Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering

[GBB]

The wait is killing me!

[GBB]

Ok, I got one more question if doctor Zerring is taking them--
The histogen Web site says that HSC causes new follicle formation, while doctor zerring seems to suggest that HSC promotes growth in existing follicles, even though they may have been dormant for a long long time. Am I missing something somewhere?
Now, is there a point of no return for a hair follicle? As in, can it atrophy to such a stage that it cannot be rejuvenated at all?

One hopes that HSC doesn't face any more delays, as we arent getting any younger or better. Also, whenever the treatment is approved in Asia, I hope all Asian countries have access to it. In my case, I'll be very selfish and hope it is available in India at least. There is a huuuuge market in this country with very little regulatory measures. People have made crores making a fool out of people. Plus the general lack of understanding makes it worse. I'll go a little off-topic and say that Spencer's effort has really motivated me to start something similar in my country. Hopefully, someday I'll be able to do it without getting embarrased about it.

[UK_]

Ok, I got one more question if doctor Zerring is taking them--
The histogen Web site says that HSC causes new follicle formation, while doctor zerring seems to suggest that HSC promotes growth in existing follicles, even though they may have been dormant for a long long time. Am I missing something somewhere?
Now, is there a point of no return for a hair follicle? As in, can it atrophy to such a stage that it cannot be rejuvenated at all?.

Well those are the questions we are all dying to know, we only had new research in January that suggests that no, follicles do not die off yet continue to produce microscopic hairs.

If you listen to the past interviews of the representatives of Histogen (i.e. Gail Naughton and Craig Ziering), they are stating that (1) HSC 'seems' to be inducing existing terminal hairs to grow more surrounding hairs per follicular unit and (2) that HSC seems to be signalling stem cells already in the scalp (possibly dormant follicles) to produce thicker hairs (as opposed to microscopic hairs).

[GBB]

Well those are the questions we are all dying to know, we only had new research in January that suggests that no, follicles do not die off yet continue to produce microscopic hairs.

If you listen to the past interviews of the representatives of Histogen (i.e. Gail Naughton and Craig Ziering), they are stating that (1) HSC 'seems' to be inducing existing terminal hairs to grow more surrounding hairs per follicular unit and (2) that HSC seems to be signalling stem cells already in the scalp (possibly dormant follicles) to produce thicker hairs (as opposed to microscopic hairs).

So the statement on the Histogen Web site about HSC 'inducing new follicle formation' is actually about activating progenitor cells? That clears things a little.

Now the only question is, when can I get my hands on it, if at all?

By the way, how do you suggest I keep some hair till the time HSC saves my life if I cannot take minox (tried it for 6-7 months, hair density became worse, caused severe adverse effects, acclerated the shedding)? I am a woman, 25 years old, so obviously Fin or Avodart is out of the question.

[RichardDawkins]

Nobody can for sure say what Histogen does, but one thing is clear it DOES something positive even in those early stages right now.

If you wanna keep your hair or try something, you should consider Acell/PRP as an option or at least something to look about. There was one doc here who showed one female hairloss patient with Acell/PRP

Here is the thread : http://www.baldtruthtalk.com/showthread.php?t=4604

[GBB]

Nobody can for sure say what Histogen does, but one thing is clear it DOES something positive even in those early stages right now.

If you wanna keep your hair or try something, you should consider Acell/PRP as an option or at least something to look about. There was one doc here who showed one female hairloss patient with Acell/PRP

Here is the thread : http://www.baldtruthtalk.com/showthread.php?t=4604

Yeah. HSC is the only hope to hang on to at the moment.

As far as the Acell/PRP thing is concerned, there are two concerns:

Problem No. 1: I am based in India. ACell does not ship the matristem micromatrix ,or, any device for that matter, internationally. It has no plans of doing so in the near future. I checked with them. Most dermatologists/hair restoration surgeons will have barely heard about PRP here. We still think HairMax is state-of-the-art!

Problem No. 2 : The pictures posted on that thread are called 'TEbefore', 'TEAfter' and so on. Try hovering the mouse over them and see. This leads me to believe that it was a case of Telogen Effluvium and not Androgenetic Alopecia from which I suffer.

So basically, you are a young balding person, you're jacked, you are a woman, you are twice as jacked, you live in a third-world country, you can just forget about a viable treatment. Life is such a bitch!

P:S: I suddenly feel somewhat better emotionally after joining this forum. Thank you for listening.

[RichardDawkins]

Yeah. HSC is the only hope to hang on to at the moment.

As far as the Acell/PRP thing is concerned, there are two concerns:

Problem No. 1: I am based in India. ACell does not ship the matristem micromatrix ,or, any device for that matter, internationally. It has no plans of doing so in the near future. I checked with them. Most dermatologists/hair restoration surgeons will have barely heard about PRP here. We still think HairMax is state-of-the-art!

Problem No. 2 : The pictures posted on that thread are called 'TEbefore', 'TEAfter' and so on. Try hovering the mouse over them and see. This leads me to believe that it was a case of Telogen Effluvium and not Androgenetic Alopecia from which I suffer.

