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04-29-2012, 10:09 AM
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#1351
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Senior Member
Join Date: Mar 2011
Posts: 187
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Quote:
Originally Posted by lpenergy
There are a couple things that I haven't heard discussed here.
First, this was a safety "overdosing" trial. Is it possible that the injection of millions of cells-in excess of Replicel thinks is necessary or would actually be used in treatement, actually had a negative effect upon the result. Sometimes, with certain treatments, as the dosage increases, there is a point where if go further with additional dosage, that the beneficial result actually reverses and could potentially go to the negative. Sometimes, more is not better.
Second, because this is a safety trial first, the worst outcome would be if someone ended up getting sick or ill as a result of the treatement. So, there is a possibility that since the initial announcement that no patient was showing any ill effect that someone did show some negative effect. In fact, they could have positive hair growth in most patients but someone showed some illness as a result, providing a good/bad outcome.
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All good points!
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04-29-2012, 10:34 AM
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#1352
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Member
Join Date: Feb 2012
Posts: 96
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i thought that too, shouldnt this trial show if it's safe GIVEN THAT it's already positive and grows hair?
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04-29-2012, 10:52 AM
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#1353
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Senior Member
Join Date: Apr 2010
Location: Los Angeles, California
Posts: 896
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Quote:
Originally Posted by Johny.track131
i thought that too, shouldnt this trial show if it's safe GIVEN THAT it's already positive and grows hair?
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Well, no. Phase I is about safety; Phase II is about efficacy. The protocol is to demonstrate the treatment to be safe, then demonstrate it to be effective.
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04-29-2012, 11:32 AM
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#1354
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Senior Member
Join Date: Jan 2012
Posts: 661
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Well Phase 1 grew hair so give me that dosage and inject it into my fecking head.
Even if thats all it can achieve its better than nothing.
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04-29-2012, 11:40 AM
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#1355
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Senior Member
Join Date: Apr 2010
Location: Los Angeles, California
Posts: 896
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Quote:
Originally Posted by sausage
Well Phase 1 grew hair so give me that dosage and inject it into my fecking head.
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The results of Replicel's Phase I/IIa trial haven't been released yet, so how could you know that "Phase 1 grew hair"?
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04-29-2012, 12:08 PM
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#1356
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Senior Member
Join Date: Feb 2011
Posts: 1,984
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 How many times have you refreshed the Replicel main page in the past 24 hours?
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04-29-2012, 12:09 PM
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#1357
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Senior Member
Join Date: Feb 2011
Posts: 1,984
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Quote:
Originally Posted by sausage
Well Phase 1 grew hair so give me that dosage and inject it into my fecking head.
Even if thats all it can achieve its better than nothing.
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Phase 1?... You mean the "it worked on mice" phase?
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04-29-2012, 12:20 PM
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#1358
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Senior Member
Join Date: Jan 2012
Posts: 661
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Quote:
Originally Posted by UK_
Phase 1?... You mean the "it worked on mice" phase? 
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Yepp, Glue about 6 dead mice to my head. Sorted.
Oh for feck sake. Which potential baldness cure grew hair, there were photos of it, albeit very very minimal results I guess that was Histogen?
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04-29-2012, 12:24 PM
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#1359
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Senior Member
Join Date: Feb 2011
Posts: 1,984
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Quote:
Originally Posted by sausage
Yepp, Glue about 6 dead mice to my head. Sorted.
Oh for feck sake. Which potential baldness cure grew hair, there were photos of it, albeit very very minimal results I guess that was Histogen?
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Are you referring to.... SAW PALMETTO? 
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04-29-2012, 12:32 PM
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#1360
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Senior Member
Join Date: Aug 2011
Posts: 1,342
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So.. monday, I guess?
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