Spencer Kobren Interviews Dr. Jerry Cooley | ACell MatriStem Plucked Hair

Join Spencer Kobren, and the crew of The Bald Truth for a couple of beers and good times in our live chat tonight @ 7pmPST/10pm EST

Live on the home page of http://www.thebaldtruth.com

Tonight's Special Guest: Dr. Gary Hitzig
Call the studio line to ask Dr. Hitzig your questions: 1-888-659-3727

Also remember, you can now view the show and chat on your mobile phone.

See how here:
http://www.thebaldtruth.com/news/bal...-mobile-phone/

Hope to see you tonight!

So excited for the show. Anyone going to call in and ask Dr hitzig Questions?

For all who have heard the live show with Dr Hitzig.... He has mentioned more then once that hes able to perserve donor hair in strip procedures and use the same are more then once. What i dont get is why Dr Cooley is not saying the same thing. This is the anwser i got regarding this from Dr Cooleys office

"In a traditional excision we do a closure called “tricophytic”. This closure allows for hair to grow directly into the incision. You also have the option to use ACell with this procedure. The fee for adding ACell is $500 which is cost only.
I do want to clarify, in a strip, the hair is not preserved, it is excised, removed and the area is closed with sutures. In the closure we use the edge of the wound is trimmed away at an angle and the opposing side of the wound is not just pulled closed but overlapped allowing the bottom edge of hair to grow into the incision. The addition of ACell insures that the tissue that is regenerated in normal tissue vs scar. It is flatter and does not have the think white appearance of a regular scar."

miozambrotta19,

have you heard if cooley is doing injections into the scalp with the arterial blood and acell?

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Originally Posted by miozambrotta19

For all who have heard the live show with Dr Hitzig.... He has mentioned more then once that hes able to perserve donor hair in strip procedures and use the same are more then once. What i dont get is why Dr Cooley is not saying the same thing. This is the anwser i got regarding this from Dr Cooleys office

"In a traditional excision we do a closure called “tricophytic”. This closure allows for hair to grow directly into the incision. You also have the option to use ACell with this procedure. The fee for adding ACell is $500 which is cost only.
I do want to clarify, in a strip, the hair is not preserved, it is excised, removed and the area is closed with sutures. In the closure we use the edge of the wound is trimmed away at an angle and the opposing side of the wound is not just pulled closed but overlapped allowing the bottom edge of hair to grow into the incision. The addition of ACell insures that the tissue that is regenerated in normal tissue vs scar. It is flatter and does not have the think white appearance of a regular scar."

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That means, Dr. Hitzig IS able to successfully accomplish such procedures (regrowth/regeneration of harvested donor strips - INCLUDING hair follicles!), whereas Dr. Jones failed in his 1st Acell-experiment (2008/2009)?

http://www.drrobertjones.com/2009/01...s-post-op.html

@Spencer and listeners - Did Dr. Hitzig really mentioned exactly this - more than once?

Mkamph:
I dont think Dr Cooley offers the injection, but try and email them and see if its eomthing hes willing to do. I havent heard anything along the lines of him doing this procedure.

HairRobinhood:
If you listen to his presentations he mentions it and he mentioned it last night on the live show. Im not sure if im getting something wrong or this is really the case. Somone called into the show and mentioned he was going to Dr cooley for an autocloning procedure, and Dr Hitzig responded by saying you should get the strip because the hairs can be regenerated and used again. Im trying to find out if this is true.

Would shock loss in the recipient site still be a potential problem?

Is it possible to listen the recorded live interview with Hitzig?

I had a thought. It has been concluded by Follica and Histogen when WNT proteins are introduced to wounded skin, an embroyonic healing state takes place and thus new hair follices are produced. Would it be possible to add these Wnt proteins to the Acell/PRP injections and then introduce this to the scalp?
I think most of what you would need would be in these 3 things.
PRP-adults stem cells-growth factors
Acell-Helps adult stem cell return to an embryonic state during healing,Contains a host of proteins, growth factors, collagen ect.
WNT Proteins-What is needed to induce the formation of new hair follices.

