Replicel Trial Update

[krewel]

Hello baldheads,

http://www.replicel.com/replicel-provides-update-on-first-in-man-clinical-trials-and-recent-corporate-activity/

Looks good so far, they're preparing for Phase II!

Best Regards :)

[Sogeking]

So fall 2012 is when phase II studies begin. Good to know. Can't wait. Bald Eagle 1 reporting out. Over.
:)

[Bronson]

Sure wish they were testing more than 100 people. Does anyone have statistics on the safety record of medical products that were tested on only 100 people? Seems to me you would need to test at least 1,000 to get an accurate sense of how safe this would be. I'm sure the first 100 people who took propecia were totally fine too and it was person 100+ that felt the side effects. And yes I know this treatment is autologous (sp?) but none of us are experts and we're using amateur logic to assume this will be safe.

[TxRockClimber]

Perhaps one can take some comfort in the fact that it is a test using your own cells (autogolous) and so far there have been no reported problems with similar therapies. University of Pittsburgh and Wake Forest have used a similar approach (taking stems cells and cultivating them) to produce new bladders, esophagus, etc. without any issues. Besides multiplying the derma sheath cup - they are not doing anything your cells (besides discarding the papilla).

[Follicle Death Row]

Remember guys that phase 1 is using a dose that is an order of magnitude or two higher than what will go to market. Might have been 100 times or even more of the dose they anticipate we'll need. So imagine taking 100mg of fin a day. If phase 1 turns out to be safe then we're in the clear safety wise.

[TxRockClimber]

According to the interview just posted (http://www.baldtruthtalk.com/showthread.php?t=6540&highlight=replicel) - CEO indicates that they have not seen any adverse issues or problems arise in the trial participants...I guess that a few of the participants who were injected at the beginning have already reported back to the clinic for an assessment of their health.

[BoSox]

Safety will not be an issue about Replicel, I have confidence in that.
I can't wait for the next few months, we'll get our awnser <3

[Thinning@30]

I'm glad that Replicel seems to be moving along with its trials and that its management is very optimistic about the possible results, but I am still disappointed with the estimated time to market being 2015 at the soonest. These things always seem to take longer than expected, so if 2015 is the ETA, then who knows when it will really be released. Of course, even if the 2015 estimate is accurate, this wouldn't necessarily mean the product would be relased on January 1, 2015 and be immediately available to anyone who wants it. If the company is not on top of this, there could be real lags with distribution and with training physicians in the new procedures.

I am also disappointed that in the interview, the CEO seemed to indicate that the product will undergo a full three-phase set of clinical trials, and there was no mention of an early release in non-Western countries following the completion of the Phase I safety or Phase II dosing trials. I think many of us were hoping for something like this, so that those of us willing to travel could benefit from the product sooner. There was also no mention of the controversy surrounding whether the U.S. FDA has the right to regulate autologous cell treatments, and the potential for a quicker time to market should the U.S. courts side against the FDA.

[uninformed]

Collaborative Research Agreement
RepliCel has entered into a three year collaborative research agreement with First Affiliated Hospital of Sun Yat-Sen University in China and its head of Dermatology, Dr. Xingqi Zhang, for the development of cell culture methodology for mesenchymal hair follicles. The research will involve blinded studies on optimizing cell culture.

Interesting, that university is from where i grew up. It is the best university in southern china. Maybe i'll go check it out next time i go back :p

[Ted]

What do you guys think will happen if you do a HT and a few years later go through a treatment with Replicel. Will you get super dense hair or will the transplanted hair fall out?

[TxRockClimber]

Thats a good question - I have read through their paper which covered the pre-clinical trial (animal study) and it did not give any guidance as to what might happen in the situation you describe (http://www.nature.com/jid/journal/v121/n6/full/5602058a.html). At least - I could not discern a definitive statement on what might be expected to happen. I guess that if you follow their theory - one would expect some increased growth to the existing hairs undergoing minaturization from the injected dermal sheath cup cells. But what about the induction/formation of totally new follicles? Betting that might be one of the top ten question/issues to be resolved during the dosing trial which is slated to start in Fall 2012.

