Replicel

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  • UK_
    Senior Member
    • Feb 2011
    • 2744

    Id love to see Replicel and HSC injected together and then 6 month results.

    Comment

    • Kiwi
      Senior Member
      • Mar 2011
      • 1105

      Originally posted by nikemata
      What is replicel?
      5,6, 7 years away?

      Comment

      • 2020
        Senior Member
        • Jan 2012
        • 1527

        UK, my point is that you don't need to grow anything.... everything is already there but for some reason refuse to grow. Follicles shrink and enlarge themselves automatically due to your body's own natural growth factors.

        HSC may be able to emulate what stem cells are doing, but what's the point if it will last two years or so since stem cells still refuse to work like that automatically

        Comment

        • Pate
          Senior Member
          • Sep 2011
          • 427

          Originally posted by UK_
          Im not saying they did say they outright created new follicles - Gail Naughton stated she BELIEVED HSC was creating new follicles from stem cells already in the scalp. Dr Ziering also stated he believed HSC may be reactivating the dormant hair follicles that still retain their original stem cells but are not producing the needed progenitor cells. Now im not saying his word is gospel, im not saying anyones word is gospel, I just choose to prefer the opinions of people who know what they're talking about as opposed to negative naysayers who should be on HairSite.

          Before 2011, did you even know that bald scalps retain their stem cells? Did anyone on here know that? NO... so why should I believe the negative opinions of the people on here regarding Histogen?

          I dont deny that they have not proved they can grow new follicles in vivo, nobody is saying they can - I only mentioned a difference in hair count, but you cant stipulate with 100% certainty that there were no new follicles created just like I cant stipulate with 100% certainty that new follicles WERE created - that's my only point.
          No, we can't be sure they haven't created new follicles. But whether they have or haven't it's pretty obviously not the main reason for increased hair count, because the areas tested were not missing follicles in the first place.

          2020 said: "so far Histogen was only able to grow BRAND NEW FOLLICLES in VITRO... from the past two studies they still weren't able to confirm if HSC did in fact grow any new follicles."

          You said: "So how do you explain the difference in hair count from baseline to 12 weeks in BOTH studies? "

          Simple: revitalised follicles = longer anagen = more hairs growing at any one time = increased hair count.

          Anyway, sounds like we are in agreement now that that has been clarified.

          Hurry up Histogen. Give us some more results to argue about.

          Comment

          • Conpecia
            Senior Member
            • Sep 2011
            • 911

            Pate, when you say the areas tested were not missing follicles, does that mean the areas were not "balding" areas to begin with? Or is that to say that the follicles were merely dormant in balding areas and were revitalized?

            Comment

            • Kiwi
              Senior Member
              • Mar 2011
              • 1105

              Originally posted by Conpecia
              Pate, when you say the areas tested were not missing follicles, does that mean the areas were not "balding" areas to begin with? Or is that to say that the follicles were merely dormant in balding areas and were revitalized?
              Pâté doesn't work for Histogen and isn't a scientist. And therefore has no ****ing clue what the truth is.

              Comment

              • UK_
                Senior Member
                • Feb 2011
                • 2744

                Originally posted by Pate
                No, we can't be sure they haven't created new follicles. But whether they have or haven't it's pretty obviously not the main reason for increased hair count, because the areas tested were not missing follicles in the first place.

                2020 said: "so far Histogen was only able to grow BRAND NEW FOLLICLES in VITRO... from the past two studies they still weren't able to confirm if HSC did in fact grow any new follicles."

                You said: "So how do you explain the difference in hair count from baseline to 12 weeks in BOTH studies? "

                Simple: revitalised follicles = longer anagen = more hairs growing at any one time = increased hair count.

                Anyway, sounds like we are in agreement now that that has been clarified.

                Hurry up Histogen. Give us some more results to argue about.

                I did indeed question why there was a higher hair count, but I did not offer an absolute conclusion, it would be silly for me to stipulate with 100% certainty that new follicles were the reason for the higher hair count, but the hair count continued to increase right up to 12 months.

                Now you can explain this by saying more follicles were simply revitalised in that period, but you can't outright deny the possibility of HSC inducing the growth of new hair follicles, can you? Yes/No?