Histogen is basing there experiment of Wnt Proteins and has show great results in the early trials
Follicas whole experiment is based on wnt proteins-They have tried in on bald mice and all have grown new hairs
So what im sayign is why not try this with humans with prodcuts that are both FDA apporved and with WNT which is a natural protein in the body.

Quote:

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Originally Posted by miozambrotta19

I had a thought. It has been concluded by Follica and Histogen when WNT proteins are introduced to wounded skin, an embroyonic healing state takes place and thus new hair follices are produced. Would it be possible to add these Wnt proteins to the Acell/PRP injections and then introduce this to the scalp?
I think most of what you would need would be in these 3 things.
PRP-adults stem cells-growth factors
Acell-Helps adult stem cell return to an embryonic state during healing,Contains a host of proteins, growth factors, collagen ect.
WNT Proteins-What is needed to induce the formation of new hair follices.

Histogen is basing there experiment of Wnt Proteins and has show great results in the early trials
Follicas whole experiment is based on wnt proteins-They have tried in on bald mice and all have grown new hairs
So what im sayign is why not try this with humans with prodcuts that are both FDA apporved and with WNT which is a natural protein in the body.

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Yeah, also been wondering if Acell can be used in a different want than just transplants.

Can someone comment on this please?

thanks

On last nights live show, Spencer said he would be interviewing Craig Ziering of Histogen "Very Soon"

Maybe some exciting news?

Do you know when the interview might be?
Maybe they might talk about the upcoming 1 and 2 trails in Singapore

Dr. Epstein shown with his male patient 1 and 2 days after a hair transplant procedure of 2378 FUE grafts. The procedure also involved autocloning about 450 grafts plucked from the beard that were placed in the crown region using ACell MatriStem. ACell MatriStem, an exciting new development in regenerative technology, was used to help these hairs regrow better in the scalp.

Here is the original post:

http://www.baldtruthtalk.com/showthr...8590#post18590

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Originally Posted by miozambrotta19

Do you know when the interview might be?
Maybe they might talk about the upcoming 1 and 2 trails in Singapore

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All he said was "very soon", and that he would be interviewing craig Ziering

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Originally Posted by Westonci

On last nights live show, Spencer said he would be interviewing Craig Ziering of Histogen "Very Soon" Maybe some exciting news?

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Or maybe some not-so-exciting news:

Dr. David Easter Joins Histogen Scientific Advisory Board

Histogen, Inc., a regenerative medicine company developing solutions based on the products of newborn cells grown under embryonic conditions, today announced the addition of respected surgeon and oncology specialist Dr. David Easter to the Company's Scientific Advisory Board.

http://www.benzinga.com/press-releas...advisory-board

Thats not bad news. Just shows that histogen is bringing on more respected doctors onto there board. This is something possitive if you ask me. Looking forward to the Zieirng interview.

What a hopeful time! Between Aderans, Histogen and ACell (not to mention CB-03-01), it looks like some real work is being put into a desicive death-by-fork-in-the-eye for our inherited genetic nemesis.

!!!

Quote:

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Originally Posted by miozambrotta19

Thats not bad news.

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Didn't say it was. I just said that it might not be considered "exciting" news.

Only true hope we have right now is Acell. Yes Aderans and Histogen are making good progress but who knows what will happen with there trails. I just hope that by summer we will have good news from both of these companies. We all know what happend with Intercynx , and they were in there second trials after that went to crap. I dont understand why Follica is taking so long to get trials going. In 2005 they were talking about bringing there technology to market and they havent even started trials. Trichoscience should be starting there first trials next month, but Follica confuses me. It almost seems as if there waiting for Histogen of Aderans to fail so they have something to look forward to. IDk lets wait and see.

