hsc update

[matlondon]

HSC is currently in a Phase I/II clinical trial in the Philippines. We look forward to sharing data from that trial in the coming months. Due to the timelines associated with clinical trials and regulatory approval, the estimated timeframe for market availability of HSC continues to be 2015/2016 within the US. There is a possibility of earlier introduction in certain Pan-Asian countries, and plans for additional regions have not yet been finalized.



Histogen intends to bring HSC to market through partnerships with industry leaders in various regions. As such, it will be our partner that ultimately determines the market price point. We are likely to have a better idea for potential price range as HSC gets closer to market.

[HairTalk]

HSC is currently in a Phase I/II clinical trial in the Philippines. We look forward to sharing data from that trial in the coming months. Due to the timelines associated with clinical trials and regulatory approval, the estimated timeframe for market availability of HSC continues to be 2015/2016 within the US. There is a possibility of earlier introduction in certain Pan-Asian countries, and plans for additional regions have not yet been finalized.



Histogen intends to bring HSC to market through partnerships with industry leaders in various regions. As such, it will be our partner that ultimately determines the market price point. We are likely to have a better idea for potential price range as HSC gets closer to market.

Who are you? Do you represent Histogen?

[2020]

Who are you? Do you represent Histogen?

doubt it... he registered at 2010 and has 68 posts.
Why would histogen need to advertise themselves? Pretty sure all of us are already aware of them and patiently waiting for their "cure".

[matlondon]

Who are you? Do you represent Histogen?

No, but i try and get info about hair growth because i'd like to use it one day.

[clandestine]

matlondon; If you'd like to post updates regarding the progress of upcoming treatments, please post the source from which you gathered the information. A url would suffice just fine.

Also, such information might be better suited posted in their respective threads ((in this case) i.e. "Histogen Update - Spencer Kobren Speaks With Dr. Craig L. Ziering")

Cheers.

[NeedHairASAP]

HSC is currently in a Phase I/II clinical trial in the Philippines. We look forward to sharing data from that trial in the coming months. Due to the timelines associated with clinical trials and regulatory approval, the estimated timeframe for market availability of HSC continues to be 2015/2016 within the US. There is a possibility of earlier introduction in certain Pan-Asian countries, and plans for additional regions have not yet been finalized.



Histogen intends to bring HSC to market through partnerships with industry leaders in various regions. As such, it will be our partner that ultimately determines the market price point. We are likely to have a better idea for potential price range as HSC gets closer to market.

you could probably do without using the word "we" if there is no we

[Pate]

Histogen intends to bring HSC to market through partnerships with industry leaders in various regions. As such, it will be our partner that ultimately determines the market price point. We are likely to have a better idea for potential price range as HSC gets closer to market.

Urgh, I don't like the sound of that.

The "industry leaders" in our various regions are largely charlatans charging vulnerable people ridiculous amounts for dubious treatments like lasers and saw palmetto pills.

Can you imagine what'll happen if these bastards get their hands on something that actually WORKS?

Hopefully Histogen refuse to license it to any one company and allow smaller clinics access to the technology as well, so that the market can set the price instead of letting one big company screw us all over again.

[2020]

Urgh, I don't like the sound of that.

The "industry leaders" in our various regions are largely charlatans charging vulnerable people ridiculous amounts for dubious treatments like lasers and saw palmetto pills.

Can you imagine what'll happen if these bastards get their hands on something that actually WORKS?

Hopefully Histogen refuse to license it to any one company and allow smaller clinics access to the technology as well, so that the market can set the price instead of letting one big company screw us all over again.

this is crazy... no one even knows if histogen is going to work and you're all already arguing about the price!?

Even if it costs 50K, I wouldn't care... at least I'll know that there are options

[tonypizza]

this is crazy... no one even knows if histogen is going to work and you're all already arguing about the price!?

Even if it costs 50K, I wouldn't care... at least I'll know that there are options

Isn't that the truth

If a cure comes out, how many people would be perfectly happy being bald knowing that if they really wanted, they could change it. It's the hopelessness of baldness that's the real killer

[Conpecia]

Isn't that the truth

If a cure comes out, how many people would be perfectly happy being bald knowing that if they really wanted, they could change it. It's the hopelessness of baldness that's the real killer

This.