[krewel]

What about new hair, will be resistance for DHT?

Again, yes.

[BoSox]

I wonder if I will have any hairs on my head by the time this comes out to even benifit from it :/

[krewel]

Ok but. If someone have just thinning hair, those that you stll have on your head automaticly become resistance for DHT?

Yes, the injected cells migrate to "sick" follicles and "recruit" them to DHT resistant cells, so hair gets thicker again and you stop balding.

I wonder if I will have any hairs on my head by the time this comes out to even benifit from it :/

Why shouldn't you benefit from it? If their method really works, you will be able to restore a full head of hair. They just need that little biopsy from the back of your head. That's it.

[CVAZBAR]

If RepliCel works the way the claim, you should be able to not just restore hair but also add more density right? In other words, inject more cells to where you already have hair. So I was wondering, if people would also use it in the donor area. For example, old people who have very thin donor hair. Would you be able to add more density to the WHOLE HEAD? I figured that would be key since donor hair also thins, mAybe not at the same pace but with time it can and it will. What you guys think? Density everywhere would be nice!

[Follicle Death Row]

If RepliCel works the way the claim, you should be able to not just restore hair but also add more density right? In other words, inject more cells to where you already have hair. So I was wondering, if people would also use it in the donor area. For example, old people who have very thin donor hair. Would you be able to add more density to the WHOLE HEAD? I figured that would be key since donor hair also thins, mAybe not at the same pace but with time it can and it will. What you guys think? Density everywhere would be nice!

Yes, I should think so. It may be useful for people with thinned out donors from FUE who pushed it too far as well. Earliest time though is late 2015 but most likely 2016. :(

[krewel]

The funny thing is, you can do this procedure multiple times. There will be a lot of people who will abuse this treatment, because they'll still think they dont have enough hair. It's like those bodybuilders who keep taking roids because they think they're too thin although they're like 242 lbs, haha.

Right now, I'm just hoping for a confirmation that they're concept really works. That would be a great relief for me. Knowing that there will surely be a solution for hairloss, would make my life much more enjoyable. :)

[CVAZBAR]

Yes, I should think so. It may be useful for people with thinned out donors from FUE who pushed it too far as well. Earliest time though is late 2015 but most likely 2016. :(

Well if this is true, then it would be a cure. I was just wondering if it would be a problem since the donor area would eventually thin. I was trying to think how DHT would play into this. Since the cells are taken from the donor, I figured your "new" hair would grow out thin as well but if you can repeat this and continue add density, I guess the problem is fixed.

Please don't say 2016 FDR. Let's hope it's sooner.

[NotDyingBald]

If only we could meet the guy who got the injection Dec´10... Nearly 1year after he would probably have some things to say :) I wonder if right now he knows for sure: "Fuck, this thing works!"

[krewel]

If only we could meet the guy who got the injection Dec´10... Nearly 1year after he would probably have some things to say :) I wonder if right now he knows for sure: "Fuck, this thing works!"

We should stitch one of them, haha.

[Follicle Death Row]

Well if this is true, then it would be a cure. I was just wondering if it would be a problem since the donor area would eventually thin. I was trying to think how DHT would play into this. Since the cells are taken from the donor, I figured your "new" hair would grow out thin as well but if you can repeat this and continue add density, I guess the problem is fixed.

Please don't say 2016 FDR. Let's hope it's sooner.

Well I hope I'm wrong and it's sooner. I'm not sure if I have this right, I might have to listen back but isn't it going to take 18-24 months for phase 2 and 18-24 months for phase 3? I thought they said they'd start phase 2 around March so I think 2016 seems realistic, not as in the usual 5 years nonsense but actually a definitive timeline for an actual cure; not just ideas and pie in the sky.

I really hope it's sooner, around 2015 and even released elsewhere after phase 2. I just hope the guys in phase 1 sprout a forest in the injection site and the guys in phase 2 get to see some real nice natural cosmetice results.

You know if we knew for absolute certain this would be here by 2016 and do just as it promises then I could relax about the whole thing. It would be so comforting. It would be like Christmas for baldies. :D

Keep the faith guys.