If anyone is in direct contact with Acell, Dr Cooley, Of Dr Hitzug, they should ask if it would be possible to add Wnt proteins to the Acell/PRP injections. I mentioned this before in my previous post, but it would be interesting to know if this would be possible. Wnt proteins have been to shown to grow new follicles in mice when it was introduced to a wound in mice. With Acell And PRP being FDA approved , and wnt proteins being natural proteins in the human body, why couldnt this be tried on humans. Aderans and Histogen are basing there technology on Wnt proteins, and Dr Cotsarelis has said that with adding Wnt proteins, growth factors, ect totally new hairs grew on mice. With Acell/PRP/WNt most fo what is said to be needed is there.

Quote:

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Originally Posted by miozambrotta19

Do you know when the interview might be?
Maybe they might talk about the upcoming 1 and 2 trails in Singapore

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In tonights live show, he said hopefully next week he will speak to either Craig Ziering and or Gail Naughton

Dr Epstein Using Acell

[/QUOTE]

[/QUOTE]

I dont understand why hes using beard hairs? Dr. Cooley said that scalp hairs where more effective, and creating a fuller look in his third video of his presentation

http://www.iahrs.org/news/dr-jerry-c...tion-part-3-4/

http://www.socaltech.com/histogen_ra...s-0032513.html

Histogen Raises $10M

San Diego-based Histogen, a developer of regenerative medicine products, announced today that it has raised $10M in a Series A financing round. The financing came from private investors, including Secure Medical, Leonard Lavin, Lordship Ventures, and Angus Mitchell. Histogen is developing regenerative medicine products which do not contain embryonic stem cells or animal components, and are being applied to hair regrowth, skincare, and oncology. The firm said it is in the midst of a $23M, Series B financing which already has commitments. Histogen said it is scheduled to begin a Phase I/II clinical trail of a hair stimulating product in Spring 2011, and is also in the process of beginning a clinical study for a compound for the treatment of carcinomatosis.

Dr. Cole on ACell – Part 1 – 4:
http://www.*************/hair-loss/bo...ategory-1.html

Just to quote 1 user-comment:

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“…so it seems to me that Dr Cole is effectively saying Drs Cooley and Hitzig are either idiots or liars.”

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Dr. Cole on ACell – Part 1 – 4:
http://www.*************/hair-loss/bo...ategory-1.html

Just to quote 1 user-comment:

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“…so it seems to me that Dr Cole is effectively saying Drs Cooley and Hitzig are either idiots or liars.”

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The sour grapes of a renowned egomaniac. This is a guy who apparently tried to sue his former tech to stop him from going to another HT clinic.

Rather than contribute to this advancement, Dr. Cole appears to be trying to marginalize it so as to preserve the relevance of his "CIT" (aka reguar FUE) sales.

One thing he kept mentioning was that the plucked Acell hairs grow back thinner than a regular transplanted hair. Somebody please confirm that Dr. Cole and Dr. Hitzig are claiming these results. I did see a pic where the hairs growing in were thinner, but understood that to be because they were just starting to sprout, and like any hair transplant, take time to mature. Dr. Cole is saying that auto-cloned hairs remain thinner than normal forever.

Spencer, can we get confirmation on this from either Hitzig or Cooley? Cheers.

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Originally Posted by wolvie1985

The sour grapes of a renowned egomaniac. This is a guy who apparently tried to sue his former tech to stop him from going to another HT clinic.

Rather than contribute to this advancement, Dr. Cole appears to be trying to marginalize it so as to preserve the relevance of his "CIT" (aka reguar FUE) sales.

One thing he kept mentioning was that the plucked Acell hairs grow back thinner than a regular transplanted hair. Somebody please confirm that Dr. Cole and Dr. Hitzig are claiming these results. I did see a pic where the hairs growing in were thinner, but understood that to be because they were just starting to sprout, and like any hair transplant, take time to mature. Dr. Cole is saying that auto-cloned hairs remain thinner than normal forever.

Spencer, can we get confirmation on this from either Hitzig or Cooley? Cheers.

