KÉRATENE Alphactive ® Retard

[yeahyeahyeah]

Below is the text from the KERATENE website



KÉRATENE® alphactive Retard is a systemic 5-ard enzyme catalyze inhibitor, formulated specifically to suppress the formation of dihydrotestosterone (DHT) and delay the effects of this androgen on the genetically-marked hair follicles, sensitive to its chemical signals. KÉRATENE® alphactive Retard provides an appropriate control mechanism for the progressive thinning of hair caused by hormonal and genetic factors, with potential applications in the trichologic field for the for the maintenance of the existing hair density, in both pre- and postoperative cases.
KÉRATENE® alphactive Retard depresses the total DHT level by suppressing the conversion of the androgen Testosterone (T) to DHT through the adhesion to the 5aRD enzyme by obstructing the transfer of hydrogen atoms to the Testosterone (T) molecule and preventing its chemical reduction.
KÉRATENE® alphactive Retard reduces the DHT levels with a factor of 2, 3 or 4, depending on the total DHT level. KÉRATENE® alphactive Retard does not interfere with the endocrine production of hormones or with the production of the 5aRD enzyme and its inhibition mechanism does not rely on the use of antagonistic exogenic hormone disruptors or on the use of xenoestradiols or estrogens. Consult your doctor before using this product or any other medical anti-DHT treatments. Read the product description carefully before use. KÉRATENE® alphactive Retard is not a cure for any registered medical disease. Consult your doctor for professional medical advice.

KÉRATENE® alphactive Retard, in combination with topical KÉRATENE® alphactive therapies, is suitable as sustaining therapy for the preservation of the trichological density for clinical cases of NW I, NW II, NW III (vertex only), Ludwig I and Ludwig II. This product is not effective in cases of alopecia totalis, alopecia universalis and alopecia androgenetica NW4, NW5 and NW6 as well as Ludwig 3 where total loss of hair density has already occured


- Lowers dht by 25%
- Is fin without side effects/same benefits
- Vouched by pro hair clinic

http://www.hairlossexperiences.com/view_topic.php?id=3278&forum_id=6

Thoughts?

[Tracy C]

Thoughts?

Digesting and looking for legitimate info from outside of hair loss support forums or the company website. None is readily available yet - but will keep looking.

- Is fin without side effects/same benefits...

There is no such thing as a medication that has no side effects. Is is more than likely that any medication that can achieve the same benefits as Finasteride will have a similar side effect profile as Finasteride. Adequate and appropriate studies need to be performed in order to attempt to substantiate this rather lofty claim.

[yeahyeahyeah]

Digesting and looking for legitimate info from outside of hair loss support forums or the company website. None is readily available yet - but will keep looking.





There is no such thing as a medication that has no side effects. Is is more than likely that any medication that can achieve the same benefits as Finasteride will have a similar side effect profile as Finasteride. Adequate and appropriate studies need to be performed in order to attempt to substantiate this rather lofty claim.

Well, from what I have read it works the same way but as of yet, not many have got sides due to it surpressing 25% DHT and not 90% (like fin does)

[yeahyeahyeah]

Hi all,

The company Keratene is not an unknown among hair transplant surgeons and institutes. We have been using their FUE after care treatment kits for a long time.

In September Keratene Presented their new product, Keratene Retard, to the attendees at the annual FUE Europe meeting (this time in Berlin).

They provided solid scientific proof that Keratene Retard is able to reduce DHT blood values. If you are going to present your product that claims DHT lowering properties you better have good solid evidence if you are presenting in front of dermatologist and doctors.
Prohairclinic offered to perform a small additional test to backup the Keratene Retard clinical data.
We teamed up with the university of Gent to measure before and after DHT blood levels.
At half the prescribed dose of 1 capsule a day there was an average lowering of 25 % of DHT levels for male subjects.
There were no changes in DHT levels (slightly up) for female subjects.

More important : there were no side effects reported by any of the candidates. We have yet to receive any side effects from patients that have been taken the product for about 2.5 months now.

I believe this products is a good alternative for those who are unwilling to take medication (Keratene Retard comes as a dietary supplement) or do not want to risk side effects that are associated with Finasteride.

Prohairclinic is an official partner of Keratene and all anti hair loss products are being offered via our webshop:

http://www.prohairclinic.be/

Bart

Some more info.

[yeahyeahyeah]

Some more:

From our experience most people that have sides from finasteride find out within the first couple of weeks.

