Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering

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  • WashedOut
    Senior Member
    • Dec 2011
    • 112

    Originally posted by Pate
    They are in Phase II and started it in January 2012. 3 month results should be available in the next few months.

    This is where Intercytex fell down. It's crunch time for Histogen. If they can improve on their Phase I results which were 20% increase in terminal hairs at 3 months (compared to Replicel's 3% at 6 months!) then I imagine they will have a marketable product.

    If they do an Intercytex then... well, Aderans is our last hope. And that is a particularly depressing thought.
    I'm glad people can actually appreciate Histogen's results now that they see how hard it is to gain that 20%. It's a pretty good showing and can be improved with time.

    Comment

    • UK_
      Senior Member
      • Feb 2011
      • 2744

      Originally posted by Pate
      If they do an Intercytex then... well, Aderans is our last hope. And that is a particularly depressing thought.
      Why do you say that?...



      they'll (Histogen) be releasing results at the SID in the coming week... does anyone plan on attending? lol

      Comment

      • Kiwi
        Senior Member
        • Mar 2011
        • 1105

        Originally posted by UK_
        Why do you say that?...



        they'll (Histogen) be releasing results at the SID in the coming week... does anyone plan on attending? lol
        Hey UK_, you know that video is showing off wigs right :P

        Anyway, just quickly, I'm curious as to how you know they (histogen) will be presenting next week. It's not on their site is it?

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        • BoSox
          Senior Member
          • Jun 2010
          • 708

          ugh, I feel like all these treatments will be to "prevent" hairloss not reverse it. By 2015 I won't have anything to prevent. I hope Histogen can help those who are NW 5 +

          Comment

          • tizzle
            Member
            • Apr 2012
            • 52

            correct me if i missunderstood the presented information but this HSC is actually regrowing and not preventing.

            Oh man my expectations are so high, it would kill me if this product fails during the trials (im very bad at keeping my hopes down)

            Comment

            • jpm
              Senior Member
              • Nov 2011
              • 250

              Originally posted by BoSox
              ugh, I feel like all these treatments will be to "prevent" hairloss not reverse it. By 2015 I won't have anything to prevent. I hope Histogen can help those who are NW 5 +
              Histogen had 73% regrowth. Infact their treatment doesn't prevent hair loss. It just regrows hair.

              Treatments like RU and CB will prevent hair loss

              Comment

              • kaandereli
                Member
                • Jan 2012
                • 57



                i got a sense of histogen by reading this article.it sounds a viable treatment and if comes to market it will make baldness just a trivial disease like flu.hope it comes out soon

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                • UK_
                  Senior Member
                  • Feb 2011
                  • 2744

                  Originally posted by Kiwi
                  Anyway, just quickly, I'm curious as to how you know they (histogen) will be presenting next week. It's not on their site is it?
                  Gail emailed me

                  Comment

                  • BoSox
                    Senior Member
                    • Jun 2010
                    • 708

                    Originally posted by jpm
                    Histogen had 73% regrowth. Infact their treatment doesn't prevent hair loss. It just regrows hair.
                    Did they really achieve this? I never realized they were able to do this. To have grown this much at such an early stage is amazing. I was so worked up on Replicel, I heard about Histogen before any future treatments but lost interest. Wouldn't this be considered a cure in your opinion?

                    Comment

                    • Davey Jones
                      Senior Member
                      • Apr 2012
                      • 356

                      Originally posted by BoSox
                      Did they really achieve this? I never realized they were able to do this. To have grown this much at such an early stage is amazing. I was so worked up on Replicel, I heard about Histogen before any future treatments but lost interest. Wouldn't this be considered a cure in your opinion?
                      I'm guessing that by "doesn't prevent hairloss", he means that the newly grown hairs are not DHT resistent and will suffer the same fate as the old ones, as they ARE the old ones.

                      Makes me wonder. If Replicel could prove that they could make follicles DHT resistant, despite not achieving impressive regrowth, then Histogen+Replicel would be a cure to hairloss, would it not?

                      That all would hinge on Replicel being able to show that they made follicles DHT resistant though. I heard that they thought they could, but I heard a lot of stuff from them.

                      Comment

                      • jpm
                        Senior Member
                        • Nov 2011
                        • 250

                        Bosox, they said they achieved 73% in a year on their site, so I assume they really did

                        Yes that's what I meant, the new follicles aren't DHT resistant but I believe the embryonic complex used by histogen will ''reset'' the follicle to where they were when they were first made. I.e. in the womb or as babies. Therefore I would assume that if you started losing your hair at 23 then Histogen would give you 23 more years.

                        However!! I also think that as a baby you have no DHT in your system until you reach puberty, which is around 13. So those follicles won't be immune for 23 years because DHT will be attacking them. I would assume that with Histogen those new hairs wouldn't start to thin for 10 years.

                        This is all my own take on it. Nothing concrete.

                        Comment

                        • john2399
                          Senior Member
                          • Jan 2012
                          • 527

                          Originally posted by Davey Jones
                          I'm guessing that by "doesn't prevent hairloss", he means that the newly grown hairs are not DHT resistent and will suffer the same fate as the old ones, as they ARE the old ones.

                          Makes me wonder. If Replicel could prove that they could make follicles DHT resistant, despite not achieving impressive regrowth, then Histogen+Replicel would be a cure to hairloss, would it not?

                          That all would hinge on Replicel being able to show that they made follicles DHT resistant though. I heard that they thought they could, but I heard a lot of stuff from them.
                          I like your way of thinking...combo of replicel and histogen could be genius. I still don't know how people are overlooking histogen thou. If this can have 73 percent regrowth in only phase 1, than who knows with more time how they can improve. Histogen is going to be a great treatment for people who are thinning and lost some hair, maybe not a cure to prevent hairloss but sure get alot of hair back. Im not sure it can save someone as of nw 6 or 7..thats the question

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                          • neversaynever
                            Senior Member
                            • Dec 2011
                            • 648

                            Im quite sure that 73% is just one patient, and not an average. Unless anyone can prove otherwise?

                            Comment

                            • Kiwi
                              Senior Member
                              • Mar 2011
                              • 1105

                              Originally posted by UK_
                              Gail emailed me
                              Getting emailed by the boss to let you know that is pretty significant! They are hardly going to email you to tell you that they are presenting if they know it's going to be shit :P

                              Comment

                              • tizzle
                                Member
                                • Apr 2012
                                • 52

                                even if its only 50% in average i still think its absolutely freakin amazing.

                                Many specialist say that you notice thinning when you lost 50% of the hair so for young people this means that they can get their HSC immediately and maybe keep all of the hair forever (in combination with Fin maybe)

                                and for people with progressed mph its still an amazing improvement

                                but i guess we have to wait and see how it works, if its even going to hit the market

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