If it were PGD2.....

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • 2020
    Senior Member
    • Jan 2012
    • 1513

    #46
    Originally posted by gutted
    dude what are you talking about???

    i just found the answer to my own question
    ugh....

    NON-BALDING PERSON:
    anagen phase == follicle size: 500
    telogen phase == follicle size: 100

    do you agree that upon hair entering telogen phase, its follicle miniaturizes to 1/5 or whatever of its size? yes or no?

    Comment

    • gutted
      Senior Member
      • Jan 2011
      • 1397

      #47
      Originally posted by 2020
      ugh....

      NON-BALDING PERSON:
      anagen phase == follicle size: 500
      telogen phase == follicle size: 100

      do you agree that upon hair entering telogen phase, its follicle miniaturizes to 1/5 or whatever of its size? yes or no?

      telogen is just a resting phase.



      theres probably a tug of war between the prostglandins going on thats preventing full regenaration during "early to mid anagen phase" in the diagram.

      pgd2 is also upregulated inflammatory sites. Since inflamation is also part of mpb this would in effect triple pgd2 levels in balding scalp!!! Normal levels of pgd2 are not harmful at all, they regulate the hair cycle, its the excess pgd2 from the infalamtion which is the problem!

      Comment

      • 2020
        Senior Member
        • Jan 2012
        • 1513

        #48
        Originally posted by gutted
        telogen is just a resting phase.
        THIS WAS A YES OR NO QUESTION!

        follicle shrinks EVERYTIME a follicle enters telogen phase AND enlarges again as it enters anagen phase, AM I RIGHT?

        Comment

        • gutted
          Senior Member
          • Jan 2011
          • 1397

          #49
          Originally posted by 2020
          THIS WAS A YES OR NO QUESTION!

          follicle shrinks EVERYTIME a follicle enters telogen phase AND enlarges again as it enters anagen phase, AM I RIGHT?
          what do you mean skrinks? it doesn shrink, the hairs eject itself out during telogen.


          in mpb, the subsequent, anagen hair regrows thinner/minituraised

          in people without mpb, the subsequent anagen hair regrows normally and thick, rather than thinner/minturaised.

          Comment

          • 2020
            Senior Member
            • Jan 2012
            • 1513

            #50
            Originally posted by gutted
            pgd2 is also upregulated inflammatory sites. Since inflamation is also part of mpb this would in effect triple pgd2 levels in balding scalp!!! Normal levels of pgd2 are not harmful at all, they regulate the hair cycle, its the excess pgd2 from the infalamtion which is the problem!
            and how would Histogen stop that inflammation?

            Comment

            • 2020
              Senior Member
              • Jan 2012
              • 1513

              #51
              Originally posted by gutted
              what do you mean skrinks? it doesn shrink, the hairs eject itself out during telogen.
              why is it so hard to understand???

              THIS IS HOW HAIR WORKS FOR ALL PEOPLE:

              when the hair is in telogen phase, its follicle size is tiny, but once something tells that follicle to start growing hair again, its size increases and the follicle start making hair again(anagen phase)

              yes or no? follicle size goes up and down depending on what cycle it's on. this is just a fact why don't you know that?

              Comment

              • 2020
                Senior Member
                • Jan 2012
                • 1513

                #52
                Anagen Phase: The anagen phase is the “growing” phase of a
                hair follicle. It begins with a miniaturized hair follicle that may or may
                not have recently shed the hair it was growing during the previous
                growth cycle. At the beginning of the anagen phase, the hair follicle
                starts to grow back to full size
                and extend deeper into the skin.
                Catagen Phase: Following the anagen phase, the hair stops
                growing and the hair follicle starts shrinking.
                Telogen Phase: After the hair follicle has stopped shrinking, it
                enters the telogen or “resting” phase, which lasts for another three
                months, or so.
                ^ this is what I'm talking about. follicle size changes depending on which phase the hair is currently on. This is why Histogen would only be able to give you ONE ANAGEN CYCLE and after that all of your hair will fall out