We have not seen this in any of the test persons. No sides where reported in the recent second study nor in the first study over a year ago.

In fact we have not heared of any side effect to date, not from people using it nor from any of the persons that where involved with the tests.

We have recontacted all of the test patients and some of the people who have bought the product >3 months ago.

Again, nobody reported any side effects, not even the people that had sides when using finasteride.

Of the persons that have been on Keratene for longer then 3 months we had great response. All will continue to use the product, some of then feel that hair quality has already improved. This seems to be resembling response we get from finasteride users.

This will be interesting to follow as we expect an even better response in another 6 months.

B

http://www.hairlossexperiences.com/view_post.php?post_id=29986

[Tracy C]

None of these are outside of parties that have a vested interest in selling the product. This detail contaminates the information they are providing with excessive bias. Will continue to look for more reliable and more credible un-biased information. What I see thus far cannot legitimately substantiate their very lofty claim.

[JimmyJones12]

This sounds too good to be true??

[HARIRI]

Yeah Yeah Yeah, This sounds very interesting. I may use it as a replacement of my saw palmetto supplement (HAIROMEGA DHT). At least it may do something for me as I really cant use FIN because of the sides I got. Thanks for sharing. I will try to look at it more deeply.

Here are more info about it:-

Vegan-friendly : this version is not suitable for Vegan consumers. The gelatin capsules contain animal ingredients obtained according to Kosher / Halal standards
Therapeutical compatibility : not compatible with BPH products based on soy or saw palmetto, Finasteride, Dutasteride, Flutamide of Bicalutamide. Special precautions for users of any ACE (angiotensin-converting-enzyme) inhibitors: consult your doctor before using this product
Side effects : read the enclosed product specific instructions or the online product page. Not suitable during pregnancy or lactation
Sale regime : dietary supplement - OTC
Concentration grade : total DHT reduction factor 2 - 3 - 4
Composition : complex sterols under the DRD of 3gr/24h, plant extracts, saccharose
Active system : 5-ard enzyme catalyse inhibitor
Volume : 60 capsules

[HARIRI]

Here are more information about it from Pro Hair Clinic which I believe endorses the product officially.

KÉRATENE® alphactive retard

Male hair loss is often due to the negative impact of high DHT (Dihydrotestosterone) levels which have a negative influence on the hair roots. This phenomenon is already known for a long time and is often validated by medical research. There exists already certain medication which can decrease the DHT values, however those medicines can lead in some cases to certain unwanted side effects.

ATTENTION: DO NOT COMBINE KÉRATENE® alphactive retard with any of the older DHT decreasing medicines!

KÉRATENE® alphactive retard is a NEW (2012) product which is developed with the latest knowledge and technology. Hence, this product has no side effects and is available without a prescription. KÉRATENE® alphactive retard is categorized as a “ nutritional supplement” this means that it can be freely sold in the EU. In addition, KÉRATENE® alphactive retard has all the necessary authorisations needed for sales in the EU.

KÉRATENE® alphactive retard got its first introduction during the FUE Europe meeting in Berlin 2012. The technical data as well as the results (blood value DHT levels before and after) were presented to all hair transplantation doctors who were present.

Technical information:
formulated specifically to aid in the delaying of the effects of the androgen hormone Dihydrotestosterone (DHT) on the
genetically-marked hair follicles. KÉRATENE® alphactive retard provides a better control of the progressive thinning of
hair caused by hormonal and genetic factors, and it is recommended for the maintenance of the existing hair density,
in both pre- and postoperative cases. KÉRATENE® alphactive retard is sold in some countries under the commercial
name of KE234® or Keratenosynergist®.
Use KÉRATENE® alphactive retard as directed by your doctor or pharmacist.