[TxRockClimber]

Krewel,

I would hazard a guess that RepliCel has some idea as to whether or not their approach will "bear any fruit"...If you go back and listen to the interviews with CEO David Hall (on bothe the Bald Truth and Fox News) it would appear that they have at least seen the first 1-2 patients who were injected at the beginning and no safety issues were noticed. Additionally, David Hall told the Tobin Smith that they were pretty confident the RepliCel would generate 20% growth which would match the best resulst seen with Propecia...Or course it is also believed by RepliCel that the injections are permanent and are compoundable. I believe someone mentioned that most companies will understate their expected results so as to "out-perform" Wall Street's expectations. Hope that is the case but we will find out sometime in March 2012...What is noteworthy is the RepiCel results appear to have advantage over Aderan's approach in terms of the distribution of new hair during the pre-clinical work i.e., mouse tests.

[RichardDawkins]

In my opinion they did test this stuff already on themselves :-)

[Follicle Death Row]

What is noteworthy is the RepiCel results appear to have advantage over Aderan's approach in terms of the distribution of new hair during the pre-clinical work i.e., mouse tests.

Absolutely. There's no comparison. Looks like Aderans went down the wrong route and have spunked millions on it and they can't use DSC because Replicel have a patent on it. All that research and money at ARI and they dropped the ball.

[Kampung101]

Absolutely. There's no comparison. Looks like Aderans went down the wrong route and have spunked millions on it and they can't use DSC because Replicel have a patent on it. All that research and money at ARI and they dropped the ball.

Yeah it does seem that Aderans took the route thats not the best one when it comes to this specific cellular technology. But I don't think we should now just write Aderans off. Getting so far in their trail work shows that they have something, even if it can't give the same type of results that Replicel can potentially give.

Though I don't want to put all my hopes into 1 out of the 4 possible future treatments, I'd have to say my confidence is probably the strongest in Replicel and Follica, as these two potential treatments have some great scientific minds behind them, it seems like the guys at Replicel have put in the most amount of time in research, and Follica has come the farthest with clinical trials in having completed phase 2.

[hollywoodkid]

Hey guys, lets not get ahead of ourselves. It's still possible that it doesn't work.

Now, let's say it does. What's this nonsense about 20% regrowth? The way their videos describe the technology, and the explanations we hear from their scientists about how the mechanism works, why and how do they arrive at 20%? Logically speaking (using their logic) should this not be full density?

Now let's say it's only 20% regrowth. Is that 20% of full density, or 20% increase of the hairs on your head? Like if Jason Statham goes in to get this done with his 100 hairs on the top of his head, does he walk out with 120? If that's the case then all of us are here are effed come 2016.

[uninformed]

Hey guys, lets not get ahead of ourselves. It's still possible that it doesn't work.

Now, let's say it does. What's this nonsense about 20% regrowth? The way their videos describe the technology, and the explanations we hear from their scientists about how the mechanism works, why and how do they arrive at 20%? Logically speaking (using their logic) should this not be full density?

Now let's say it's only 20% regrowth. Is that 20% of full density, or 20% increase of the hairs on your head? Like if Jason Statham goes in to get this done with his 100 hairs on the top of his head, does he walk out with 120? If that's the case then all of us are here are effed come 2016.

20% regrowth mean 20% REGROWTH, not 20% increase in hair count. If they are already getting 20% regrowth in phase 1, then it would be more than promising.

[TxRockClimber]

I believe if you read the pre-clinical studies (mouse models) that they conducted in Y2003 and successive years along with the interviews of the CEO (David Hall) on Fox News and Balding Truth...It might be possible to infer that the trial areas were limited to a very small area and the 20% (anticipated) regrowth is from new follicles and rejuvenation of DHT effected follicles. What remains to be answered is whether the treatment is compoundable, how far from the injection site will the dermal cup sheaths impact (i.e., 2-3 cm?) and duration. Reports from the safety trials (Q2 2012) might answer the above questions or at least provide some idea and the dosing trials (starting Q3 2012) should hopefully resolve any doubt or uncertainity.

