Histogen's FINAL Phase I/IIa Results (2013)

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  • FearTheLoss
    Senior Member
    • Dec 2012
    • 1589

    Originally posted by KO1
    I believe doctors can prescribe it. If you can determine which vehicle to use, you can probably turn it into a solution.
    Hasson and Wong already prescribes it, but it doesn't have the film that was talked about at the last hair conference...it's a different formula.

    I contacted HW about it and they said they have seen good results with it, better than minox, but not as good as oral fin...and this is because they don't have the film that was added in the last study and presented at the conference.

    Comment

    • rdawg
      Senior Member
      • Jun 2012
      • 1019

      Originally posted by FearTheLoss
      Hasson and Wong already prescribes it, but it doesn't have the film that was talked about at the last hair conference...it's a different formula.

      I contacted HW about it and they said they have seen good results with it, better than minox, but not as good as oral fin...and this is because they don't have the film that was added in the last study and presented at the conference.
      sorry but what do you mean by film?

      Comment

      • FearTheLoss
        Senior Member
        • Dec 2012
        • 1589

        Originally posted by rdawg
        sorry but what do you mean by film?
        This was presented at the 7th World Congress for Hair Research

        Topical Finasteride Formulation: The swedes have come up with P-3074 which is a Finasteride 0.25% topical solution mixed with hydroxypropyl-chitosan (HPCH) which is a film-forming agent. They compared using this solution (once daily) with 1mg oral finasteride once daily and what they saw was mind boggling. Topical reduced scalp DHT by 71% whereas oral reduced it by 51%. Furthermore, serum DHT was reduced by about the same in both groups.

        The problem is, people with side effects will still have side effects because the serum DHT is reduced by the same amount...so hopefully they can find a happy medium where serum DHT is low and scalp DHT is still good enough for fin to do what we need it to do.

        The hydroxypropyl-chitosan is the film I was talking about.

        Comment

        • rdawg
          Senior Member
          • Jun 2012
          • 1019

          Originally posted by FearTheLoss
          This was presented at the 7th World Congress for Hair Research

          Topical Finasteride Formulation: The swedes have come up with P-3074 which is a Finasteride 0.25% topical solution mixed with hydroxypropyl-chitosan (HPCH) which is a film-forming agent. They compared using this solution (once daily) with 1mg oral finasteride once daily and what they saw was mind boggling. Topical reduced scalp DHT by 71% whereas oral reduced it by 51%. Furthermore, serum DHT was reduced by about the same in both groups.

          The problem is, people with side effects will still have side effects because the serum DHT is reduced by the same amount...so hopefully they can find a happy medium where serum DHT is low and scalp DHT is still good enough for fin to do what we need it to do.

          The hydroxypropyl-chitosan is the film I was talking about.
          Could I make this myself at home? how much is a years worth of HPCH?

          what about 0.5% topical, would that affect serum more? Im using proscar so its hard to cut the pills that small.

          Comment

          • Thinning87
            Senior Member
            • Dec 2012
            • 847

            can you people talk about this in a different thread?

            Comment

            • Javert
              Member
              • Jun 2013
              • 99

              Originally posted by Thinning87
              can you people talk about this in a different thread?
              Seriously.

              Comment

              • FearTheLoss
                Senior Member
                • Dec 2012
                • 1589

                You can make it at home, in the 7th world hair research thread..somewhere, it has the formula...

                and relax guys, histogen isn't going to have another update for 6 months plus...this thread is dead.

                Comment

                • Desmond84
                  Senior Member
                  • Oct 2012
                  • 987

                  It's now 1st of July 2013. It's been 7 months since Phase 1/2a finished and there is no indication that Phase 2b is going to start any time soon!

                  For Histogen, 2013 has been the hibernation year. There's been no investor meetings discussing plans and objectives for the Phase 2b protocol. There are NO milestones/targets in place and no real-time indication of a possible product release date.

                  If Histogen's troubles continue combined with the current economic climate, we may NOT see a Hair Stimulating Complex till 2017-2018 if ever!

                  Comment

                  • Thinning87
                    Senior Member
                    • Dec 2012
                    • 847

                    Originally posted by FearTheLoss
                    You can make it at home, in the 7th world hair research thread..somewhere, it has the formula...

                    and relax guys, histogen isn't going to have another update for 6 months plus...this thread is dead.
                    That's not the point, if you want to talk about something else other than Histogen then you should be in a different thread.

                    Originally posted by Desmond84
                    It's now 1st of July 2013. It's been 7 months since Phase 1/2a finished and there is no indication that Phase 2b is going to start any time soon!