So basically, you are a young balding person, you're jacked, you are a woman, you are twice as jacked, you live in a third-world country, you can just forget about a viable treatment. Life is such a bitch!

P:S: I suddenly feel somewhat better emotionally after joining this forum. Thank you for listening.

Ha you made me smiley, dont think about third world countrys as the only countrys witout state of the art techniques or ressources.

I live in germany, and as i said before here people are under the impression that FUE will be the most advanced "solution" ever and that FUT got a better yield then FUE

[UK_]

So the statement on the Histogen Web site about HSC 'inducing new follicle formation' is actually about activating progenitor cells? That clears things a little.

Now the only question is, when can I get my hands on it, if at all?

By the way, how do you suggest I keep some hair till the time HSC saves my life if I cannot take minox (tried it for 6-7 months, hair density became worse, caused severe adverse effects, acclerated the shedding)? I am a woman, 25 years old, so obviously Fin or Avodart is out of the question.

To be honest, the theory/literature behind WNT proteins (7A) is that they are upregulated in wound healing, so I am guessing they are signalling existing stem cells in the scalp to 'regenerate' more hairs per follicular unit, but there are no room for guesses, assumptions and false hope in the realm of scientific study.

This is true regenerative medicine, like Aderans, I am utterly convinced that it will work, my only concern is safety.

Obviously Histogen will know the final answer, by the way, you left out Aderans in your "list of hope", Histogen and Aderans are also conducting a real scientific study, not a hit and miss shot in the dark like other hyped procedures in the pipeline.

[CVAZBAR]

I have a feeling DOC Z has nothing good to say since he is lagging. I lost all hope.

[HairTalk]

Ha you made me smiley, dont think about third world countrys as the only countrys witout state of the art techniques or ressources.

I live in germany, and as i said before here people are under the impression that FUE will be the most advanced "solution" ever and that FUT got a better yield then FUE

I believe many experts currently in the field (as of March, 2011) do feel strip-harvesting tends to give higher yield than F.U.E.

[KeepTheHair]

Sorry to pounce on you, but I'm more than a little annoyed by your asking this question, even with your "disclaimer" about meaning no offense to anyone. Recent stories suggest the death-toll as a result of the events in Japan may be near 10,000; there still are massive problems concerning water, food, heat, shelter; nuclear plants seem not yet to be under control; literally countless lives have been damaged for a very long, if not indefinite, period, in the wake of the most powerful earthquake in the recorded history of the region.

For you to wander in to express concern to whether studies of a cosmetic product will be affected by all this, to my sentiment, is ****ing reprehensible.

Oh, just shut the **** up dude.



He was just wondering if it had any effect on the trials. Geezus. Grow a ****ing brain or shut the **** up. Hair loss is not just cosmetics it's a life altering thing. I know Japan faced worst but being curious about the damages to the trials is not doing anything you just choose to take offence. So shut the hell up.

[CAlex]

Thanks for seeing I wasnt trying to be a selfish a##hole keepTheHair

Hopefully your comments dont offend hairtalk too much and get us further off topic and into just arguing with each other.. We are all in this together and hopefully we stay on track for a 2013 life changer.

I think histogen is going to try their phase II in Singapore and I havent seen any major news concerning that location with the recent disaster.

[GBB]

I have a feeling DOC Z has nothing good to say since he is lagging. I lost all hope.

Doc Z said that Histogen would have the results in 4 weeks, doesn't necessarily mean he can share it immediately. I know its easy to get dissapointed, considering the barrage of false hopes that have been fed. But it would do no harm to wait a little before jumping to conclusions.

We have countless anxious people here, Doc Z, please put us out of our misery...

[UK_]

Doc Z said that Histogen would have the results in 4 weeks, doesn't necessarily mean he can share it immediately. I know its easy to get dissapointed, considering the barrage of false hopes that have been fed. But it would do no harm to wait a little before jumping to conclusions.

We have countless anxious people here, Doc Z, please put us out of our misery...

Exactly he said the results would be in at 4 weeks, and he planned to share the information with the hair loss community, it obviously takes time to first view/analyse the data, prepare it and reveal it to the public at mass. Have patience all, it will come, for better or worse.

[HairTalk]

Oh, just shut the **** up dude.



He was just wondering if it had any effect on the trials. Geezus. Grow a ****ing brain or shut the **** up. Hair loss is not just cosmetics it's a life altering thing. I know Japan faced worst but being curious about the damages to the trials is not doing anything you just choose to take offence. So shut the hell up.

Breathe in some radiation, then go die in several feet of water, you mindless waste of flesh.

Don't worry: beyond that response, I won't twist this thread any further off its path than it already has been. I was attacked, and I've replied, but it isn't my chief concern to successfully convey to someone on the Internet how a person might, in a time of this sort of catastrophe, have difficulty accepting the sort of comment made by CAlex to which I reacted (someone against whom I harbor no lasting animosity, and for whom, at any point, I had greater respect than I ever could for a juvenile idiot such as KeepTheHair).