[Papillion]

Forgive my ignorance but I'm with hollywoodkid on this one.
I briefly looked through some data a while ago about this so might have missed it, but why is everyone thinking this is simply down to 'safety' and not questioning whether the process actually works in humans?

Have they got solid evidence it works because I don't recall seeing where they did, and u only have to look at the responses on the next thread about what ppl think of results conducted on mice, ppl arnt impressed with spectral 7 using such rhetoric so why is everyone convinced of this?

Ofc, like everyone I hope there's foundation to all this, but there seems a wave of enthusiasm over this and it seems little more than theory?

[Bronson]

Forgive my ignorance but I'm with hollywoodkid on this one.
I briefly looked through some data a while ago about this so might have missed it, but why is everyone thinking this is simply down to 'safety' and not questioning whether the process actually works in humans?

Have they got solid evidence it works because I don't recall seeing where they did, and u only have to look at the responses on the next thread about what ppl think of results conducted on mice, ppl arnt impressed with spectral 7 using such rhetoric so why is everyone convinced of this?

Ofc, like everyone I hope there's foundation to all this, but there seems a wave of enthusiasm over this and it seems little more than theory?

It's because Replicel is one of the "big four" or whatever number it is now, and at least appears to be one of the safest routes (i.e. replicating cells instead of adding anything to them). Also they are the most recent company to be very communicative with what their intentions are. The hype will die down in a couple months and then build right before they release their results in March

[DepressedByHairLoss]

I'm glad that Replicel seems to be moving along with its trials and that its management is very optimistic about the possible results, but I am still disappointed with the estimated time to market being 2015 at the soonest. These things always seem to take longer than expected, so if 2015 is the ETA, then who knows when it will really be released. Of course, even if the 2015 estimate is accurate, this wouldn't necessarily mean the product would be relased on January 1, 2015 and be immediately available to anyone who wants it. If the company is not on top of this, there could be real lags with distribution and with training physicians in the new procedures.

I am also disappointed that in the interview, the CEO seemed to indicate that the product will undergo a full three-phase set of clinical trials, and there was no mention of an early release in non-Western countries following the completion of the Phase I safety or Phase II dosing trials. I think many of us were hoping for something like this, so that those of us willing to travel could benefit from the product sooner. There was also no mention of the controversy surrounding whether the U.S. FDA has the right to regulate autologous cell treatments, and the potential for a quicker time to market should the U.S. courts side against the FDA.

Me too, I'm very disappointed that the optimistic ETA appears to be 2015. And I'm also very disappointed that there was no mention of an early release in non-Western countries, and that they're going through a full 3-phase set of clinical trials. Although I certainly appreciate the efforts of these companies (years ago, nobody was doing a damn thing to try to cure baldness), it seems like there is no sense of urgency at all to their efforts to get this out as soon as possible. I mean, I understand they need to prove that this method works effectively and is safe, but in the meantime we all have to live at least 4 more years as balding men, which is just hell for me. Also, since this treatment is autologous, I really don't think that they need to do the full 3-phase clinical trial. After all, there are plenty of autologous treatments being performed today that haven't gone through such rigorous clinical trials, or even any clinical trials at all for that matter. PRP or autologous adipose stem cell therapy are perfect examples. I know that PRP doesn't work, but Replicel's method has already obviously exceeded the expectations of PRP in every way. I know that Replicel's method needs to undergo some form of clinical trials, but since their method is autologous, I really don't think that they need to be nearly as extensive as they are now. I mean, 2015 may be an optimistic timeline for some, but that still means that we've got to live shitty, balding lives for at least 4 more years, which is just a terrible option for me. I can't help but think that if some of these scientists that were developing these treatments were actually balding themselves, then maybe they would understand the misery and depression that go along with living life as a balding man, and would get something out to us sooner. I mean, if you don't actually feel for yourself that misery and depression of living life as a balding man, then you can't really know how bad it is.

[NeedHairASAP]

Hey guys, lets not get ahead of ourselves. It's still possible that it doesn't work.

