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Old 06-13-2011, 11:58 AM   #631
UK_
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So have they abandoned their "wnt"/gene therapy approach?

If they've failed on their previous approaches then we're all pretty much screwed b/c this lithium treatment doesn't look at all promising.

I really wanna find out what they spoke of at that conference, they must have mentioned something about the trial, good or bad.
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Old 06-13-2011, 12:03 PM   #632
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So have they abandoned their "wnt"/gene therapy approach?
no one rly knows. their research shows that lithium is the wnt modulator that they use. or thats how i understood it. there are some papers around so if youre interested you can read them. lithium + wounding grew most of hair in mice experiments. thats what i remember from one of the papers.
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Old 06-13-2011, 12:11 PM   #633
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Oh right thanks, yeah sorry im a bit lazy to read up on all their latest releases lol.

Thanks for the information though.
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Old 06-13-2011, 02:56 PM   #634
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Default Follica's wounding

Reading through that whole patent thing makes me feel less comfortable with Follica's treatment. I knew they were using wounding but I always thought it would be very superficial. They say it's dermabrasion which I've heard of before and didn't think caused scaring cos people have it done to re-juvinate the skin on their faces. When you read the conditions to be a test subject it mentions that you can't be susceptible to keloid scaring or hyper-pigmentation though and I've always associated these kinds of scaring with full depth wounds like the type you get from a traditional transplant. The whole reason I'm interested in the new generation of treatments is in part due to the fact that they talk about being minimally invasive - no scaring - so if there's gonna be a risk of getting scars all over your scalp with Follica's treatment then I'm gonna count it out anyway.
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Old 06-13-2011, 03:02 PM   #635
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I'd agree with that. Doesn't sound like a runner to me. I'm now wondering if Histogen and Aderans will supplement each other. That's my hope anyway. Also hopefully Aderans compounds. I was initially under the impression that they would inject the cellular 'seeds' so to speak for individual follicles, as in 90 small injections in 1 square centimetre for 90 follicles, but now I'm not so sure that that's what they're doing. The last presentation I saw made it seem quite similiar to HSC albeit using you're own cells.
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Old 06-13-2011, 05:47 PM   #636
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Well the treatment would fail clinical trial if it created scar tissue, so you wouldn't even have the chance to use it. I doubt we can just write it off on the basis of our 'clinical knowledge'.

Follica are a highly secretive company, I doubt anyone could even come close to mimicking the process they have spent all this time working on, I do believe they have something.
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Old 06-13-2011, 07:34 PM   #637
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Well the treatment would fail clinical trial if it created scar tissue, so you wouldn't even have the chance to use it. I doubt we can just write it off on the basis of our 'clinical knowledge'.

Follica are a highly secretive company, I doubt anyone could even come close to mimicking the process they have spent all this time working on, I do believe they have something.
Have they given us any type of time frame at all? I know histogen and aderans say 2014-15 (but who knows with them...)
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Old 06-13-2011, 07:44 PM   #638
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Have they given us any type of time frame at all? I know histogen and aderans say 2014-15 (but who knows with them...)
Not too sure on that one, God knows when/if they will make public the results of their Phase II.
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Old 06-13-2011, 08:25 PM   #639
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Not too sure on that one, God knows when/if they will make public the results of their Phase II.
Oh alright. And are they doing phase II now? Sorry I'm not completely up to date on all of these companies
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Old 06-13-2011, 11:18 PM   #640
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Well the treatment would fail clinical trial if it created scar tissue, so you wouldn't even have the chance to use it. I doubt we can just write it off on the basis of our 'clinical knowledge'.

Follica are a highly secretive company, I doubt anyone could even come close to mimicking the process they have spent all this time working on, I do believe they have something.
That's the problem with Follica. They don't say shit, so it's really hard to know anything. They release bits of news and nothing more. I wasn't able to listen to the whole shit but they are using
a compound and according to Joe, they did not want to say what it is, for obvious reasons. Nobody is saying they have the cure, this is just info for the public. It's always good to hear anything that comes out of them, since they stay quiet. We are so used to ****ing promises and companies talking loud but never bring shit. Follica has made some valuable discoveries so we know they are not playing. They might have something like you say but Who knows how close they are to something big.
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