If it were PGD2.....
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telogen is just a resting phase.
theres probably a tug of war between the prostglandins going on thats preventing full regenaration during "early to mid anagen phase" in the diagram.
pgd2 is also upregulated inflammatory sites. Since inflamation is also part of mpb this would in effect triple pgd2 levels in balding scalp!!! Normal levels of pgd2 are not harmful at all, they regulate the hair cycle, its the excess pgd2 from the infalamtion which is the problem!Comment
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in mpb, the subsequent, anagen hair regrows thinner/minituraised
in people without mpb, the subsequent anagen hair regrows normally and thick, rather than thinner/minturaised.Comment
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pgd2 is also upregulated inflammatory sites. Since inflamation is also part of mpb this would in effect triple pgd2 levels in balding scalp!!! Normal levels of pgd2 are not harmful at all, they regulate the hair cycle, its the excess pgd2 from the infalamtion which is the problem!Comment
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THIS IS HOW HAIR WORKS FOR ALL PEOPLE:
when the hair is in telogen phase, its follicle size is tiny, but once something tells that follicle to start growing hair again, its size increases and the follicle start making hair again(anagen phase)
yes or no? follicle size goes up and down depending on what cycle it's on. this is just a fact why don't you know that?Comment
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Anagen Phase: The anagen phase is the “growing” phase of a
hair follicle. It begins with a miniaturized hair follicle that may or may
not have recently shed the hair it was growing during the previous
growth cycle. At the beginning of the anagen phase, the hair follicle
starts to grow back to full size and extend deeper into the skin.Catagen Phase: Following the anagen phase, the hair stops
growing and the hair follicle starts shrinking.Telogen Phase: After the hair follicle has stopped shrinking, it
enters the telogen or “resting” phase, which lasts for another three
months, or so.Comment
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dude why do you keep on going on about histogen.
histogen works, how? i dont know, it supplies the growth factors neccasary for the hairs to regrow thick hair - yes it obviously affects the prostglandin cascade...it has to, everything is interrealted through negative feedback mechanims etc.
the hairs will last a very long time, but you need to address the inflammation yourself for it to last a lifetime. If you dont, it will begin to minuturise again, but hey...why would you worry about inflamation when you know you can inflame th f*** out of those follciles and still know you can get those follciles back through another histogen injection...Comment
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yes but my point is that those growth factors will only last one hair cycle...Comment
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how did you get 2-3 cycles? and i'm not talking about further miniaturisation due to DHT or whatever but rather from the fact that your follicles aren't able to regenerate again after a telogen phaseComment
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they will be able to regenerate again on thier own.Comment
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HISTOGEN can provide some growing that will enlarge follicles again for ONE ANAGANE PHASE AGAIN but once it goes into telogen phase, you won't have the capability to turn them into anagen hair again....
why can't you understand what I'm saying?Comment
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that is the assumption for most of you, but I'm saying no. Why would they be able to regenerate again? PGD2 is still there and it probably supresses all the natural growth factors that your body provides... this is getting hopeless but no one understands meComment
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