Now, let's say it does. What's this nonsense about 20% regrowth? The way their videos describe the technology, and the explanations we hear from their scientists about how the mechanism works, why and how do they arrive at 20%? Logically speaking (using their logic) should this not be full density?

Now let's say it's only 20% regrowth. Is that 20% of full density, or 20% increase of the hairs on your head? Like if Jason Statham goes in to get this done with his 100 hairs on the top of his head, does he walk out with 120? If that's the case then all of us are here are effed come 2016.

i agree, it should either work or not work... doesn't make sense that it only works a little

[lockness]

Two things that I think are silly that we don't have...a hairloss cure (or substantial treatment) and an electric car that doesn't need petrol whatsoever. We *know* the tech is there, were just stuck dealing with extortionist industries.

[HairTalk]

There's no evidence, at the moment, RepliCel does anything positive with regard to hair restoration, in people. The company currently is performing its first in-human trial, and no results about efficacy have yet been shared (we've been told they will be, around March, 2012).

If the process works, great; but let's not get ahead of ourselves.

[RichardDawkins]

Will work, thats it. There approach is good.

This will stop hair loss and gain new hair or more density. In my opinion has potential for a cure.

Anyway dont be pissed because we dont have a cure, the reason for this is simple, hair loss was never been an issue from a problematic point of view.

Hey even liposuction or stomach decreasing wasnt available since ages, its only getting prominent when demand rises.

And now demand rises in terms of how and with what comapnies can make money and targeting hair loss is an easy goal for them (of course FDA sucks)

Oh and before people argue " They wont bring it to market because the profit will make this vanish because they dont want a cure"

This argument is not true because with a full head of hair they make muc more money. For example

1) combs
2) shampoos
3) conditioners
4) hair spray
5) hair gel
6) colouring hair
7) cutting hair
8) pills and vitamins to make your hair shine

etc etc

And now the question for you if you were in charge

Would you prefer to get money from the all above or would you rely on Propecia and Minox which only a fracture of baldies even use?

I would surely prefere the first option because its much more money and even with us baldies there will be plenty of idiot when they got their hair back, to pay 20 dollars for a shampoo which is said to make your hair shine

[Flowers]

Will work, thats it. There approach is good.

This will stop hair loss and gain new hair or more density. In my opinion has potential for a cure.

Anyway dont be pissed because we dont have a cure, the reason for this is simple, hair loss was never been an issue from a problematic point of view.

Hey even liposuction or stomach decreasing wasnt available since ages, its only getting prominent when demand rises.

And now demand rises in terms of how and with what comapnies can make money and targeting hair loss is an easy goal for them (of course FDA sucks)

Oh and before people argue " They wont bring it to market because the profit will make this vanish because they dont want a cure"

This argument is not true because with a full head of hair they make muc more money. For example

1) combs
2) shampoos
3) conditioners
4) hair spray
5) hair gel
6) colouring hair
7) cutting hair
8) pills and vitamins to make your hair shine

etc etc

And now the question for you if you were in charge

Would you prefer to get money from the all above or would you rely on Propecia and Minox which only a fracture of baldies even use?

I would surely prefere the first option because its much more money and even with us baldies there will be plenty of idiot when they got their hair back, to pay 20 dollars for a shampoo which is said to make your hair shine

Good point. If you have hair, you have to have at least some of that stuff you listed. If you're bald, chances are you're not doing anything about it anyway so I'd say companies who make products for people with hair make more money than companies who make products for bald people

[hollywoodkid]

Just sayin', I sense a change of tone in their pitch, and the language has switched more to a 'preventing' baldness angle vs. reversing baldness:

http://biotuesdays.com/2011/10/18/replicel%E2%80%99s-cell-based-solution-to-hair-loss/

[RichardDawkins]

1) this is from octobre so its in this case not the latest if you consider the interview

2) they talk about both, preventing or stopping hair loss is btw a byproduct of a succesfull cell solution, dont think you get your hair back which was lost and all the remain hair falls out or something

Cells or their genetic material is sucked into dormant follicles or long time dormant ones. There is also a hich chance for a chain effect, if one hair gets reawaken that others around will also get awaken too, but thats more likely of the injection pattern rather then cellular dialogue between follicles.