                My entire point to you & 2020 is that you MUST recognise the probability that new hair follicles were created during the two trials, especially given that the actual scientists who actually conducted the research do BELIEVE new hair follicles grew.

                Comment

                • UK_
                  Senior Member
                  • Feb 2011
                  • 2744

                  Pate, I dont understand your comment about "the fear of HSC creating new follicles due to density of follicles in the scalp".

                  Do you have the same fear for companies like Aderans and Replicel?

                  Comment

                  • neversaynever
                    Senior Member
                    • Dec 2011
                    • 648

                    Originally posted by 2020
                    UK, my point is that you don't need to grow anything.... everything is already there but for some reason refuse to grow. Follicles shrink and enlarge themselves automatically due to your body's own natural growth factors.

                    HSC may be able to emulate what stem cells are doing, but what's the point if it will last two years or so since stem cells still refuse to work like that automatically
                    Ill take two years of hair, please!

                    Comment

                    • neversaynever
                      Senior Member
                      • Dec 2011
                      • 648

                      Originally posted by UK_
                      Id love to see Replicel and HSC injected together and then 6 month results.
                      100000% agree.

                      Comment

                      • neversaynever
                        Senior Member
                        • Dec 2011
                        • 648

                        Im excited about HSC. But I must say, the results theyve made public so far are still very vague. Not that its important what we think, given their priority right now is investment.

                        Not long before we know more.

                        Comment

                        • 2020
                          Senior Member
                          • Jan 2012
                          • 1527

                          Originally posted by neversaynever
                          Ill take two years of hair, please!
                          you people still don't get it.... eventually you will be a NW6 right? The rest of the hair will start thinning too right? How are you planning to keep up with the CYCLING? not talking about density, I'm talking about CYCLING.

                          If you want some temporary hair there already are compounds that can regrow you that and that's my point - why do all this research if this is just another "boost" and not an actual reversal of a condition? Why go through all those clinical phases? I understand why Replicel and Aderans have to go but in the case of Histogen I don't. They're either wasting time or hiding something from us

                          Comment

                          • Maradona
                            Senior Member
                            • Nov 2011
                            • 830

                            Originally posted by 2020
                            you people still don't get it.... eventually you will be a NW6 right? The rest of the hair will start thinning too right? How are you planning to keep up with the CYCLING? not talking about density, I'm talking about CYCLING.

                            If you want some temporary hair there already are compounds that can regrow you that and that's my point - why do all this research if this is just another "boost" and not an actual reversal of a condition? Why go through all those clinical phases? I understand why Replicel and Aderans have to go but in the case of Histogen I don't. They're either wasting time or hiding something from us
                            we all get it, 2020. I'll take 2 years too. We are not gonna live forever you know? Hopefully I can use histogen until my mid 30s then **** it, razor time !!!!!!!!

                            Comment

                            • 2020
                              Senior Member
                              • Jan 2012
                              • 1527

                              Originally posted by Maradona
                              we all get it, 2020. I'll take 2 years too. We are not gonna live forever you know? Hopefully I can use histogen until my mid 30s then **** it, razor time !!!!!!!!
                              not my point. If it's true that HSC results are temporary and they're not actually reversing MPB then they're wasting time and money. Temporary COSMETIC improvements don't need to go through those FDA phases I don't know why they're doing that then.
                              You want temporary hair? There you go:


                              Hello -- Have any of you used peps and experienced hair growth where before you were thinning/receding? Any experiences using PAL-GHK? or are there any other peptides shown to increase hair growth? Thank you for your feedback.


                              why wait for Histogen then?

                              Comment

                              • yeahyeahyeah
                                Senior Member
                                • Nov 2011
                                • 1818

                                Originally posted by 2020
                                you people still don't get it.... eventually you will be a NW6 right? The rest of the hair will start thinning too right? How are you planning to keep up with the CYCLING? not talking about density, I'm talking about CYCLING.

                                If you want some temporary hair there already are compounds that can regrow you that and that's my point - why do all this research if this is just another "boost" and not an actual reversal of a condition? Why go through all those clinical phases? I understand why Replicel and Aderans have to go but in the case of Histogen I don't. They're either wasting time or hiding something from us
                                Why dont you let them get on with it, rather then speculate.

                                Comment

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