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Old 05-07-2012, 10:34 PM   #81
hellouser
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Yes, there were two injections. One was with DSC cells on one side and the other was a placebo injection on the other side. It was to see safety and efficacy in the localized area of only about 2 centermeters. So of course if they inject thousands of sites 2 cm apart on the scalp there would theoretically be hair growing throughout the treated area. But that's what they are working on. It's a long and arduous road. I still have hope but i'm running out of time.
So then why are people getting their pantys caught up in a bunch? Obviously the results are based on what I would consider a 'test run' and not the final and conclusive result. If I had to get a LOT of injections, even if over a period of time to get the desired result, I'd be perfectly fine with that.

My hair isnt terrible, ive got the widows peak/M pattern, but it isnt overly noticeable.

I do expect better results and they WILL come as more research is done on this baldness solution. Its a matter of seeing what works, what doesnt and how it can be improved on. Trial and error, more or less. Its really funny how ONE test run on a small number of people is supposedly the end result.

Some of the people on this forum are such negative nancys...
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Old 05-07-2012, 10:52 PM   #82
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Originally Posted by hellouser View Post
So then why are people getting their pantys caught up in a bunch? Obviously the results are based on what I would consider a 'test run' and not the final and conclusive result. If I had to get a LOT of injections, even if over a period of time to get the desired result, I'd be perfectly fine with that.

My hair isnt terrible, ive got the widows peak/M pattern, but it isnt overly noticeable.

I do expect better results and they WILL come as more research is done on this baldness solution. Its a matter of seeing what works, what doesnt and how it can be improved on. Trial and error, more or less. Its really funny how ONE test run on a small number of people is supposedly the end result.

Some of the people on this forum are such negative nancys...
You seem to have a good understanding. But I think when the news first broke out sufferers were looking for the holy grail and they were disappointed not to have it, as was I. But now that time has passed I have a better grasp on it. It's just that some of us are NW567 and we really are desparate for help. In this case, time is not on my side.
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Old 05-08-2012, 05:14 AM   #83
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It was stupid and damaging for people to jump on the RepliCel band wagon the way they did - especially given RepliCell hadn't even started phase 1 trials at the time.

It just set people up for a big crash and some major depression. Seriously not cool.

I hope next time everybody thinks twice before they go out and buy stock or tell new comers on this site that some miracle cure is going to be released by RepliCel anytime soon.

Anyway. Peace out. At least some of you can take fin
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Old 05-08-2012, 06:59 AM   #84
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It was stupid and damaging for people to jump on the RepliCel band wagon the way they did - especially given RepliCell hadn't even started phase 1 trials at the time.

It just set people up for a big crash and some major depression. Seriously not cool.

I hope next time everybody thinks twice before they go out and buy stock or tell new comers on this site that some miracle cure is going to be released by RepliCel anytime soon.

Anyway. Peace out. At least some of you can take fin
Yeah never understood what the fuss was about, was so stupid.
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Old 05-14-2012, 09:48 PM   #85
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There are many possible positive results. The one we all want to see is improved aesthetic coverage. Density changes alone are of no value. Think of body hair transplants. Sometimes we get good growth, but when you stand across the room, the transplants disappear. If you can't produce photos that show better coverage, density improvements by themselves are of no value. That was the problem with intercytex. they could grow hair, but you could only see it under high magnification if it grew at all.

Toss animal studies out altogether. Anyone and anything can grow hair on a mouse. The life span of the mouse has nothing to do with it.

If they are not willing to share efficacy photos, then I am highly suspect. While this was a safety study, they said they included parameters to show efficacy. If they can't show visible cosmetic improvement, then what they are growing is probably fine hairs that don't grow very long. This will not provide optimal coverage. Personally, I would not encourage investment in this product at this stage of development. They should produce cosmetically significant improvement or cease promoting their product until they have something that demonstrates cosmetically significant improvement.

Of course we all want them to keep trying and we all want them to succeed. What we don't want is for people to invest hard earned money in a product that grow vellus hair that you can feel but not see.

