Originally Posted by jpm
How would replicel work around the hairline? If you inject 10 times for example, along the hairline it will just be really patchy. I thought of you injected something into your scalp then in would spread out in a circle under the skin and the hairs would grow in a circle pattern. Not a problem on the top of your head because they will all overlap. But trying to create a straight hairline?
You don't actually WANT a totally straight hairline. HT docs deliberately create an irregular hairline because it looks more natural - some IMO go a bit overboard even.
With Replicel (and Histogen) the radius of action from an injection is believed to be about 2mm. So if those circles are 4mm apart and the hairs are going to be growing at random locations within that 4mm circle, you won't have to worry about the hairline looking weird, it should still look totally natural. If, for some reason, hair does grow up in weird places along the hairline you could get it removed, either surgically or, more likely, by laser hair removal.
Which would be kind of ironic, wouldn't it? "Yeah, had too much hair so I had to get some removed." Pretty much everybody here would like to be able to say that, I think.
Originally Posted by NotBelievingIt
RepliCel believes new folliciles might form, but its hard to say if that would absolutely happen. But if it does, thats why I believe a hairline HT might still be necessary to regain a non-haphazard hair line.
Well, they do have proof that new follicles form in mice, so it should happen in humans too. The question is whether it's going to be enough to fill in areas that are slick bald and too far gone for the follicles to regenerate. Probably not, judging by the mouse photos, or at least not yet.
I agree though, HTs may still be necessary. A lot of people are saying guys like Rassman oppose Replicel because it'll put them out of a job, but that's only true in the absolute best-case scenario, which Aderans has already shown isn't likely to happen. If Replicel restores damaged follicles and prevents further balding, maybe grows a few new hairs but not back to a full NW1, then I think HT docs are going to have MORE work, not less - a lot more. Because suddenly guys who are NW6 or heading there don't have to worry so much about running out of hair, and are going to need 1000-2000 grafts to perfect their hairlines and maybe fill in areas that didn't get good growth from Replicel.
For instance if you're like me, a full NW3 with a thinning NW6, and Replicel grows back my NW6 zone but only has spotty results in my slick bald NW3, then I'm going for FUE, not more Replicel. As it is, I've made the decision I'm not having any HTs because I know I don't have enough donor hair to make it look fully natural.