Let's worry about curing it first. Where did the OP get this info? And next time please let us know if you're getting this from the grapevine and aren't actually with Histogen. I got excited for no reason. Anyways, please post a link to your source good sir.

[Maradona]

This.

Let's worry about curing it first. Where did the OP get this info? And next time please let us know if you're getting this from the grapevine and aren't actually with Histogen. I got excited for no reason. Anyways, please post a link to your source good sir.

he probably got it by emailing them, or you could do a google search type hystogen and the time it coulda been published i.e. 24H~ 1 week.

That's how i look for news about replicel.

We should have an idea how bald we will be for the rest of our lives by this summer. For me it's april but that's only because i put all my money in replicel :cool: .

[Conpecia]

he probably got it by emailing them, or you could do a google search type hystogen and the time it coulda been published i.e. 24H~ 1 week.

That's how i look for news about replicel.

We should have an idea how bald we will be for the rest of our lives by this summer. For me it's april but that's only because i put all my money in replicel :cool: .

If a 2015/16 street date was set in stone I would sleep like an infant on melatonin every night for the next three years. Too much can go wrong between now and then. Guess I should just chill until April though...

You will be a rich man if Replicel holds the key, perhaps you will pay for my treatment? :D

[DepressedByHairLoss]

Isn't that the truth

If a cure comes out, how many people would be perfectly happy being bald knowing that if they really wanted, they could change it. It's the hopelessness of baldness that's the real killer

Amen to that Tony. I'd pay or do anything to cure my own hair loss except unfortunately we're stuck with such shitbag options like Rogaine, Propecia, and hair transplants, not to mention utterly useless garbage like herbal treatments or shampoos that supposedly "nourish the scalp". It really frustrates me because we all so desperately want to cure our own hair loss and would pay loads of money to do so, yet we're not given any decent options to cure it or even treat it.

[ccmethinning]

If a 2015/16 street date was set in stone I would sleep like an infant on melatonin every night for the next three years. Too much can go wrong between now and then. Guess I should just chill until April though...

You will be a rich man if Replicel holds the key, perhaps you will pay for my treatment? :D

Ugh its gonna be so hard not to get hopes up. Can you imagine the feeling knowing that a legitimate treatment is only a 4 years off? It will be crushing if April comes and Replicel announces they achieved 0% results. 10-15% I can live with, because the methodology can be improved and hopefully compounded, but if the result is 0%, then this generation of hair loss sufferers is probably screwed.

[Maradona]

If a 2015/16 street date was set in stone I would sleep like an infant on melatonin every night for the next three years. Too much can go wrong between now and then. Guess I should just chill until April though...

You will be a rich man if Replicel holds the key, perhaps you will pay for my treatment? :D

I only put 500 bucks Bro, that might pay half my treatment IF everything goes well. If everything goes extremely well, there's no reason why I wouldn't help a bald brothah out :p.

[NeedHairASAP]

this is crazy... no one even knows if histogen is going to work and you're all already arguing about the price!?

Even if it costs 50K, I wouldn't care... at least I'll know that there are options

truth. +1

way way too early to talk pricing and distribution

[Maradona]

Ugh its gonna be so hard not to get hopes up. Can you imagine the feeling knowing that a legitimate treatment is only a 4 years off? It will be crushing if April comes and Replicel announces they achieved 0% results. 10-15% I can live with, because the methodology can be improved and hopefully compounded, but if the result is 0%, then this generation of hair loss sufferers is probably screwed.

I bought my gun already if there's 0% growth Bro.

Nah man...calm down...let's just enjoy we don't know for now. I have high hopes though since the CEO said "totally expect to beat propecia" n they had 10 years to put that stuff on someone's scalp...come on it's safe treatment I'd take 40 litters of replicels sauce on my scalp any day.

We still have ARI though, but I don't think that would make us look like rockstars....still better than SHINY BALD HEAD I hate that *!#@.

[Kiwi]

this is crazy... no one even knows if histogen is going to work and you're all already arguing about the price!?

Even if it costs 50K, I wouldn't care... at least I'll know that there are options

We know it provides results. So what do you mean "work"?

