Bald Truth Talk - Hair Loss, Hair Transplant and Hair Restoration Community  

Go Back   Bald Truth Talk - Hair Loss, Hair Transplant and Hair Restoration Community > Men's Hair Loss > Men's Hair Loss: Start Your Own Topic
Register Blogs FAQ Members List Calendar Mark Forums Read

Reply
 
Thread Tools Display Modes
Old 02-13-2013, 05:20 PM   #1
FearTheLoss
Senior Member
 
Join Date: Dec 2012
Posts: 929
Default GLA for hair loss

2020 posted that GLA helps maintain hair loss.. What is GLA and where can I get it?
FearTheLoss is offline   Reply With Quote
Old 02-13-2013, 06:33 PM   #2
2020
Senior Member
 
2020's Avatar
 
Join Date: Jan 2012
Posts: 1,527
Default

Quote:
Originally Posted by FearTheLoss View Post
2020 posted that GLA helps maintain hair loss.. What is GLA and where can I get it?
http://en.wikipedia.org/wiki/Gamma-Linolenic_acid

It's still a "DHT blocker" but it's supposed to be dose dependent plus it should work in other pathways thus it should be much more safe.


Study proving that it does block DHT:
http://www.ncbi.nlm.nih.gov/pubmed/7735002

It also supresses inflammation COX-2, LOX (PGD2?) and increases PGE1(good thing, another study)
http://www.ncbi.nlm.nih.gov/pubmed/15197770



Treatment of male pattern baldness and of unwanted hair growth.
http://www.freepatentsonline.com/EP0309086.html

Quote:
In a test of the effectiveness of the invention, four middle-aged males with rapidly progressing baldness were treated orally with either 6g of evening primrose oil or 6g of a mixture of evening primrose oil and concentrated fish oil (20%) per day. The primrose oil provided approximately 90mg of 18:3n-6 (gamma-linolenic acid, GLA) per gram and the fish oil 180mg of 20:5n-3 (eicosapentaenoic acid, EPA) and 120mg of docosahexaenoic acid (DHA) per gram. After delays of 4 to 8 weeks, all four individuals reported unequivocal hair growth, with extension of hair growth to previously bald areas of the scalp, and a strengthening of growth in those areas where hair was present but thinning. Topical application of the unsaturated fatty acids provides better results by increasing the concentration of the fatty acid at the hair follicle level.

In further tests, one male applied pure evening primrose oil twice per day to half the beard area. After about two weeks, the rate of beard growth on the side of the face to which the oil had been applied was definitely less than on the other side. Similarly, one female shaved both legs and then applied evening primrose oil twice daily to one leg only. After a period of 6-8 weeks it could be seen that the rate of hair growth was substantially less on the leg to which the oil had been applied.

These preliminary tests indicate that both oral and topical application of unsaturated fatty acids is able to modulate the actions of androgens on the hair follicles, stimulating hair growth on the scalp and reducing it on other areas of the body.
I personally haven't tried it yet but will so soon...
2020 is offline   Reply With Quote
Old 02-13-2013, 06:39 PM   #3
FearTheLoss
Senior Member
 
Join Date: Dec 2012
Posts: 929
Default

Quote:
Originally Posted by 2020 View Post
http://en.wikipedia.org/wiki/Gamma-Linolenic_acid

It's still a "DHT blocker" but it's supposed to be dose dependent plus it should work in other pathways thus it should be much more safe.


Study proving that it does block DHT:
http://www.ncbi.nlm.nih.gov/pubmed/7735002

It also supresses inflammation COX-2, LOX (PGD2?) and increases PGE1(good thing, another study)
http://www.ncbi.nlm.nih.gov/pubmed/15197770


Treatment of male pattern baldness and of unwanted hair growth.
http://www.freepatentsonline.com/EP0309086.html



I personally haven't tried it yet but will so soon...

Seems legit...how would I get this? and do you think this is going to be commercialized?
FearTheLoss is offline   Reply With Quote
Old 02-13-2013, 06:56 PM   #4
2020
Senior Member
 
2020's Avatar
 
Join Date: Jan 2012
Posts: 1,527
Default

Quote:
Originally Posted by FearTheLoss View Post
Seems legit...how would I get this? and do you think this is going to be commercialized?
??? GLA is a simple fatty acid available virtually everywhere. This isn't anything new.

http://www.amazon.com/s/field-keywords=gla
> 16,000 results
2020 is offline   Reply With Quote
Old 02-13-2013, 07:23 PM   #5
FearTheLoss
Senior Member
 
Join Date: Dec 2012
Posts: 929
Default

Quote:
Originally Posted by 2020 View Post
??? GLA is a simple fatty acid available virtually everywhere. This isn't anything new.

http://www.amazon.com/s/field-keywords=gla
> 16,000 results
and you are saying this works in pill form? just take one a day? the studies say it's been tried as a topical but how would you make this a topical?
FearTheLoss is offline   Reply With Quote
Old 02-13-2013, 07:28 PM   #6
2020
Senior Member
 
2020's Avatar
 
Join Date: Jan 2012
Posts: 1,527
Default

Quote:
Originally Posted by FearTheLoss View Post
and you are saying this works in pill form? just take one a day? the studies say it's been tried as a topical but how would you make this a topical?
...