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Im also wondering where dr Cole got his info from regarding the "supposed" thinned plucked hair. Im sure that Doctor Rassman or bernstein would have mentioned it in their analysis, but they have not heard of this yet.

It sound like to me that dr Cole is hiding something

Guys, I had a corrective procedure done with Dr. Cole a month ago. I am a fan of the guy and will not say anything bad about him. But, I did ask him his opinion on Dr. Cooley's work and he was unaware of it. I told him about it and he was skeptical but said it sounded interesting. I doubt Dr. Cole has done a whole lot of work to disprove this method over the past four weeks and he is probably just a general skeptic when it comes to these advancements, which is healthy because all new technology should be challenged. I wouldn't get too upset about it.

When do you guys think we will have a clearer picture of what A-cell can do for us balding men?
Bascially, the only thing that is stopping me from having a hair transplant is whether or not A-cell works. If it does work I will not have to worry about my transplant looking weird in the future because of not having enough donor.

In my eyes it is already proven that a plucked hair will regrow with a success rate of 50-75 % with Dr. Cooley using A-cell. It seems the only issue is that we do not know if the hair will cycle normally.
But considering that the hair has probably already gone into resting phase when it was transplanted, and then started growing - it seems that things are pointing toward that it will cycle as it should.

But how long do you think a definite answer to this will take?
Also, are there any other issues that I fail to see?

With all this talk about Acell, I am surprised that no one on this forum, including Spencer, has brought up the news this week about stem cell research.

I am referring to the report that stem cells have been used, for the very first time, to create a living hair follicle. This report comes from Ronald Lauster at Berlin Technical University. The news has been reported in the popular media during the past few days. Spencer, what do you think about this news? The guy predicts people will be able to use this in 5 years.

Quote:

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Originally Posted by CVAZBAR

With all this talk about Acell, I am surprised that no one on this forum, including Spencer, has brought up the news this week about stem cell research.

I am referring to the report that stem cells have been used, for the very first time, to create a living hair follicle. This report comes from Ronald Lauster at Berlin Technical University. The news has been reported in the popular media during the past few days. Spencer, what do you think about this news? The guy predicts people will be able to use this in 5 years.

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He talked it briefly about it last Sunday during his radio show.

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Originally Posted by ryan555

I am an investor in Histogen. The plan is still to release the HSC in Asia (excluding Japan) in 2013, and in the US and Europe by 2015. They are conducting their next trial phase in Singapore in February. I am assuming that if this product does everything it is supposed to do, most of you will figure out a way to get to Asia.

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HOw much you think this would cost and what would the procedure be? Injections? How many times?

Quote:

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Originally Posted by ryan555

I am an investor in Histogen. The plan is still to release the HSC in Asia (excluding Japan) in 2013, and in the US and Europe by 2015. They are conducting their next trial phase in Singapore in February. I am assuming that if this product does everything it is supposed to do, most of you will figure out a way to get to Asia.

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If Phase II is successful why cant histogen skip phase III and offer the injections at full price in black markets such as Mexico, India, or in International Waters if necessary?

I dont care how much it costs, time is not on my side.

i note that there are some unanswered questions that I think Dr Hitzig and Dr Cooley alluded to particularly about hair cycling and androgen sensitivity. I am a little baffled as to why they dont already know the anwsers to these.

Dr Hitzig did have some success with plucking in the past. This process is no different except Acell is used to increase effectiveness. So there are already plucked hair (pre 2005) patients walking amongst us. Of course they might not know if plucked head hair never worked.

do the hairs cycle and good quality?
any dr hitzig pre2005 plucked hair (not beard) patient care to answer this question ? although the additon of acell has the potential to improve quality.

are plucked hairs androgen sensitive ?
not sure about this, is there a test to check androgen sensitivity of the new follicle. otherwise any pre2005 Dr Hitzig plucking patients that had plucked scalp hair success out there still have this non miniturised hair growing, even if only a few took hold ?

