lol they have lasted past the two year mark - how do you know that the results have declined? Maybe Gail Naughton will come on the show and say "yes the first patients are still experiencing stable hair growth" - what will you say then?
And plz name me another treatment that you use ONCE and then experience hair growth for 2 years?
Can you and Iron_Man please find me a COX-2 inhibitor that can do that?
I doubt it.
Regarding your comments about "the HSC not used in bald spots" - in all honesty, some of the pictures at baseline, the hair looked pretty shit to me - you could see copious amounts of vellus hair that looked like they had endured years of being raped by DHT - and all of a sudden 6 months later they were glowing terminal hairs and had new hairs surrounding them. I call that a win.
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