"...four middle-aged males with rapidly progressing baldness were treated orally..."

yes, why wouldn't it work? It just says that it might provide better results topically. Finasteride works orally too and likely would provide some results topically as well...
2020 is offline   Reply With Quote
Old 02-13-2013, 07:32 PM   #7
FearTheLoss
Senior Member
 
Join Date: Dec 2012
Posts: 929
Default

Quote:
Originally Posted by 2020 View Post
...

"...four middle-aged males with rapidly progressing baldness were treated orally..."

yes, why wouldn't it work? It just says that it might provide better results topically. Finasteride works orally too and likely would provide some results topically as well...
Alright I think I may try this? Are you going to start? just wondering why no one else has talked about this..
FearTheLoss is offline   Reply With Quote
Old 02-13-2013, 07:44 PM   #8
FearTheLoss
Senior Member
 
Join Date: Dec 2012
Posts: 929
Default

I just did some reading on this and you need GLA in free form, its pure form to work as a 5a-inhibitor...so these pills in the link won't work, if what I read was correct.
FearTheLoss is offline   Reply With Quote
Old 02-13-2013, 07:54 PM   #9
2020
Senior Member
 
2020's Avatar
 
Join Date: Jan 2012
Posts: 1,527
Default

Everything works in any form there is no such thing and this has been discussed plenty. I started this thread last year on HLT:
http://www.hairlosstalk.com/interact...ults-from-1988!
2020 is offline   Reply With Quote
Old 02-13-2013, 08:01 PM   #10
FearTheLoss
Senior Member
 
Join Date: Dec 2012
Posts: 929
Default

Androgen action in many organs, such as prostate and skin, is dependent on the conversion of testosterone by 5 alpha-reductase to 5 alpha-dihydrotestosterone. 5 alpha-Dihydrotestosterone then binds to the androgen receptor to regulate specific gene expression. Inhibitors of 5 alpha-reductase are useful for the selective treatment of prostatic cancer, benign prostate hyperplasia, acne, baldness and female hirsutism, without affecting spermatogenesis, sexual behavior and smooth muscle growth, that do not require the conversion of testosterone to 5 alpha-dihydrotestosterone. Certain unsaturated fatty acids, such as gamma-linolenic acid, are potent 5 alpha-reductase inhibitors, suggesting a linkage between unsaturated fatty acids and androgen action. Mutations in androgen receptor genes are responsible for many cases of androgen-insensitivity. In some prostate cancer cells, some antiandrogens may act like androgens in stimulating the proliferation of the cancer cells because these antiandrogens can bind to a mutated androgen receptor and transactivate target genes. Prostate cancers are usually androgen-dependent initially but can lose dependency and responsiveness. Tumor cells which are resistant to endocrine therapy ultimately proliferate. Androgen-independent or androgen-repressive cells can arise from androgen-sensitive prostate cancer cells by changes in specific gene expression over time in a clonal isolate. This change in androgen responsiveness was accompanied by a change in androgen receptor expression and transcriptional activity as well as expression of some oncogenes.

Studies Gamma Linolenic Acid, Alpha Linolenic Acid, and Linoleic Acid
In the following studies, Gamma Linolenic Acid (GLA), Alpha Linolenic Acid (ALA), and Linoleic Acid were shown to be the most potent known inhibitors of type 1 and 2 forms of 5-alpha reductase and highly effective in decreasing the levels of dihydrotestosterone (DHT). More importantly this is accomplished without affecting any systemic effects. The study further suggests that these fatty acids can be useful in the treatment of disorders related to dihydrotestosterone including male pattern baldness, acne, and excessive female body hair (hirsuitism).


So we need Borage oil+ Omega 3 fish oil with a lot of EPA DHA along with Sesamin oil internally= bad ass hairloss treatment.
FearTheLoss is offline   Reply With Quote
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Crash Diet, weight loss and Hair loss and itchiness beeswaxtnt Introduce Yourself & Share Your Story 4 02-22-2014 01:59 PM
MatriStem® Micro Matrix - Hair Loss Breakthrough or Hair Loss Hype? Updated Commentar tbtadmin The Bald Truth: Show Archives 0 01-14-2010 04:20 PM
Hair Loss Video Q&A | Have Your Questions Answered by American Hair Loss Association tbtadmin The Bald Truth: Show Archives 0 08-06-2009 06:40 PM
Dealing With Hair Loss and My Concerns For The Future | Mike?s Hair Loss Story tbtadmin The Bald Truth: Show Archives 0 11-21-2008 12:41 PM
Hair Loss Since 14 Years Old - Am I Taking The Right Course of Hair Loss Treatments? tbtadmin IAHRS Info Center Discussion 0 10-29-2008 02:18 PM

» The Bald Truth
» Recent Threads
Stay with fin or switch to dut
03-15-2014 10:04 AM
by Plan C
Last post by thinninghair
Yesterday 10:36 PM
[HELP - PHOTOS ATTACHED] What treatment should I use?
02-10-2014 01:27 AM
Last post by thinninghair
Yesterday 09:32 PM
» Newest Videos

Update On Hairloss 8/10/09...
My hair loss was getting worse, so I just got it cut really short now. I don't think it looks that b...


Hair Loss Remedy Myths Perpetuated Onlin...
We are sure these people mean well, but this is a prime example of why the snake oil industry thrive...


Hair Transplant | "SurgeonofNalts&q...
http://www.baldtruthtalk.comFounder of The American Hair Loss Association Spencer Kobren speaks with...


How Hair Loss Colors Our Lives | Spencer...
...


All times are GMT -7. The time now is 03:09 AM.