Quote:

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Originally Posted by rapunzal

i note that there are some unanswered questions that I think Dr Hitzig and Dr Cooley alluded to particularly about hair cycling and androgen sensitivity. I am a little baffled as to why they dont already know the anwsers to these.

Dr Hitzig did have some success with plucking in the past. This process is no different except Acell is used to increase effectiveness. So there are already plucked hair (pre 2005) patients walking amongst us. Of course they might not know if plucked head hair never worked.

do the hairs cycle and good quality?
any dr hitzig pre2005 plucked hair (not beard) patient care to answer this question ? although the additon of acell has the potential to improve quality.

are plucked hairs androgen sensitive ?
not sure about this, is there a test to check androgen sensitivity of the new follicle. otherwise any pre2005 Dr Hitzig plucking patients that had plucked scalp hair success out there still have this non miniturised hair growing, even if only a few took hold ?

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I think i remember hearing that the process on plucking hairs now with Acell is different because it needed to be plucked with the epithelial tissue included, which is different from the past. As for the sensitive androgen, it would also take time since this this type of plucking is different. You can read more and look for yourself in other threads because im not sure exactly what's the difference.

possibly, perhaps Dr H could clarify but I presume that its the same concept as Dr H used sometime back however they might have improved the technique. I mean, the hair shaft would be useless without the cells attached, i would think the same would have applied back in the early days.

on another note i notice that a few people believe this would be an adjunct to existing hair transplant methods. this has be baffled, i mean why would this not become the "gold standard" and only method IF it is successful.

what does traditional STRIP and FUE offer that this potentially couldn't ?
only one thing comes to mind and that is an entire FU in its natural state and even then, Dr C in one of his presentations showed that he placed multiple hairs in a single slot to mimic a natural FU so apart from this ... nothing

Quote:

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Originally Posted by rapunzal

possibly, perhaps Dr H could clarify but I presume that its the same concept as Dr H used sometime back however they might have improved the technique. I mean, the hair shaft would be useless without the cells attached, i would think the same would have applied back in the early days.

on another note i notice that a few people believe this would be an adjunct to existing hair transplant methods. this has be baffled, i mean why would this not become the "gold standard" and only method IF it is successful.

what does traditional STRIP and FUE offer that this potentially couldn't ?
only one thing comes to mind and that is an entire FU in its natural state and even then, Dr C in one of his presentations showed that he placed multiple hairs in a single slot to mimic a natural FU so apart from this ... nothing

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I think the question is (in general), does it make sense (besides the necessary effort) to do so in the daily clinical praxis? How about plucking of the natural hair groupings all at once?

http://www.hasci.com/uploads/downloa...%20Neumann.pdf

hhmm very interesting approach, FUE with transection, theoretically sounds good but would need improved extraction tools and highly skilled Doctor to maintain accuracy and increase the number of hair extraction per minute. I wonder how many grafts Dr Woods extracted per minute when he started FUE.

Quote:

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Originally Posted by miozambrotta19

The latest updte is that they are still planing to release something in Asia(not japan) in 2013, and for introduction in America by 2015. Again this is all on the notion that phase 1 and 2 go well and that they are able to get quick funding for the phase 3 trials. We will have to wait till summer to see the early results. If anyone wants to email them, they can go to the Histogen website and find the emails. If the these first 2 trials go well we should more then likely see fast funding. Lets just hope this happens.

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Your post was on November 14, 2010. Since then on December 1st Histogen announced that they completed Series A Financing.

In your post you said that if Histogen gets quick funding then we may see 2013 as being a strong possibility.

Is it possible that Histogen may speed up clinical trials with the heating up of competition coming from Latisse's new trials, Follicas recent annoucnemnt by Dr. Cotsarelis, Berlin Institute making artificial hair, Acell, etc.

Wow this is amazing, if more research goes into using Matristem with plucked hairs, than 2010 may be the year that baldness was finally cured!!!