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Old 10-10-2012, 01:34 PM   #1
frankJ
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Join Date: Sep 2012
Posts: 26
Default 5mg Finasteride Proscar

Hey guys, I've never posted before but I wanted to get in on this discussion. I took 5mg Proscar for years with out any sides, and it "appeared" to be more effective than when I took 1mg Propecia, although I have really no solid evidence (DHT serum levels, etc. ) that it did.

I do have a couple of questions about the effectiveness of 5mg vs 1mg finasteride though. I've seen the graph going around that shows that finasteride decreases DHT levels around 70% for dosages of 1mg to 5mg. So it would seem that taking 5mg is no more effective. However, my understanding is that finasteride as a treatment for enlarged prostate is to lower DHT levels. So if finasteride in really no more effective at lowering DHT levels at 5mg than at 1mg ( < 2% difference ) why is 5mg the standard protocol for treatment of enlarged prostate?

Also, I've seen the studies that GSK did comparing the effectiveness of Avodart to Proscar for treatment of MPB. I notice their studies compares 5mg Proscar to different dosages of Avodart. The effects of 1mg finasteride is never cited in their study. Does this mean GSK believes the optimal dose of finasteride to treat MPB is 5mg?

Just curious.
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Old 10-13-2012, 03:20 AM   #2
konfusion
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Join Date: May 2012
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well I am not so sure about this either, maybe 5 mg fin decreases serum DHT more than 1 mg but does not have a considerable effect on the scalp DHT? also 0.5 mg dutas decreases serum DHT by nearly 92% however it only decreases scalp DHT by 50% smth. I heard that 5 mg finas decreases scalp DHT by 38%.
so I was wondering, if I took 0.5 mg dut and 1 mg fin daily, can I decrease it more than 50%? or additional fin will not make a difference since dut is already stronger than fin?

PS: btw I am not looking to decrease my sex drive by 100% doing that actually that's the only thing that keeps me away from doing it
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Old 10-13-2012, 11:47 AM   #3
frankJ
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Join Date: Sep 2012
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Hey check out this link.

http://onlinelibrary.wiley.com/doi/1...909.x/abstract

It's a report of a guy who used finasteride daily and dutasteride weekly, seeing greatly improved results.
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