                    For Histogen, 2013 has been the hibernation year. There's been no investor meetings discussing plans and objectives for the Phase 2b protocol. There are NO milestones/targets in place and no real-time indication of a possible product release date.

                    If Histogen's troubles continue combined with the current economic climate, we may NOT see a Hair Stimulating Complex till 2017-2018 if ever!
                    Relax dude, I know the Aderans news sucks but don't go into negative mode. We have no idea what Histogen has been up to and obviously if they are looking for partners they won't publicize the details of their negotiations

                    Comment

                    • yeahyeahyeah
                      Senior Member
                      • Nov 2011
                      • 1818

                      Originally posted by Desmond84
                      It's now 1st of July 2013. It's been 7 months since Phase 1/2a finished and there is no indication that Phase 2b is going to start any time soon!

                      For Histogen, 2013 has been the hibernation year. There's been no investor meetings discussing plans and objectives for the Phase 2b protocol. There are NO milestones/targets in place and no real-time indication of a possible product release date.

                      If Histogen's troubles continue combined with the current economic climate, we may NOT see a Hair Stimulating Complex till 2017-2018 if ever!
                      Why doesn't Spencer contact Gail and find out what's going on?

                      As much as Spencer is a 'consumer advocate', I don't feel he does enough for us.

                      The fact that Desmond found out about Aderans before Spencer did, is testament to it.

                      It's been 6 months, and we still dont know what's going on with histogen. How hard is it for him to check up with Dr Zeiring or Gail Noughton.

                      The same goes with Spex.

                      Joke industry.

                      Comment

                      • KO1
                        Senior Member
                        • Jan 2012
                        • 805

                        Is Spencer some sort of all-knowing being that is always up to date on clinical trials that are not public info? Spencer is marketing hair transplants, he does not know more about ARI than we do.

                        Comment

                        • 25 going on 65
                          Senior Member
                          • Sep 2010
                          • 1476

                          Spencer is legit. If he was actually a hair transplant marketer he would be worse at his job than anyone in the history of marketing, ever

                          Edit- For those who are new to the show/scene...

                          1 He recommends meds as a 1st line of defense before surgery, openly saying this is how he has avoided transplants

                          2 He recommends meds for anyone that has had surgery to avoid unnecessary future procedures

                          3 He is an advocate of concealer which he openly uses, saying it has helped him avoid transplants

                          4 He has turned away the majority of all IAHRS applicants as well as their $10k checks (or whatever it costs now for the screening/admission process)

                          5 He has told young guys not to get transplants as well as diffuse thinners, people with DUPA (thinning donor), etc

                          Comment

                          • Scientalk56
                            Senior Member
                            • Nov 2012
                            • 282

                            Originally posted by Desmond84
                            It's now 1st of July 2013. It's been 7 months since Phase 1/2a finished and there is no indication that Phase 2b is going to start any time soon!

                            For Histogen, 2013 has been the hibernation year. There's been no investor meetings discussing plans and objectives for the Phase 2b protocol. There are NO milestones/targets in place and no real-time indication of a possible product release date.

                            If Histogen's troubles continue combined with the current economic climate, we may NOT see a Hair Stimulating Complex till 2017-2018 if ever!
                            Yeah, it's a joke. and i really don't understand how could such thing happen. I mean, they have the most successful results. who is in charge of marketing and finding investors? because its seems like he's a failure. srsly.
                            Specially with such big number of companies trying to find a hair loss treatment, Histogen should hurry up.

                            Comment

                            • yeahyeahyeah
                              Senior Member
                              • Nov 2011
                              • 1818

                              Originally posted by 25 going on 65
                              Spencer is legit. If he was actually a hair transplant marketer he would be worse at his job than anyone in the history of marketing, ever

                              Edit- For those who are new to the show/scene...

                              1 He recommends meds as a 1st line of defense before surgery, openly saying this is how he has avoided transplants

                              2 He recommends meds for anyone that has had surgery to avoid unnecessary future procedures

                              3 He is an advocate of concealer which he openly uses, saying it has helped him avoid transplants

                              4 He has turned away the majority of all IAHRS applicants as well as their $10k checks (or whatever it costs now for the screening/admission process)

                              5 He has told young guys not to get transplants as well as diffuse thinners, people with DUPA (thinning donor), etc
                              The problem with Spencer is not that, its the fact that he has allowed histogen to be silent for 7 months.

                              Comment

                              • baldymcgee
                                Senior Member
                                • Mar 2013
                                • 118

                                Originally posted by yeahyeahyeah
                                The problem with Spencer is not that, its the fact that he has allowed histogen to be silent for 7 months.
                                Allowed them to be silent? I can't begin to fathom what this means?

                                Histogen has a PR department (or agency) ... Spencer can't *make* them talk.

                                Comment

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