Personally, i took it from this interview that it is safe to inject your own cells back into you, but there are no photos that show improved coverage. Microscopically you can see a difference. Great! Have all your friends look at you under a microscope to show how full your hair is.
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Old 05-14-2012, 11:45 PM   #86
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Replicel is the one that is marketing there "unfinished" product with a nice site and nice animated videos of how easy it looks. On contrary it's very difficult and not for everybody..when you push info like that, add that to the overhype by some on this site plus promotion of trial results dates and personal interviews..well people are going to believe and they are going to expect progress.. Everyone here is not 20something with a long window but 40s50s60s with window closing w every day. There isnt much worse than to be bald in your 30-40s to hear a cure is coming in 5-10 years at best..
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Old 05-15-2012, 07:38 AM   #87
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There are many possible positive results. The one we all want to see is improved aesthetic coverage. Density changes alone are of no value. Think of body hair transplants. Sometimes we get good growth, but when you stand across the room, the transplants disappear. If you can't produce photos that show better coverage, density improvements by themselves are of no value. That was the problem with intercytex. they could grow hair, but you could only see it under high magnification if it grew at all.

Toss animal studies out altogether. Anyone and anything can grow hair on a mouse. The life span of the mouse has nothing to do with it.

If they are not willing to share efficacy photos, then I am highly suspect. While this was a safety study, they said they included parameters to show efficacy. If they can't show visible cosmetic improvement, then what they are growing is probably fine hairs that don't grow very long. This will not provide optimal coverage. Personally, I would not encourage investment in this product at this stage of development. They should produce cosmetically significant improvement or cease promoting their product until they have something that demonstrates cosmetically significant improvement.

Of course we all want them to keep trying and we all want them to succeed. What we don't want is for people to invest hard earned money in a product that grow vellus hair that you can feel but not see.

Personally, i took it from this interview that it is safe to inject your own cells back into you, but there are no photos that show improved coverage. Microscopically you can see a difference. Great! Have all your friends look at you under a microscope to show how full your hair is.
I often wondered about Replicel's marketing campaign. I imagine they really needed the money, or was just really confident in their technology. The problem is that if Replicel can't back up their talk they will lose credibility; as a scientist myself that is the last thing you want. From a scientific point of view they did create hair even it was only vellus hair, and you need a microscope to see it. The question is why does it create vellus but not terminal hair? If you can for example create significant qauntities of vellus hair but none of that vellus hair go terminal, it leads to interesting questions.

I don't think you can throw out animal studies altogether. It is likely true that any compound will grow hair on a mouse and the life expectancy of a mouse is a weak argument at best. But I believe that animal studies do have value. The researches had an idea which they tested on mice and they have taken that to human studies. If they end up a complete failure, fine at least they tried and we learnt something.
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Old 05-15-2012, 08:23 AM   #88
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There isnt much worse than to be bald in your 30-40s to hear a cure is coming in 5-10 years at best..
Surely you're not serious? Your comments are ignorant.
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Old 05-15-2012, 08:29 AM   #89
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The problem is that if Replicel can't back up their talk they will lose credibility; as a scientist myself that is the last thing you want
Very true. In my opinion, this has been Replicel's biggest mistake.
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Old 05-15-2012, 10:00 AM   #90
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Originally Posted by drcole View Post
There are many possible positive results. The one we all want to see is improved aesthetic coverage. Density changes alone are of no value. Think of body hair transplants. Sometimes we get good growth, but when you stand across the room, the transplants disappear. If you can't produce photos that show better coverage, density improvements by themselves are of no value. That was the problem with intercytex. they could grow hair, but you could only see it under high magnification if it grew at all.

Toss animal studies out altogether. Anyone and anything can grow hair on a mouse. The life span of the mouse has nothing to do with it.

If they are not willing to share efficacy photos, then I am highly suspect. While this was a safety study, they said they included parameters to show efficacy. If they can't show visible cosmetic improvement, then what they are growing is probably fine hairs that don't grow very long. This will not provide optimal coverage. Personally, I would not encourage investment in this product at this stage of development. They should produce cosmetically significant improvement or cease promoting their product until they have something that demonstrates cosmetically significant improvement.

Of course we all want them to keep trying and we all want them to succeed. What we don't want is for people to invest hard earned money in a product that grow vellus hair that you can feel but not see.

Personally, i took it from this interview that it is safe to inject your own cells back into you, but there are no photos that show improved coverage. Microscopically you can see a difference. Great! Have all your friends look at you under a microscope to show how full your hair is.
You should have said this before the announcement. So people could retract their money, I for one did get most of my money back.

But i'm sure a lot of people lost money and they were encouraged by me at the same time I told them it was going to fail before that so I hope they had enough time to sell their stocks and get a lot of their money back.

It is easy to down talk something after the announcement, it would have helped to have opinions from doctors working in this field before the announcement. We never got them.

Thanks for your input anyways.
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