If we're all out there saying I'll pay $50K and they see it you're providing them info that we'd all pay $50K.

Engage PR brains people! Lets plant the $10K story now and incept them. Say after me "we'd only ever pay $10K for Histogen or Replicel" :P

[Hair Bear]

Actually it would be in there best interest to provide a service at a reasonable price, if they inflate the price they will only be able to gauge a small portion of society however if they keep the costs as low as possible they will see a much great return as it will encourage a larger group of people to undergo the procedure.

One thing I have not seen mentioned here is this, lets just say hypothetically that Histogen, Relicel and Aderans release their finds, procedure and product to the market all at the same time or in succession whilst the choice would be great as they all seem to have a different approach to one another it can may become an issue, for example no one really knows if you are locking yourself out from another competitors procedure if you are already under the care of another, they may not mix.
Let just say you jumped on board Replicel and it did not live up to its claims or you were unhappy with the results...

Its a costly business I'm sure and we are only at the tip of the iceberg really.

[clandestine]

One thing I have not seen mentioned here is this, lets just say hypothetically that Histogen, Relicel and Aderans release their finds, procedure and product to the market all at the same time or in succession whilst the choice would be great as they all seem to have a different approach to one another it can may become an issue, for example no one really knows if you are locking yourself out from another competitors procedure if you are already under the care of another, they may not mix.
Let just say you jumped on board Replicel and it did not live up to its claims or you were unhappy with the results...

This is a very interesting point, and one I had not considered previously. I would hope, as I'm sure others would as well, that this would not be the case. In any case, I would think a person's propensity regarding choice of which company to use is largely, if not totally, dependent on their respective release dates.

[The Alchemist]

I bought my gun already if there's 0% growth Bro.

Nah man...calm down...let's just enjoy we don't know for now. I have high hopes though since the CEO said "totally expect to beat propecia" n they had 10 years to put that stuff on someone's scalp...come on it's safe treatment I'd take 40 litters of replicels sauce on my scalp any day.

I'd say that we probably already know that they will do better than 0% growth. Aderans, who is using a very similar cell based approach, have demonstrated growth in humans. Granted, it wasn't the best and they're now trying to tune up their method. But, none the less, it was growth. Replicel, has a very strong scientific team and a decade of prework behind them, that gives me more confidence in them than Aderans, so i'm hoping they can do substantially better.

Plus, Aderans is significantly further along in the process than replicel, so, they will mostly likely be first to market. It would behoove replicel to get better results than Aderans. If they don't, and Aderans makes it to market first, not only will they not be able to take market share from them, but, they will probably have a more difficult time with the FDA. I believe with medications, new drugs have to provide either better efficacy or better safety profiles than existing FDA approved treatments, or else there is a tendency for them to be rejected. My guess is Replicel is very aware of this. That they're proceeding forward, speaks to their optimism.

My hope is that Aderans does well and shows "good" results from their multi armed trial. And then i hope that Replicel absolutely trounces them.

[ccmethinning]

I wouldn't read to much into Replicel's much discussed "confidence." Being a publicly traded company trading @ $2/share on an over the counter exchange, it is the the CEO's job to be cheerleader and chief and maximize shareholder value by creating as much optimism as possible to increase the share price and to convince suckers (like myself) to buy stock. All without being deliberately misleading of course (notice their language is chosen very carefully).

[Kirby_]

Nah man...calm down...let's just enjoy we don't know for now. I have high hopes though since the CEO said "totally expect to beat propecia" n they had 10 years to put that stuff on someone's scalp...come on it's safe treatment I'd take 40 litters of replicels sauce on my scalp any day.
Even if it's something "just" better than Propecia, and topical/injectable, that would be a big breakthrough, let's be honest... Just think how long Propecia has been on the market without a seriously better (and safer!) treatment overtaking it.

I agree with Hair Bear's point about pricing.

Additionally, I sure hope that as many of these next-gen treatments enter the market as possible, as market competition = (eventually) lower prices.

[Hair Bear]

This is a very interesting point, and one I had not considered previously. I would hope, as I'm sure others would as well, that this would not be the case. In any case, I would think a person's propensity regarding choice of which company to use is largely, if not totally, dependent on their respective release dates.

