-
05-30-2012 05:48 AM
#1991
Latanoprost is an older drug than bimatoprost, in fact the patent has already expired so it's available generic.
Latanoprost is also, I believe, the drug that was tested on macaque monkeys with MPB, some years ago now.
It's one of those drugs that's been around for years and but never made it on to the market for MPB, presumably because of the belief its effectiveness is limited and it would cost too much to get it through trials.
One of the depressing, constant themes of hair loss drug development. So many drugs offer more potential than minox or fin but are never developed for commercial reasons, so we're stuck with those two dinosaurs.
Hopefully the bimatoprost results are positive and Allergan rush to Phase III, knowing they will have Histogen breathing down their necks. I personally believe bimatoprost is the only new treatment we've got a chance of seeing this side of 2015.
-
05-30-2012 11:58 AM
#1992
Originally Posted by Pate
so we're stuck with those two dinosaurs.
Lol yeh an one of them's a T-Rex that'll bite off yr dick if you're lucky enough.
I always thought Bimatoprost works in the same way as Minox - does it force hairs to shed initially like minox?
-
05-30-2012 12:01 PM
#1993
Hey UK how's the Minox going? Been on it some time now, if still using it?
-
05-31-2012 05:21 AM
#1994
Pate, Good Info. I guess I didn't read the article closely enough as I assumed the clinical trial was conducted by Allergan but their clinical trial is with Bimatoprost. I agree that this looks like next most likely advance to reach the market
Here is small bit of research supporting that perspective:
http://dermatology-s10.cdlib.org/93/...ecia/wolf.html
"Even though scalp hair follicles and eyelash follicles are not identical, and one cannot simply extrapolate from a drug's effect on one type of hair to another, we believe that a powerful hair stimulant that acts on one type of hair should act on other types as well. Several of the above-mentioned experimental studies support the stimulating effects of PG analogs on hairs other than eyelashes (i.e., scalp hair and body fur). Furthermore, if the proposed mechanism of minoxidil action is indeed through its stimulating effect of PGE2 synthesis, then one should ask why we need to stimulate the synthesis of PG if we can use it directly? Minoxidil (which has been used by women to thicken their eyelashes and to treat alopecia areata of this area) showed inferior results on eyelash growth than those described for latanoprost. Minoxidil and finasteride must be used continuously to sustain results, and, once discontinued, the natural balding process resumes. PG analogs have a much more powerful and longer-lasting effect.[18]"
Also, it appears that Bimatoprost may be more effective than Latanoprost with respect to hair growth...there was actually a study comparing the two:
http://clinicaltrials.gov/ct2/show/NCT00187577 (Comparison of Latanoprost vs Bimatoprost re eyelash growth)
Not sure if this refers to the same study but sounds like there might be quite a difference:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861943/
"In a 3-month bimatoprost versus latanoprost trial, eyelash growth was more common in the bimatoprost group (13% bimatoprost vs. 4% latanoprost)"
-
05-31-2012 06:34 AM
#1995
Senior Member
Best news I heard all week. Thanks for sharing.
-
05-31-2012 06:56 AM
#1996
Hmm, is it possible that Bim for hair loss would be so powerful that we wouldn't need to use Fin with it? I. e. would it be able to maintain hair for a very long time? And what year is it expected to hit the market?
-
05-31-2012 07:02 AM
#1997
Originally Posted by PinotQ
Pate, Good Info. I guess I didn't read the article closely enough as I assumed the clinical trial was conducted by Allergan but their clinical trial is with Bimatoprost. I agree that this looks like next most likely advance to reach the market
Here is small bit of research supporting that perspective:
http://dermatology-s10.cdlib.org/93/...ecia/wolf.html
"Even though scalp hair follicles and eyelash follicles are not identical, and one cannot simply extrapolate from a drug's effect on one type of hair to another, we believe that a powerful hair stimulant that acts on one type of hair should act on other types as well. Several of the above-mentioned experimental studies support the stimulating effects of PG analogs on hairs other than eyelashes (i.e., scalp hair and body fur). Furthermore, if the proposed mechanism of minoxidil action is indeed through its stimulating effect of PGE2 synthesis, then one should ask why we need to stimulate the synthesis of PG if we can use it directly? Minoxidil (which has been used by women to thicken their eyelashes and to treat alopecia areata of this area) showed inferior results on eyelash growth than those described for latanoprost. Minoxidil and finasteride must be used continuously to sustain results, and, once discontinued, the natural balding process resumes. PG analogs have a much more powerful and longer-lasting effect.[18]"
Also, it appears that Bimatoprost may be more effective than Latanoprost with respect to hair growth...there was actually a study comparing the two:
http://clinicaltrials.gov/ct2/show/NCT00187577 (Comparison of Latanoprost vs Bimatoprost re eyelash growth)
Not sure if this refers to the same study but sounds like there might be quite a difference:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861943/
"In a 3-month bimatoprost versus latanoprost trial, eyelash growth was more common in the bimatoprost group (13% bimatoprost vs. 4% latanoprost)"
Does this mean that we don't have to use this permanently.
The other thing is:
We can get bitmoprost online, why not experiment with that?
-
05-31-2012 07:11 AM
#1998
This stuff is expensive like hell. 2000$ for a gram!! 3ml bottle of Latisse 0.03% costs around 100$. If you were to apply it on the whole head, it would last 1 day! I hope when they'll reach the mass market, the price for the ready product will be considerably lower.
-
05-31-2012 07:26 AM
#1999
Senior Member
Originally Posted by TravisB
This stuff is expensive like hell. 2000$ for a gram!! 3ml bottle of Latisse 0.03% costs around 100$. If you were to apply it on the whole head, it would last 1 day! I hope when they'll reach the mass market, the price for the ready product will be considerably lower.
Latisse is not marketable to people with MPB at that price, and they know it. Especially considering that you can currently buy it at that price, and almost no one with MPB is. The going theory is that they will change production scale and lower the price to as much as they think people will pay for it, which is probably true. That's how the free market typically works.
-
05-31-2012 07:43 AM
#2000
Originally Posted by Davey Jones
Latisse is not marketable to people with MPB at that price, and they know it. Especially considering that you can currently buy it at that price, and almost no one with MPB is. The going theory is that they will change production scale and lower the price to as much as they think people will pay for it, which is probably true. That's how the free market typically works.
The problem is, what is stopping people who use for their eye lashes to buy the MPB version - given it is cheaper?
Similar Threads
-
By tbtadmin in forum Histogen's Hair Stimulating Complex (HSC)
Replies: 5
Last Post: 07-21-2016, 01:34 PM
-
By tbtadmin in forum Men's Hair Loss: Start Your Own Topic
Replies: 14
Last Post: 05-09-2011, 03:06 AM
-
By tbtadmin in forum The Bald Truth: Show Archives
Replies: 2
Last Post: 11-04-2010, 09:10 PM
-
By tbtadmin in forum The Bald Truth: Show Archives
Replies: 0
Last Post: 08-17-2010, 01:01 PM
Tags for this Thread
Posting Permissions
- You may not post new threads
- You may not post replies
- You may not post attachments
- You may not edit your posts
Forum Rules
|
» IAHRS
» The Bald Truth
» americanhairloss.org
|
Bookmarks