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Old 04-29-2012, 10:09 AM   #1351
The Alchemist
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There are a couple things that I haven't heard discussed here.

First, this was a safety "overdosing" trial. Is it possible that the injection of millions of cells-in excess of Replicel thinks is necessary or would actually be used in treatement, actually had a negative effect upon the result. Sometimes, with certain treatments, as the dosage increases, there is a point where if go further with additional dosage, that the beneficial result actually reverses and could potentially go to the negative. Sometimes, more is not better.

Second, because this is a safety trial first, the worst outcome would be if someone ended up getting sick or ill as a result of the treatement. So, there is a possibility that since the initial announcement that no patient was showing any ill effect that someone did show some negative effect. In fact, they could have positive hair growth in most patients but someone showed some illness as a result, providing a good/bad outcome.

All good points!
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Old 04-29-2012, 10:34 AM   #1352
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i thought that too, shouldnt this trial show if it's safe GIVEN THAT it's already positive and grows hair?
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Old 04-29-2012, 10:52 AM   #1353
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Originally Posted by Johny.track131 View Post
i thought that too, shouldnt this trial show if it's safe GIVEN THAT it's already positive and grows hair?
Well, no. Phase I is about safety; Phase II is about efficacy. The protocol is to demonstrate the treatment to be safe, then demonstrate it to be effective.
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Old 04-29-2012, 11:32 AM   #1354
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Well Phase 1 grew hair so give me that dosage and inject it into my fecking head.

Even if thats all it can achieve its better than nothing.
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Old 04-29-2012, 11:40 AM   #1355
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Well Phase 1 grew hair so give me that dosage and inject it into my fecking head.
The results of Replicel's Phase I/IIa trial haven't been released yet, so how could you know that "Phase 1 grew hair"?
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Old 04-29-2012, 12:08 PM   #1356
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How many times have you refreshed the Replicel main page in the past 24 hours?
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Old 04-29-2012, 12:09 PM   #1357
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Well Phase 1 grew hair so give me that dosage and inject it into my fecking head.

Even if thats all it can achieve its better than nothing.
Phase 1?... You mean the "it worked on mice" phase?
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Old 04-29-2012, 12:20 PM   #1358
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Phase 1?... You mean the "it worked on mice" phase?
Yepp, Glue about 6 dead mice to my head. Sorted.

Oh for feck sake. Which potential baldness cure grew hair, there were photos of it, albeit very very minimal results I guess that was Histogen?
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Old 04-29-2012, 12:24 PM   #1359
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Yepp, Glue about 6 dead mice to my head. Sorted.

Oh for feck sake. Which potential baldness cure grew hair, there were photos of it, albeit very very minimal results I guess that was Histogen?
Are you referring to.... SAW PALMETTO?
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Old 04-29-2012, 12:32 PM   #1360
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So.. monday, I guess?
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