Yeah I hope it not be the case also however here in lies the problem, a persons choice may be heavily influenced by the release dates and as such it may not be the best decision as someone has mentioned that any other company seeking FDA approval will have to be better than the currently approved option therefore my concerns can and will become relevant it may even hold back the approval as the new company (solution B) may have to prove that it can be used after solution A which has already been approved much to the same way many companies such as histogen have tested that their methods work with human trialist under the influence of minoxodil and or propecia.

[matlondon]

This.

Let's worry about curing it first. Where did the OP get this info? And next time please let us know if you're getting this from the grapevine and aren't actually with Histogen. I got excited for no reason. Anyways, please post a link to your source good sir.

they emailed me.

[jpm]

I'm actually quite excited about HSC. I know more people put they're faith into Replicel and it will (if successfull!!) be the better treatment.

But my understanding is that HSC is the closest to being released and it doesn't require a few months waiting for hair cells to multiply. Therefore you could go in, have a few injections and watch your hair regrow over a year or more, Histogens site says by 75%! Granted this hair would be still susceptible to DHT but if it lasts for 5 years, maybe more on propecia/dut, then if the price was reasonable then I would have no complaints going to have an injection every 5 or more years......

just my thoughts

[NeedHairASAP]

I'm actually quite excited about HSC. I know more people put they're faith into Replicel and it will (if successfull!!) be the better treatment.

But my understanding is that HSC is the closest to being released and it doesn't require a few months waiting for hair cells to multiply. Therefore you could go in, have a few injections and watch your hair regrow over a year or more, Histogens site says by 75%! Granted this hair would be still susceptible to DHT but if it lasts for 5 years, maybe more on propecia/dut, then if the price was reasonable then I would have no complaints going to have an injection every 5 or more years......

just my thoughts


hopefully it grows in well and you don't look like a freak with hair patches all over your head


I question how sufficiently cosmetic the final result will be

[NotBelievingIt]

I wouldn't read to much into Replicel's much discussed "confidence." Being a publicly traded company trading @ $2/share on an over the counter exchange, it is the the CEO's job to be cheerleader and chief and maximize shareholder value by creating as much optimism as possible to increase the share price and to convince suckers (like myself) to buy stock. All without being deliberately misleading of course (notice their language is chosen very carefully).

They are OTC because they are not incorporated in the USA.

If they choose to officially list in the on the NASDAQ or NYSE they have to do a couple things. Namely they must file regularly reports with the SEC. As an OTC they don't have to.

Second, they must incorporate in the USA or incorporate on their native exchange (the TSX) and create whats called an ADR class of share.

[greatjob!]

They are OTC because they are not incorporated in the USA.

If they choose to officially list in the on the NASDAQ or NYSE they have to do a couple things. Namely they must file regularly reports with the SEC. As an OTC they don't have to.

Second, they must incorporate in the USA or incorporate on their native exchange (the TSX) and create whats called an ADR class of share.

Not Correct. They are traded on the newly formed (2010) OTCQB which is the middle tier of the OTC market that does in fact report to the SEC or a U.S. banking regulator.

http://www.otcmarkets.com/content/doc/ps/OTCQBfactsheet.pdf

[NotBelievingIt]

Not Correct. They are traded on the newly formed (2010) OTCQB which is the middle tier of the OTC market that does in fact report to the SEC or a U.S. banking regulator.

http://www.otcmarkets.com/content/doc/ps/OTCQBfactsheet.pdf

I was not aware of that. Their site says the OTCBB so I took that at face value.

[greatjob!]

I was not aware of that. Their site says the OTCBB so I took that at face value.
Sorry I just reread my post and it kind of sounded d*ckish, didn't mean that. Yeah I think there are like three tiers now. the QX is the premium tier and is traded through brokers much like the NYSE and NASDAQ, the QB is the middle tier that is still trader-trader transactions but is comprised of companies that report to and are in good standing with the sec or u.s. banking regulators, the pink sheets is what you typically think of as OTC with trader-trader transactions and limited information disclosure. I think there might be some even more risky tiers but I don't know cause I wouldn’t bother looking at those.