COMPOSITION:
Sterol complex, phytoextracts, saccharose.
Contains trace amounts of campe- stigma- brassicasterol, triterpenoid esters, 3,4-divanillyltetrahydrofuran and
5-hydroxytryptamine. The formula is free of xenoestradiols and is suitable for both adult men and women.
KÉRATENE® alphactive retard is available in packaging of 30 or 60 gelatine capsules.
Substance regimen: dietary supplement

FUNCTION

KÉRATENE® alphactive retard depresses the total level of DHT by suppressing the conversion of the androgen Testosterone
(T) to DHT through the adhesion to the 5aRD enzyme by obstructing the transfer of hydrogen atoms to the Testosterone
(T) molecule and preventing its chemical reduction.
KÉRATENE® alphactive retard reduces the DHT levels with a factor of 2, 3 or 4, depending on the total DHT level.
KÉRATENE® alphactive retard does not interfere with the endocrine production of hormones or with the production of
the 5aRD enzyme.
The therapy with KÉRATENE® alphactive retard reaches optimal effects after 7 consecutive days of administration.
KÉRATENE® alphactive retard has low bioaccumulation and its effects dissipate after 3 to 7 consecutive days after the
interruption of the therapy. When the therapy is completely terminated, the DHT level will increase and reach its previous
nominal value, prior to the administration.

ADMINISTRATION
KÉRATENE® alphactive retard is administered orally.

Pre- and post-operative schedule, when the DHL level is known:
1) DHT level between 849 and 1673 pg/ml, 1 capsule per day,
in the morning between 8 and 9;
2) DHT level higher than 1673 pg/ml, 2 capsules per day, one capsule in the morning
between 8 and 9 and one capsule in the evening between 10 and 11.
Pre- and post-operative schedule, when the DHL level is not known:
Men older than 20 with NW 1 – 2: 1 capsule per day, in the morning between 8 and 9am.
Men older than 20 and younger than 35 with NW 3 – 4: 2 capsules per day, one capsule
in the morning between 8 and 9am and one capsule in the evening between 10 and 11pm.
Men older than 35 with NW 3 – 4: 2 capsules per day, one capsule
in the morning between 8 and 9am and one capsule in the evening between 10 and 11pm.
Women older than 25 with LUDWIG 1 – 3: 1 capsule per day, in the morning, between 8 and 9am.
Consult your dermatologist doctor or a specialist trichologist to establish the correct dosage for your specific situation.

SPECIAL PRECAUTIONS
KÉRATENE® alphactive retard is not suitable for pregnant women, during pregnancy or during the lactation period.
KÉRATENE® alphactive retard is not compatible with any other therapy based on synthetic 5aRD inhibitors or DHT
suppressors from the –steride group or with Flutamide / Bicalutamide. The combination of these therapies should be avoided
at all times. Because KÉRATENE® alphactive retard reduces the level of DHT androgen in the body, it may affect the
performance of professional athletes. It is recommended to interrupt the administration of KÉRATENE® alphactive retard
with at least 10 days before a competition. Consult your team physician or endocrinologist for professional medical advice
on the implications of low DHT and your athletic performance.

[HARIRI]

Yeah Yeah Yeah,

And yesterday Bart from Pro Hair Clinic said

"We had a lot of people requesting more tablets packaging to cover at least 3 months. The current version is 60 tablet, and it is recommended to use 1 tablet in the morning and 1 in the evening.

As of today the Keratene Retard Dht lowering tablets are available in 180 tablet version. Therefore the costs have been reduced as well, benefiting all that are interested in lowering DHT long term.
We ship virtually anywhere in the world : http://www.prohairclinic.be/

Bart"

That is what I could find so far. I will dig more into it...:-)

[GuyFromUK]

If we are going to test whether this product really reduces DHT levels or not then would anyone on the forum be prepared to do a test.

I.e. if there is a forum member who is not taking finasteride would they be prepared to do a blood test for their DHT levels, then take one of these capsules and then do a further DHT the next day test to see if their DHT levels have been reduced?

[Conpecia]

this sounds waaay too good to be true. You're telling me a side-free Fin substitute exists that's just come outta nowhere? Can't believe that at the moment, especially when the only documentation comes from the folks selling it. I generally go the opposite way of Tracy C but I totally agree with her here; we need independent verification.

[yeahyeahyeah]

If we are going to test whether this product really reduces DHT levels or not then would anyone on the forum be prepared to do a test.

I.e. if there is a forum member who is not taking finasteride would they be prepared to do a blood test for their DHT levels, then take one of these capsules and then do a further DHT the next day test to see if their DHT levels have been reduced?

I agree.

We need people to test this out.

[Jcm800]

Deffo, who's going to take one for the team?!

[yeahyeahyeah]

Deffo, who's going to take one for the team?!

I have a feeling that this product is legit tbh.

IT makes a lot of sense that you are less likely to get sides simply because 25% of DHT is inhibited as opposed to 90% like on fin.

But, I am maintaining at the moment, so not worth taking. Unless I know for sure that it works.