                Comment

                • gutted
                  Senior Member
                  • Jan 2011
                  • 1397

                  #53
                  Originally posted by 2020
                  and how would Histogen stop that inflammation?
                  dude why do you keep on going on about histogen.

                  histogen works, how? i dont know, it supplies the growth factors neccasary for the hairs to regrow thick hair - yes it obviously affects the prostglandin cascade...it has to, everything is interrealted through negative feedback mechanims etc.

                  the hairs will last a very long time, but you need to address the inflammation yourself for it to last a lifetime. If you dont, it will begin to minuturise again, but hey...why would you worry about inflamation when you know you can inflame th f*** out of those follciles and still know you can get those follciles back through another histogen injection...

                  Comment

                  • 2020
                    Senior Member
                    • Jan 2012
                    • 1513

                    #54
                    Originally posted by gutted
                    histogen works, how? i dont know, it supplies the growth factors neccasary for the hairs to regrow thick hair - yes it obviously affects the prostglandin cascade...it has to, everything is interrealted through negative feedback mechanims etc.
                    yes but my point is that those growth factors will only last one hair cycle...

                    Comment

                    • gutted
                      Senior Member
                      • Jan 2011
                      • 1397

                      #55
                      Originally posted by 2020
                      yes but my point is that those growth factors will only last one hair cycle...
                      it will last 2/3 cycles, but expect minuturisation to take place after the 1st cycle.

                      Comment

                      • 2020
                        Senior Member
                        • Jan 2012
                        • 1513

                        #56
                        Originally posted by gutted
                        it will last 2/3 cycles, but expect minuturisation to take place after the 1st cycle.
                        how did you get 2-3 cycles? and i'm not talking about further miniaturisation due to DHT or whatever but rather from the fact that your follicles aren't able to regenerate again after a telogen phase

                        Comment

                        • gutted
                          Senior Member
                          • Jan 2011
                          • 1397

                          #57
                          Originally posted by 2020
                          ^ this is what I'm talking about. follicle size changes depending on which phase the hair is currently on. This is why Histogen would only be able to give you ONE ANAGEN CYCLE and after that all of your hair will fall out
                          use this for your info -

                          Hair Growth Cycle - Read more about our high-quality, natural and dependable results for men and women here.

                          Comment

                          • gutted
                            Senior Member
                            • Jan 2011
                            • 1397

                            #58
                            Originally posted by 2020
                            how did you get 2-3 cycles? and i'm not talking about further miniaturisation due to DHT or whatever but rather from the fact that your follicles aren't able to regenerate again after a telogen phase
                            dht wont be a problem after age 40-50 if that is the time you get the histogen injections.

                            they will be able to regenerate again on thier own.

                            Comment

                            • 2020
                              Senior Member
                              • Jan 2012
                              • 1513

                              #59
                              Originally posted by gutted
                              what for? I responded with: your body is able to enlarge and shrink follicles based on whatever cycle it's currently on. non-balding people can't do that - the follicle is stuck in resting phase.
                              HISTOGEN can provide some growing that will enlarge follicles again for ONE ANAGANE PHASE AGAIN but once it goes into telogen phase, you won't have the capability to turn them into anagen hair again....

                              why can't you understand what I'm saying?

                              Comment

                              • 2020
                                Senior Member
                                • Jan 2012
                                • 1513

                                #60
                                Originally posted by gutted
                                dht wont be a problem after age 40-50 if that is the time you get the histogen injections.
                                probably sure...

                                Originally posted by gutted
                                they will be able to regenerate again on thier own.
                                that is the assumption for most of you, but I'm saying no. Why would they be able to regenerate again? PGD2 is still there and it probably supresses all the natural growth factors that your body provides... this is getting hopeless but no one understands me

                                Comment

                                Working...