Also if something stops hair loss this would also mean that all current affected mini vellus hairs would also come back to trminal hair BECAUSE they are in the minituarizing process

[Jundam]

People here need to understand that 20% is not what they are predicting. 10% is what they need to rival the other treatments on the market and continue with phase II dosing trials, 20% or more is what they would want to attract attention and funding from Big Pharma/Big Biotech or independent investors depending on which business module they choose.

You need to understand that they are not running a commercial campaign. They're not trying to peddle a product. All they're doing right now is telling those interested what they are working on and what results they need to see in order to continue working on it.

It always baffles me when people try to predict the outcome of things they do not understand. If the scientists have yet to find an answer, you're probably not going to beat them to the punch by pooling knowledge from forums and Wikipedia.

[HairTalk]

10% is what they need to rival the other treatments on the market and continue with phase II dosing trials, 20% or more is what they would want to attract attention and funding from Big Pharma/Big Biotech or independent investors depending on which business module they choose.

That contradicts what David Hall has said in interviews: 20% or more will allow them to rival current (Nov., 2011) drug threapies for treatment of hairloss. I'm unsure whence you've contrived your "10%" figure.

[Jundam]

I have not gone through all of his interviews and perhaps he has said different elsewhere but in the one I read from BioTuesdays.com he cited 10% as moderately successful and 20% as very successful.

Not that it had anything at all to do with my point.

[Kiwi]

I too read they need 20% growth efficiency to match propecia.

But thats just growth. Will these solutions also halt the balding process. I've been told that Histogen will.

[RichardDawkins]

Yep it will hold the hair loss

[TxRockClimber]

I believe that you will need to listen to the actual interviews - it was either the one on Bald Truth or NBT Equities Research where David Hall (CEO, Replicel) mentioned that they were fairly confident about the 20% result. I do not have any knowledge as to why RepliCel is confident about the above figure - perhaps it was based entirely on the pre-clinical work or some other studies.

[Jundam]

I too read they need 20% growth efficiency to match propecia.

But thats just growth. Will these solutions also halt the balding process. I've been told that Histogen will.

According to the blogpost from Biotuesdays.com it was 10% to match Rogaine and 10-15% to match Propecia but that might have been the site mentioned screwing around with the numbers. I wish people would have read my post and realized the point was that the 20% number was not a prediction but a goal for the clinical trial and that nobody should hang their heads because of it. David Hall also said he believes this could be the cure for male pattern baldness; +20% is not the holy grail they're looking for, it is simply what they would consider a great result from the first phase of their clinical trials.

By the way, for those who don't know, this is not the trial phase where you attempt to optimize efficacy. It's the trial phase where you're really just trying to provide numbers that proves your concept and its safety. Even if it's 20% by the first trial phase it could be 50% by the time it hits the market.

Now go outside, smell a rose, drink a cold beer and try to think of something else until March...

[Bronson]

Now go outside, smell a rose, drink a cold beer and try to think of something else until March...

That's the smartest thing I've read on this forum yet :D

[PatientlyWaiting]

So Replicel is an injection?

If it is, that's what I like to hear. I'm tired of all of these surgeries.

[CVAZBAR]

According to the blogpost from Biotuesdays.com it was 10% to match Rogaine and 10-15% to match Propecia but that might have been the site mentioned screwing around with the numbers. I wish people would have read my post and realized the point was that the 20% number was not a prediction but a goal for the clinical trial and that nobody should hang their heads because of it. David Hall also said he believes this could be the cure for male pattern baldness; +20% is not the holy grail they're looking for, it is simply what they would consider a great result from the first phase of their clinical trials.

By the way, for those who don't know, this is not the trial phase where you attempt to optimize efficacy. It's the trial phase where you're really just trying to provide numbers that proves your concept and its safety. Even if it's 20%
by the first trial phase it could be 50% by the time it hits the market.

Now go outside, smell a rose, drink a cold beer and try to think of something else until March...

I'm not sure that's correct Jundam. I think I remember them saying they would go for injecting maximum amount of cells right off the bat. Maybe someone can confirm this. I can't recall if I read this or heard it in the interview. Or maybe I misunderstood your point in optimizing efficacy.

[uninformed]

I'm not sure that's correct Jundam. I think I remember them saying they would go for injecting maximum amount of cells right off the bat. Maybe someone can confirm this. I can't recall if I read this or heard it in the interview. Or maybe I misunderstood your point in optimizing efficacy.

In a sense yes, because they are injecting a dose many times larger than what they estimate to be an appropriate dose in phase 1 to test for safety.

However, they are not trying different mediums, different ways of injections and what not.

I think at the very least they will try and see if there's compoundable benefits in phase 2. Don't worry mate as Spencer said they are giving a very modest estimate because they don't want to oversell their product. Like many others here I have great confidence in them.

Bring on March!

[Jundam]

I'm not sure that's correct Jundam. I think I remember them saying they would go for injecting maximum amount of cells right off the bat. Maybe someone can confirm this. I can't recall if I read this or heard it in the interview. Or maybe I misunderstood your point in optimizing efficacy.

What the other guy above me said. They will be injecting an enormous amount of replicated cells into the scalp, but as David Hall said earlier they are doing this to test safety rather than efficacy.

In future trials they will probably be experimenting with various methods of cultivating those cells(they already have a deal made and announced with a company in China regarding this I believe), alternative injection methods, possibility of compoundable injections, and I think also the possibility of strengthening the results with post-injection treatments; much like how hair transplant patients use Finasteride after surgery there might be similar approaches to aiding your hair and scalp after injections to improve results.

We might see tremendous results from phase I, but there's no reason to believe that whatever results we see will be the best they can do.

[uninformed]

What the other guy above me said. They will be injecting an enormous amount of replicated cells into the scalp, but as David Hall said earlier they are doing this to test safety rather than efficacy.

In future trials they will probably be experimenting with various methods of cultivating those cells(they already have a deal made and announced with a company in China regarding this I believe), alternative injection methods, possibility of compoundable injections, and I think also the possibility of strengthening the results with post-injection treatments; much like how hair transplant patients use Finasteride after surgery there might be similar approaches to aiding your hair and scalp after injections to improve results.

We might see tremendous results from phase I, but there's no reason to believe that whatever results we see will be the best they can do.

They are partnered with a well known hospital in southern china, my nephew was born there earlier this year actually.

[CVAZBAR]

What the other guy above me said. They will be injecting an enormous amount of replicated cells into the scalp, but as David Hall said earlier they are doing this to test safety rather than efficacy.

In future trials they will probably be experimenting with various methods of cultivating those cells(they already have a deal made and announced with a company in China regarding this I believe), alternative injection methods, possibility of compoundable injections, and I think also the possibility of strengthening the results with post-injection treatments; much like how hair transplant patients use Finasteride after surgery there might be similar approaches to aiding your hair and scalp after injections to improve results.

We might see tremendous results from phase I, but there's no reason to believe that whatever results we see will be the best they can do.
I see what you're saying. That's a good point!

[headlikeafuckingorange]

Interesting. Does anyone know a ball park figure of how much this would cost? Is it a regular treatment like propecia or more of a one-off like a HT.

Just wanting to know whether I should start saving now...

[eqvist]

Interesting. Does anyone know a ball park figure of how much this would cost? Is it a regular treatment like propecia or more of a one-off like a HT.

Just wanting to know whether I should start saving now...

Saving isn´t bad however =)


Is it a crime to talk about the results if you are in a trail?

[uninformed]

Saving isn´t bad however =)


Is it a crime to talk about the results if you are in a trail?

yeh cos you have to sign a nondisclosure contract. the trial is supposed to be double blind,which i assume event replicel don,t know exact results till review day. Furthermore the area is probs so small its hard to see at first without camera

[Morgan137]

Eh, 2015 i think is quitely far for me. So, as one man told before "patience, patience, patience".